Results 21 to 30 of about 137,611 (281)

A case of intraplacental gestational choriocarcinoma; characterised by the methylation pattern of the early placenta and an absence of driver mutations

BMC Cancer, 2019
Background Gestational choriocarcinoma is a rare malignancy believed to arise from the trophoblast cells of the placenta. Despite the frequently aggressive clinical nature, choriocarcinoma has been routinely curable with cytotoxic chemotherapy for over ...
Philip Savage, David Monk, Jose R. Hernandez Mora, Nick van der Westhuizen, Jennifer Rauw, Anna Tinker, Wendy Robinson, Qianqian Song, Michael J. Seckl, Rosemary A. Fisher   +9 more
doaj   +1 more source

Effect of Methane Inhibitors on Ruminal Microbiota During Early Life and Its Relationship With Ruminal Metabolism and Growth in Calves

Frontiers in Microbiology, 2021
The present study aimed to determine whether dietary supplementation with methanogen inhibitors during early life may lead to an imprint on the rumen microbial community and change the rumen function and performance of calves to 49-weeks of rearing ...
Omar Cristobal-Carballo, Omar Cristobal-Carballo, Susan A. McCoard, Adrian L. Cookson, Adrian L. Cookson, Siva Ganesh, Katherine Lowe, Richard A. Laven, Stefan Muetzel   +8 more
doaj   +1 more source

Imprinted Anti-Hemagglutinin and Anti-Neuraminidase Antibody Responses after Childhood Infections of A(H1N1) and A(H1N1)pdm09 Influenza Viruses

mBio, 2023
Immune imprinting is a driver known to shape the anti-hemagglutinin (HA) antibody landscape of individuals born within the same birth cohort. With the HA and neuraminidase (NA) proteins evolving at different rates under immune selection pressures, anti ...
Pavithra Daulagala, Brian R. Mann, Kathy Leung, Eric H. Y. Lau, Louise Yung, Ruipeng Lei, Sarea I. N. Nizami, Joseph T. Wu, Susan S. Chiu, Rodney S. Daniels, Nicholas C. Wu, David Wentworth, Malik Peiris, Hui-Ling Yen   +13 more
doaj   +1 more source

Enhanced selectivity of hydrogel-based molecularly imprinted polymers (HydroMIPs) following buffer conditioning. [PDF]

, 2013
We have investigated the effect of buffer solution composition and pH during the preparation, washing and re-loading phases within a family of acrylamide-based molecularly imprinted polymers (MIPs) for bovine haemoglobin (BHb), equine myoglobin (EMb) and
El-Sharif, HF, Phan, QT, Reddy, Subrayal M   +2 more
core   +1 more source

Sex dependent imprinting effects on complex traits in mice

BMC Evolutionary Biology, 2008
Background Genomic imprinting is an epigenetic source of variation in quantitative traits that results from monoallelic gene expression, where commonly either only the paternally- or the maternally-derived allele is expressed.
Leamy Larry J, Cheverud James M, Hager Reinmar, Wolf Jason B   +3 more
doaj   +1 more source

Reassessment of weak parent-of-origin expression bias shows it rarely exists outside of known imprinted regions

eLife, 2023
In mouse and human, genes subjected to genomic imprinting have been shown to function in development, behavior, and post-natal adaptations. Failure to correctly imprint genes in human is associated with developmental syndromes, adaptive, and metabolic ...
Carol A Edwards, William MD Watkinson, Stephanie B Telerman, Lisa C Hulsmann, Russell S Hamilton, Anne C Ferguson-Smith   +5 more
doaj   +1 more source

The coevolution of sexual imprinting by males and females

Ecology and Evolution, 2016
Sexual imprinting is the learning of a mate preference by direct observation of the phenotype of another member of the population. Sexual imprinting can be paternal, maternal, or oblique if individuals learn to prefer the phenotypes of their fathers ...
Miguel Angel Gómez‐Llano, Eva María Navarro‐López, Robert Tucker Gilman   +2 more
doaj   +1 more source

Loss of Monoallelic Expression of IGF2 in the Adult Liver Via Alternative Promoter Usage and Chromatin Reorganization

Frontiers in Genetics, 2022
In mammals, genomic imprinting operates via gene silencing mechanisms. Although conservation of the imprinting mechanism at the H19/IGF2 locus has been generally described in pigs, tissue-specific imprinting at the transcript level, monoallelic-to ...
Jinsoo Ahn, Joonbum Lee, Joonbum Lee, Dong-Hwan Kim, In-Sul Hwang, In-Sul Hwang, Mi-Ryung Park, In-Cheol Cho, Seongsoo Hwang, Kichoon Lee, Kichoon Lee   +10 more
doaj   +1 more source

Do social insects support Haig's kin theory for the evolution of genomic imprinting?

Epigenetics, 2017
Although numerous imprinted genes have been described in several lineages, the phenomenon of genomic imprinting presents a peculiar evolutionary problem.
Mirko Pegoraro, Hollie Marshall, Zoë N. Lonsdale, Eamonn B. Mallon   +3 more
doaj   +1 more source

NNAT and DIRAS3 genes are paternally expressed in pigs

Genetics Selection Evolution, 2007
Although expression and epigenetic differences of imprinted genes have been extensively characterised in man and the mouse, little is known on livestock species.
Lei Ming-Gang, Li Feng-E, Xiong Yuan-Zhu, Jiang Cao-De, Deng Chang-Yan, Zhang Feng-Wei, Cheng Huan-Chen   +6 more
doaj   +1 more source