Transcriptional profiling at the DLK1/MEG3 domain explains clinical overlap between imprinting disorders. [PDF]
Sci Adv, 2019 Abi Habib W +11 more
europepmc +1 more source
Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition
Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy +7 more
wiley +1 more source
Early‐life adverse events and risk of inflammatory bowel disease: A Scandinavian birth cohort study
Journal of Pediatric Gastroenterology and Nutrition, EarlyView.Abstract Objectives The experience of childhood stressful or adverse life events is believed to imprint on immunological pathways and, therefore, might have lasting effects on inflammatory bowel disease (IBD) development. This study aimed to examine the association between experiences of early‐life adverse events and later IBD risk. Methods We followed
Ida Sigvardsson +6 more
wiley +1 more source
Molecular and Clinical Opposite Findings in 11p15.5 Associated Imprinting Disorders: Characterization of Basic Mechanisms to Improve Clinical Management. [PDF]
Int J Mol Sci, 2019 Wesseler K, Kraft F, Eggermann T.
europepmc +1 more source
Journal of Quaternary Science, EarlyView.ABSTRACT The Cadí Massif (42°17′09″ N, 1°38′11″ E; 2649 m a.s.l.) in the southeastern Pyrenees preserves clear evidence of Late Pleistocene glaciation, although previous research has focused almost exclusively on its northern slope. By contrast, the southern slope has remained largely unexplored.
M. Oliva +5 more
wiley +1 more source
Rapid Postmortem Temporal Bone Extraction and Dissection of Human Inner Ear Organs From Organ Donors
The Laryngoscope, EarlyView.We developed a postmortem protocol for temporal bone extraction and dissection in organ donors, enabling atraumatic bilateral temporal bone retrieval within 1–2 h of ischemia, followed by stepwise microsurgical dissection of neurosensory organs. Combining rapid extraction, abbreviated decalcification, and atraumatic microsurgical dissection, this ...
Yassine Balhi +10 more
wiley +1 more source
From Planar to 3D Nanophotonic Lenses: Advancing Design, Fabrication, and Applications
Laser &Photonics Reviews, EarlyView.Three‐dimensional nanophotonic lenses are enabled by an integrated workflow that links design parameterization, full‐wave electromagnetic simulation, computational optimization, and freeform fabrication. This Review summarizes how these tools expand optical design freedom beyond a single patterned plane by enriching the local meta‐atom response and ...
Wei Zhu +2 more
wiley +1 more source
An Update on Molecular Diagnostic Testing of Human Imprinting Disorders. [PDF]
J Pediatr Genet, 2017 Grafodatskaya D +3 more
europepmc +1 more source
Mass Spectrometry Reviews, EarlyView.ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley +1 more source
Bone Adaptation and Labor Organization in Co‐Located Medieval Anatolian Populations
International Journal of Osteoarchaeology, EarlyView.ABSTRACT Skeletal evidence from geographically co‐located populations offers a rare opportunity to disentangle subsistence‐driven bone adaptation from socially organized labor. This study examines upper limb morphology in two Byzantine communities—the urban center of Tyana (10th–13th c.
Gökhan Çakan +5 more
wiley +1 more source