Results 111 to 120 of about 497,128 (308)

Large Scale In Silico Screening on Grid Infrastructures [PDF]

, 2006
Large-scale grid infrastructures for in silico drug discovery open opportunities of particular interest to neglected and emerging diseases. In 2005 and 2006, we have been able to deploy large scale in silico docking within the framework of the WISDOM ...
Breton, V., Chen, H. -Y., Ho, L. -Y., Hofmann, M., Jacq, N., Kasam, V., Lee, H. -C., Legré, Y., Lin, S. -C., Maass, A., Medernach, E., Merelli, I., Milanesi, L., Rastelli, G., Reichstadt, M., Salzemann, J., Schwichtenberg, H., Sridhar, M., Wu, Y. -T., Zimmermann, M.   +19 more
core   +2 more sources

Photoswitching Conduction in Framework Materials

Advanced Functional Materials, EarlyView.
This mini‐review summarizes recent advances in state‐of‐the‐art proton and electron conduction in framework materials that can be remotely and reversibly switched on and off by light. It discusses the various photoswitching conduction mechanisms and the strategies employed to enhance photoswitched conductivity.
Helmy Pacheco Hernandez, Stefan Hecht, Wolfgang Wenzel, Lars Heinke, Mariana Kozlowska   +4 more
wiley   +1 more source

Bioinformatics Screening of Phenylpropanoids from Pyrostegia venusta in ER+ Breast Cancer

Medical Sciences Forum
This study investigated the cytotoxic, antiproliferative, and molecular interaction profiles of the phenylpropanoids verbascoside and isoverbascoside from Pyrostegia venusta using in silico approaches.
Ana Carolina Maldonado da Costa e Silva, Samara Maria Piccirillo de Brito, Jhuan Luiz Silva, Alex Luiz Pereira, Giulia Maria Camara Leme, Luiz Henrique Cruz, Isabela Cristina Gomes Honório, Juliana da Silva Coppede, Silvio de Almeida-Junior   +8 more
doaj   +1 more source

MLH1 gene: An in silico analysis

Journal of Computational Biology and Bioinformatics Research, 2013
The MLH1 gene responsible for colon cancer has been examined to identify functional consequences of single-nucleotide polymorphisms (SNPs). 16 SNPs have been identified in the MLH1 gene in which all are found to be nonsynonymous. Non synymous SNPs are relevant in many of the human inherited diseases since they change the aminoacid sequence of the ...
openaire   +2 more sources

In silico Analysis and Site-directed Mutagenesis of Promoters

BIO-PROTOCOL, 2017
In normal as in cancerous cells, gene expression is tightly regulated by transcription factors, which are responsible for up- or down-regulation of thousands of targets involved in different cell processes. Transcription factors can directly regulate the expression of genes by binding to specific DNA sequences known as response elements. Identification
Salah Boudjadi, Jean-François Beaulieu
openaire   +4 more sources

Strategies for Loading and Releasing Peptide Therapeutics in Biodegradable Carriers

Advanced Functional Materials, EarlyView.
A biodegradable carrier‐based peptide delivery system is a powerful treatment platform for diverse diseases, owing to its superior therapeutic efficacy and low toxicity. This review examines the conventional peptide‐loaded carrier fabrication process and its current limitations.
Wookyoung Jang, Ki Wan Bong
wiley   +1 more source

Buku Ajar Berbasis Penelitian In Silico pada Matakuliah Teknik Analisis Biologi Molekuler untuk Mahasiswa Strata 1 Biologi

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan, 2018
: The aim of this research is developing textbook based in silico research result for Molecular Biology Engineering and Analysis. The development of this textbook is based on the results of the need assessments of the Biology students who have taken ...
Nanda Hilda Khikmawati, Mohamad Amin, Endang Suarsini   +2 more
doaj   +1 more source

Computational Modeling Meets 3D Bioprinting: Emerging Synergies in Cardiovascular Disease Modeling

Advanced Healthcare Materials, EarlyView.
Emerging advances in three‐dimensional bioprinting and computational modeling are reshaping cardiovascular (CV) research by enabling more realistic, patient‐specific tissue platforms. This review surveys cutting‐edge approaches that merge biomimetic CV constructs with computational simulations to overcome the limitations of traditional models, improve ...
Tanmay Mukherjee, Mehdi Salar Amoli, Sarah Rezapourdamanab, Lama Rita El Shammas, Martin L. Tomov, Emilio A. Mendiola, Vahid Serpooshan, Reza Avazmohammadi   +7 more
wiley   +1 more source

The Combined Use of in Silico, in Vitro, and in Vivo Analyses to Assess Anti-cancerous Potential of a Bioactive Compound from Cyanobacterium Nostoc sp. MGL001

Frontiers in Pharmacology, 2017
Escalating incidences of cancer, especially in developed and developing countries, demand evaluation of potential unexplored natural drug resources. Here, anticancer potential of 9-Ethyliminomethyl-12-(morpholin-4-ylmethoxy)-5,8,13,16-tetraaza -hexacene ...
Niveshika, Ekta Verma, Shashank K. Maurya, Rajnikant Mishra, Arun K. Mishra   +4 more
doaj   +1 more source

Gastrointestinal endogenous proteins as a source of bioactive peptides : Doctor of Philosophy in Nutritional Sciences at Riddet Institute, Massey University, Palmerston North, New Zealand [PDF]

, 2016
Gastrointestinal endogenous proteins (GEP) were investigated as a source of bioactive peptides. In silico and in vitro methods were used singly or in combination to study GEP-derived peptides after simulated digestion.
Acharya, Prasannalakshmi
core