Results 71 to 80 of about 497,128 (308)

In Silico Analysis of Crustacean Hyperglycemic Hormone Family [PDF]

open access: yesMarine Biotechnology, 2005
Through multiple sequence alignment and phylogenetic analysis, the subgrouping of the crustacean hyperglycemic hormone (CHH) family was updated using the most complete, nonredundant sequence data set. All sequences from insects were clustered into a distinct subbranch with characters closer to CHH subfamily I.
S H, Chen, C Y, Lin, C M, Kuo
openaire   +2 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Novel bone morphogenetic protein 15 (BMP15) gene variants implicated in premature ovarian insufficiency

open access: yesReproductive Biology and Endocrinology, 2022
Background Bone morphogenetic protein 15 (BMP15) is expressed in oocytes and plays a crucial role in the reproduction of mono-ovulating species. In humans, BMP15 gene mutations lead to imperfect protein function and premature ovarian insufficiency.
Fatemeh Afkhami   +3 more
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

In vitro and in vivo evaluation of cephalosporins for the treatment of Lyme disease. [PDF]

open access: yes, 2018
BackgroundLyme disease accounts for >90% of all vector-borne disease cases in the United States and affect ~300,000 persons annually in North America.
Ambati, Aditya   +9 more
core  

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

New insights into the association between AXIN2 148 C/T, 1365 C/T, and rs4791171 A/G variants and cancer risk

open access: yesCancer Cell International, 2019
Background Many epidemiological studies have investigated association of AXIN2 variants on overall cancer risks; however, the available results remain inconsistent.
Bin Xu   +6 more
doaj   +1 more source

Analysis of BAC end sequences of tilapia (Oreochromis niloticus) using in silico approaches (W046) [PDF]

open access: yes, 2011
Tilapias are the second most important fish group in aquaculture and a primary source of animal protein for millions of people in developing countries. Over the past years a great effort has been done to increase the genomic tools in tilapia by obtaining
Baroiller, Jean-François   +5 more
core  

Genome-driven evolutionary game theory helps understand the rise of metabolic interdependencies in microbial communities [PDF]

open access: yes, 2017
Metabolite exchanges in microbial communities give rise to ecological interactions that govern ecosystem diversity and stability. It is unclear, however, how the rise of these interactions varies across metabolites and organisms.
Segre, Daniel, Zomorrodi, Ali R.
core   +2 more sources

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

open access: yesFEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca   +6 more
wiley   +1 more source

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