Results 11 to 20 of about 620,275 (284)
Journal of Chemical Theory and Computation, 2021 Many important processes affecting the earth's climate are determined by the physical properties of seawater. In addition, desalination of seawater is a significant source of drinking water for the human population living in coastal areas. Since the physical properties of seawater governing these processes depend on the molecular interactions among its
Ivan M. Zeron +4 more
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Orvosi Hetilap, 2016 Introduction: Simulation models can contribute substantially to our understanding and ability to control the dynamic processes underlying impaired glucose metabolism in diabetic patients. Aim: The aim of this paper is to outline a new comprehensive, physiologically-based dynamic model of glucose homeostasis incorporating up-to-date quantitative ...
DiĂł, MihĂĄly +2 more
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Frontiers in Pharmacology, 2015 While many drug discovery research programs aim to develop highly selective clinical candidates, their clinical success is limited because of the complex non-linear interactions of human brain neuronal circuits.
Hugo eGeerts +4 more
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Insulin sensitivity in critically ill patients: are women more insulin resistant?
Annals of Intensive Care, 2021 Background Glycaemic control (GC) in intensive care unit is challenging due to significant inter- and intra-patient variability, leading to increased risk of hypoglycaemia. Recent work showed higher insulin resistance in female preterm neonates.
Vincent Uyttendaele +5 more
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How can we discover developable antibody-based biotherapeutics?
Frontiers in Molecular Biosciences, 2023 Antibody-based biotherapeutics have emerged as a successful class of pharmaceuticals despite significant challenges and risks to their discovery and development.
Joschka Bauer +10 more
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Synthesis, In Silico Studies, Antiprotozoal and Cytotoxic Activities of Quinoline‐Biphenyl Hybrids [PDF]
, 2020 This is the pre-peer reviewed version of the following article: Synthesis, In Silico Studies, Antiprotozoal and Cytotoxic Activities of Quinoline‐Biphenyl Hybrids, which has been published in final form at https://doi.org/10.1002/slct.201903835.
Carda, Miguel +6 more
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Cancer Informatics, 2016 The plethora of available disease prediction models and the ongoing process of their application into clinical practice – following their clinical validation – have created new needs regarding their efficient handling and exploitation.
Nikolaos A. Christodoulou +5 more
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Journal of Cheminformatics, 2019 Owing to the increase in freely available software and data for cheminformatics and structural bioinformatics, research for computer-aided drug design (CADD) is more and more built on modular, reproducible, and easy-to-share pipelines.
Dominique Sydow +3 more
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Combined in silico/in vivo analysis of mechanisms providing for root apical meristem self-organization and maintenance. [PDF]
, 2012 Background and aimsThe root apical meristem (RAM) is the plant stem cell niche which provides for the formation and continuous development of the root.
Doroshkov, AV +8 more
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Protein aggregation in silico [PDF]
Trends in Biotechnology, 2007 Protein aggregation is a challenge to the successful manufacture of protein therapeutics; it can impose severe limitations on purification yields and compromise formulation stability. Advances in computer power, and the wealth of computational studies pertaining to protein folding, have facilitated the development of molecular simulation as a tool to ...
Troy, Cellmer +3 more
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