Results 31 to 40 of about 497,128 (308)

In Silico Analysis of Huntingtin Homologs in Lower Eukaryotes [PDF]

International Journal of Molecular Sciences, 2021
Huntington’s disease is a rare neurodegenerative and autosomal dominant disorder. HD is caused by a mutation in the gene coding for huntingtin (Htt). The result is the production of a mutant Htt with an abnormally long polyglutamine repeat that leads to pathological Htt aggregates.
Valentina Brandi, Fabio Polticelli
openaire   +2 more sources

Characterization of pinctada fucata mantle gene 2 (pfmg2) in pearl oyster

Biotechnology & Biotechnological Equipment, 2017
Biomineralization is a complicated process which involves multiple gene products in Pinctada fucata. Here, Pinctada fucata mantle gene 2 (pfmg2) was characterized in P. fucata. The putative PFMG2 protein has a Calponin Homology (CH) domain and an EF hand
Xiaoyan Wang, Liyuan Li, Shangfeng Liu, Zhao Wang   +3 more
doaj   +1 more source

In silico Analysis of qBFR4 and qLBL5 in Conferring Quantitative Resistance Against Rice Blast

Journal of Pure and Applied Microbiology, 2018
The devastating yield losses caused by rice blast can be mitigated by breeding resistant cultivars with QTLs enriched with resistance (R-gene) and defence related genes. These genes are the arsenal of the plant’s immune system against pathogen invasion.
Ilakiya Sharanee Kumar, Nurul Aniss Amran, Kalaivani Nadarajah   +2 more
doaj   +1 more source

Variable predicted pathogenic mechanisms for novel MECP2 variants in RTT patients

Journal of Genetic Engineering and Biotechnology, 2022
Background Methyl CpG binding protein 2 (MeCP2) is essential for the normal function of mature neurons. Mutations in the MECP2 gene are the main cause of Rett syndrome (RTT). Gene mutations have been identified throughout the gene and the mutation effect
Wessam E. Sharaf-Eldin, Mahmoud Y. Issa, Maha S. Zaki, Ayman Kilany, Alaaeldin G. Fayez   +4 more
doaj   +1 more source

Fluctuating Nonlinear Spring Model of Mechanical Deformation of Biological Particles [PDF]

, 2015
We present a new theory for modeling forced indentation spectral lineshapes of biological particles, which considers non-linear Hertzian deformation due to an indenter-particle physical contact and bending deformations of curved beams modeling the ...
Gijs J L Wuite, Joost Snijder, Kenneth A Marx, Olga Kononova, Valeri Barsegov, Wouter H Roos, Yaroslav Kholodov   +6 more
core   +4 more sources

IN SILICO ANALYSIS OF A PUTATIVE MOLYBDENUM TRANSPORTER (MoT) IN BUFFALO [PDF]

Exploratory Animal and Medical Research, 2018
Almost all living organism require to transport molybdenum (Mo) from outside cellular milieu for maintenance of essential life processes. Mo is serving as cofactor for catalytic activity of xanthine dehydrogenase, aldehyde oxidase and sulphite oxidase ...
Santanu Panda, Jai Kumar Kaushik, Ashok Kumar Mohanty   +2 more
doaj  

Exact Microsatellite Density Differences among Capsicum Tissues and Development Stages

Journal of Agricultural Sciences, 2011
Density and position differences of microsatellites in genomes may indicate important roles of microsatellites in genetic development and regulation of gene expression.
Ahmet Onus, Ayşe İnce, Mehmet Karaca
doaj   +1 more source

In Silico Analysis of the Immunological Landscape of Pituitary Adenomas

Neurosurgery, 2020
Immunotherapy has gained traction in the treatment of solid tumors but the immunological landscape of pituitary adenomas is not well defined. We sought to investigate the immunological composition in pituitary adenomas using RNA deconvolution (CIBERSORTx) on an existing gene expression dataset for pituitary adenomas.We applied an established ...
Jacky T, Yeung, Matthew D, Vesely, Danielle F, Miyagishima   +2 more
openaire   +3 more sources

In silico characterization of coding and non-coding SNPs of the androgen receptor gene

Informatics in Medicine Unlocked, 2021
The Androgen Receptor (AR), an important ligand-dependent nuclear transcription factor, encoded by the AR gene, functions in regulating the cell proliferation, migration, invasion, and apoptosis pathways. Single nucleotide polymorphisms (SNPs) of AR have
Maisha Adiba, Tonmoy Das, Anik Paul, Ashish Das, Sajib Chakraborty, Md Ismail Hosen, A.H.M. Nurun Nabi   +6 more
doaj   +1 more source

In silico analysis of Eucalyptus thioredoxins [PDF]

Genetics and Molecular Biology, 2005
The Eucalyptus Genome Sequencing Project (FORESTs), an initiative from the Brazilian ONSA consortium (Organization for Nucleotide Sequencing and Analysis), has achieved the sequencing of 123.889 EST clones from 18 different cDNA libraries. We have investigated the FORESTs data set to identify EST clusters potentially encoding thioredoxins (TRX).
Barbosa, Aulus Estevão, Marinho, Paulo
openaire   +4 more sources