Results 181 to 190 of about 169,844 (308)

In Silico Design and Evaluation of TcGAPDH as a Vaccine Against Chagas Disease: A Reverse Vaccinology Approach. [PDF]

Acta Parasitol
Nava-Cuamatzi V, Buendia-Corona RE, González-Vázquez MC, Cedillo-Ramirez ML, Carabarin-Lima A.   +4 more
europepmc   +1 more source

3D analysis of catalytic differences of hydrolases by integrating modelling and mutivariate statistics

, 2012
EBERT, CYNTHIA, FOSCATO, MARCO, GARDOSSI, Lucia, FERRARIO, VALERIO, Svendsen, A., KNAPIC, Lorena, Besenmatter, W.   +6 more
core  

Asking the 5 W's for designing next‐generation bioprocessing

AIChE Journal, EarlyView.
Abstract Biotechnology is expanding beyond traditional, centralized fermentation and toward next‐generation bioprocessing paradigms that emphasize flexible deployment outside the laboratory with application‐specific performance. However, many bioprocesses fail to translate beyond proof‐of‐concept into industrially viable systems because early design ...
Sangdo Yook, Karoline Maria Vieira Nogueira, Raj Sukumar, Jenna Miller, Hal S. Alper   +4 more
wiley   +1 more source

In silico design of a multi-epitope pan vaccine targeting Schistosoma species. [PDF]

Genomics Inform
Gandvi D, Jyotishi C, Patel M, Gupta R.
europepmc   +1 more source

Conformational changes of lipases: a comparative study and experimental implications

, 2012
EBERT, CYNTHIA, FATTOR, DIANA, FOSCATO, MARCO, GARDOSSI, Lucia, FERRARIO, VALERIO, KNAPIC, Lorena   +5 more
core  

Population balance modeling and digital design of degree of agglomeration in industrial crystallization

AIChE Journal, EarlyView.
Abstract This study presents a coupled population balance model (PBM) for describing the degree‐of‐agglomeration (DoA) in crystallization by independently tracking total particle and agglomerate number densities. Applied to an industrial active pharmaceutical ingredient, the model outperformed bridge‐counting methods and accurately captured DoA trends ...
Yung‐Shun Kang, Hemalatha Kilari, Neda Nazemifard, C. Benjamin Renner, Yihui Yang, Charles Papageorgiou, Zoltan K. Nagy   +6 more
wiley   +1 more source

In silico design of a matrix (M) protein-based vaccine candidate against Newcastle disease virus. [PDF]

Poult Sci
Kamran Z, Waseem M, Asghar M.
europepmc   +1 more source

Understanding laccases stability and glycosylation effect by integrating computational and experimental studies

, 2012
EBERT, CYNTHIA, Golovleva, L., FATTOR, DIANA, FOSCATO, MARCO, SINIGOI, LORIS, GARDOSSI, Lucia, FERRARIO, VALERIO, Cherykh, A.   +7 more
core  

Decoding Tattoo and Permanent Makeup Pigments: Linking Physicochemical Properties to Absorption, Distribution, Metabolism, and Elimination Profiles Using Quantitative Structure–Activity Relationship (QSAR)‐Based New Approach Methodologies (NAMs)

Advanced Intelligent Discovery, EarlyView.
This study applies QSAR‐based new approach methodologies to 90 synthetic tattoo and permanent makeup pigments, revealing systemic links between their physicochemical properties and absorption, distribution, metabolism, and elimination profiles. The correlation‐driven analysis using SwissADME, ChemBCPP, and principal component analysis uncovers insights
Girija Bansod, Ajay Vikram Singh, Preeti Bhardwaj, Tulika Rai, Sweta Vijay Nakhale, Amruta Shelar, Rajendra Patil, Peter Laux, Andreas Luch, Christopher J. Osgood, Michael W. Stacey   +10 more
wiley   +1 more source

In silico design of novel recombinant antigens containing immunologically relevant regions of wild-type and escape mutant variants of HBsAg. [PDF]

PLoS One
Workneh YA, Sisay DM, Fekadu A, Bika AT, Mogus AT, Sisay Tessema T.   +5 more
europepmc   +1 more source