Results 51 to 60 of about 114,431,160 (255)

hgcA-in-silico-primer-stats

, 2019
Results from in silico PCR of hgcA universal and clade specific primers with 0 and 2 mismatches run for each ...
Elizabeth McDaniel (7519667)
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

In silico study of Bacillus spB201 amylase through protein sequence inspection

Journal of the Arab Society for Medical Research
Background/aim Bioinformatics is the automatic processing of biological information, and it is a helpful tool to study the structure-function relationship of various proteins.
Sameh Ben Mabrouk, Bouthaina Ben Hadj Hmida, Ikram Boukthir, Slim Cherif   +3 more
doaj   +1 more source

Toward in silico Catalyst Optimization [PDF]

, 2022
In this minireview, we overview a computational pipeline that can be used to successfully reproduce the enantiomeric ratios of homogeneous catalytic reactions.
Nicolai, Cramer, Ruben, Laplaza, Markus, Reiher, Clemence, Corminboeuf, Matthew, Wodrich   +4 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Table1_Structural Equation Modeling of In silico Perturbations.XLSX

, 2021
Gene expression is controlled by multiple regulators and their interactions. Data from genome-wide gene expression assays can be used to estimate molecular activities of regulators within a model organism and extrapolate them to biological processes in ...
Kevin Day (4735620), Jian-Liang Li (561531), San-Pin Wu (574058), Tianyuan Wang (274595), Lin Lin (46073), Pierre R. Bushel (9015944), Francesco J. DeMayo (11749931), Jianying Li (168108)   +7 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Predictive Modeling of Proteins Encoded by a Plant Virus Sheds a New Light on Their Structure and Inherent Multifunctionality

Biomolecules
Plant virus genomes encode proteins that are involved in replication, encapsidation, cell-to-cell, and long-distance movement, avoidance of host detection, counter-defense, and transmission from host to host, among other functions.
Brandon G. Roy, Jiyeong Choi, Marc F. Fuchs   +2 more
doaj   +1 more source

In Silico Modelling of the Human Intestinal Microflora [PDF]

, 2002
The ecology of the human intestinal microflora and its interaction with the host are poorly understood. Though more and more data are being acquired, in part using modern molecular methods, development of a quantitative theory has not kept pace with this development.
Derk Jan Kamerman, Michael H. F. Wilkinson   +1 more
openaire   +3 more sources

in-silico-RENAMED-TIPS.tree

, 2014
In silico tree with tips renamed to full species ...
Brant C. Faircloth (143432), Michael G. Branstetter (609954), White, Noor D., Faircloth, Brant C., Noor D. White (3248478), Brady, Séan G., Séan G. Brady (3248475), Branstetter, Michael G.   +7 more
core   +1 more source