Results 21 to 30 of about 169,778 (256)
Structural Equation Modeling of In silico Perturbations [PDF]
Frontiers in Genetics, 2021 Gene expression is controlled by multiple regulators and their interactions. Data from genome-wide gene expression assays can be used to estimate molecular activities of regulators within a model organism and extrapolate them to biological processes in humans.
Jianying Li +12 more
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In Silico Models for Ecotoxicity of Pharmaceuticals [PDF]
, 2016 Pharmaceuticals and their active metabolites are one of the significantly emerging environmental toxicants. The major routes of entry of pharmaceuticals into the environment are industries, hospitals, or direct disposal of unwanted or expired drugs made by the patient.
Roy, Kunal, Kar, Supratik
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Basic & Clinical Cancer Research, 2019 Hyperthermia is a novel method for cancer therapy. To have the best control when heating tissues in hyperthermia, the use of magnetic nanoparticles is suggested.
Zahra Zahedi-Tabar +3 more
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In silico modeling in infectious disease
Drug Discovery Today: Disease Models, 2007 Infectious disease has witnessed the emergence of mathematical modeling a tool of synthesizing data of growing complexity now available to clinicians and basic scientists alike. The purpose of this review is to introduce mathematical tools commonly used to model infectious disease.
Daun, Silvia, Clermont, Gilles
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In silico modelling of DNA nanostructures
Computational and Structural Biotechnology Journal, 2020 The rise of material science and nanotechnology created a demand for a next generation of materials and procedures that can transcend the shaping of simple geometrical nano-objects. As a legacy of the technological progress made in the Human Genome Project, DNA was identified as a possible candidate.
Kekic, Tadija, Barisic, Ivan
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In silico Models of Alcohol Dependence and Treatment [PDF]
Frontiers in Psychiatry, 2012 In this paper we view alcohol dependence and the response to treatment as a recurrent bio-behavioral process developing in time and propose formal models of this process combining behavior and biology in silico. The behavioral components of alcohol dependence and treatment are formally described by a stochastic process of human behavior, which serves ...
Kovatchev, Boris +2 more
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In silico Prediction of Skin Sensitization: Quo vadis?
Frontiers in Pharmacology, 2021 Skin direct contact with chemical or physical substances is predisposed to allergic contact dermatitis (ACD), producing various allergic reactions, namely rash, blister, or itchy, in the contacted skin area.
Giang Huong Ta +2 more
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In-silico modeling of granulomatous diseases [PDF]
Current Opinion in Pulmonary Medicine, 2016 The pathogenesis of genetically complex granulomatous diseases, such as sarcoidosis and latent tuberculosis, remains largely unknown. With the recent advent of more powerful research tools, such as genome-wide expression platforms, comes the challenge of making sense of the enormous data sets so generated. This manuscript will provide demonstrations of
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JOR Spine, 2023 Background A significant hurdle for potential cell‐based therapies is the subsequent survival and regenerative capacity of implanted cells. While many exciting developments have demonstrated promise preclinically, cell‐based therapies for intervertebral ...
Emily E. McDonnell +9 more
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Journal of Xenobiotics, 2023 Bisphenol A (BPA), a compound widely used in industrial applications, has raised concerns due to its environmental impact. As a key component in the manufacture of polycarbonate plastics and epoxy resins used in many consumer products, concerns about ...
Liadys Mora Lagares, Marjan Vračko
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