Results 141 to 150 of about 117,925,879 (224)

Beneficial Role of Natural Polyphenols Against Epilepsy: Greasing the Wheels of Pharmacotherapy Research for Epilepsy

Food Frontiers, Volume 7, Issue 6, November 2026.
ABSTRACT Epilepsy is the most disabling neurological disease that affects all economic classes, age groups, regions, and races. Although many antiseizure drugs are approved for epilepsy treatment, they fail to work in about 30%–40% of patients. Thus, there is a great need to identify better pharmacological agents to treat epilepsy.
Janakiraman Pillai Udaiyappan, Rengasamy Balakrishnan, Manivasagam Muthukumaran Tamilarasan, Subasri Pandian   +3 more
wiley   +1 more source

Dietary Polyphenols as Regulators of Protein Deposition and Muscle Health: Mechanisms, Interactions, and Functional Applications

Food Science &Nutrition, Volume 14, Issue 11, November 2026.
Dietary polyphenols contribute to the regulation of protein deposition and muscle health through multiple interconnected mechanisms. They promote protein synthesis and myogenic differentiation mainly by modulating the PI3K/AKT/mTOR signaling pathway and myogenic regulatory factors, while suppressing excessive protein degradation through regulation of ...
Chen Liu, Mengyi Ren, Xin Lai, Ke Gu, Liqiang Tan, Aimin Wu, Daiwen Chen   +6 more
wiley   +1 more source

Molecular Recognition of Dental Resin Monomers by Salivary Proteins: Integrated Docking, DFT, Molecular Dynamics, and MM/PBSA Analysis

ChemistryOpen, Volume 15, Issue 11, November 2026.
An integrated computational framework reveals distinct interaction patterns of dental resin monomers with key salivary proteins. Bis‐GMA shows the most favorable predicted binding profile, HEMA displays weaker and more variable interactions, and TEGDMA exhibits intermediate behavior.
Ravinder S. Saini, Fahad Hussain Alhamoudi, Rayan Ibrahim H. Binduhayyim, Abdulkhaliq Ali F. Alshadidi, Abdullah Hassan A. Alshehri, Abdulmajeed Okshah, Ahid Amer Alshahrani, Mohamed Saheer Kuruniyan, Vishwanath Gurumurthy, Masroor Ahmed Kanji, Artak Heboyan   +10 more
wiley   +1 more source

Crowder‐specific modulation of hepatitis C virus NS3/4A protease activity and local structural dynamics

Protein Science, Volume 35, Issue 11, November 2026.
Abstract Macromolecular crowding modulates enzyme behavior in crowder‐ and protein‐specific ways, yet its impact on viral proteases, which are often key therapeutic targets, remains unclear. Here, we investigated the hepatitis C virus NS3/4A protease under increasing concentrations of polyethylene glycols (PEGs), ficoll, dextran, and lysozyme using ...
Małgorzata Lobka, Joanna Trylska
wiley   +1 more source

Strain-Dependent Lactic Fermentation Primes Milk Proteins for Gastrointestinal Digestion Under Age-Specific Physiological Conditions. [PDF]

Foods
Ansiliero R, Albiero LOX, Kempka AP.
europepmc   +1 more source

Review on Cassia alata Bioactive Compounds: In silico, in vitro, and in vivo Studies [PDF]

Michelle Natasha Colin, Nur Shelly Ester Claudiana, Annisa Utami Kaffah, Aliya Nur Hasanah, Sandra Megantara Department of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, IndonesiaCorrespondence ...
Claudiana NSE, Megantara S, Kaffah AU, Hasanah AN, Colin MN   +4 more
core  

Site‐specific O‐glycans influence lacritin structure and multimerization in tears

Protein Science, Volume 35, Issue 11, November 2026.
Abstract Lacritin is an abundantly expressed glycoprotein in tear fluid and plays key roles in immune response, tear secretion, and bacterial killing. These biological functions are tightly regulated through several biochemical mechanisms including multimerization, proteolysis, and alternative splicing, especially within its C‐terminal domain.
Vincent Chang, Ryan J. Chen, Isaac Lian, Madilynn Hamilton, Keira E. Mahoney, Jeff Romano, Gordon Laurie, Stacy A. Malaker   +7 more
wiley   +1 more source

Cereal Biomass Valorization for Functional Food Ingredients: Fractionation and Circular Biorefinery Strategies

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 6, November 2026.
ABSTRACT Food processing must transition toward resource‐efficient systems that operate within planetary boundaries. Cereals, as climate‐resilient staples, offer strong potential to valorize nutrient‐rich fractions. Zero‐waste biorefinery concepts and green fractionation technologies, integrated with structure–function principles, enable the conversion
Rahul Biswas, Marjo Pöysä, Samson Adeoye Oyeyinka, Abayneh Getachew Demesa, Savindi Wanninayake, Samuel Perez‐Vega   +5 more
wiley   +1 more source

S100A10 drives fibrinolytic failure in sepsis. [PDF]

Blood Vessel Thromb Hemost
Waisman DM.
europepmc   +1 more source

A nanobiotechnological approach to control non‐persistent aphid‐transmitted plant viruses, based on functionalized virus‐like particles

Annals of Applied Biology, Volume 189, Issue 3, November 2026.
A potyvirus‐derived virus‐like nanoparticle (VLP) interferes in the transmission by aphids of the non‐circulative plant viruses turnip mosaic virus (TuMV, Potyvirus), zucchini yellow mosaic virus (ZYMV, Potyvirus), and cucumber mosaic virus (CMV, Cucumovirus) is also observed. The construct, that consisted of a fusion between a modified TuMV HC‐Pro and
Aranzazu Moreno, Inmaculada Ferriol, Lucia Zurita, Maria Plaza, Rocio Galán‐Cubero, Adriana Urbano‐Bernabé, Alberto Fereres, Fernando Ponz   +7 more
wiley   +1 more source