Results 141 to 150 of about 16,756 (205)

Discovery of RUVBL1 as a Target of the Marine Alkaloid Caulerpin via MS-Based Functional Proteomics. [PDF]

Mar Drugs
Capuano A, D'Urso G, Capasso L, Brancaccio E, Gazzillo E, Carbone M, Mollo E, Lauro G, Chini MG, Bifulco G, Nebbioso A, Casapullo A.   +11 more
europepmc   +1 more source

Artificial Intelligence–Assisted Design of Plant‐Protein Meat Analogues: Integrating Nutrition, Functionality, and Fibrillation‐Based Texturization

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 4, July 2026.
ABSTRACT Plant proteins provide nutritional value and techno‐functional performance, yet their predominantly globular structures often form isotropic gels that lack the fibrous, anisotropic, and water‐retaining network of animal muscle. This review examines plant‐protein meat analogue design as a multi‐objective challenge requiring the simultaneous ...
Amir Amiri, Klaudia Masztalerz, Srishty Maggo, Anika Singh, Vladislav Korolev, Anubhav Pratap‐Singh   +5 more
wiley   +1 more source

Cut or bind? Antigen-specific processing mechanisms define CD4⁺ T cell immunodominant epitopes for SARS-CoV-2 S and N proteins. [PDF]

Genome Med
Álvaro-Benito M, Abualrous ET, Lingel H, Meltendorf S, Holzapfel J, de Diego Valera P, Sticht J, Kuropka B, Clementi C, Kuppler F, Brunner-Weinzierl MC, Freund C.   +11 more
europepmc   +1 more source

N‐Glycosylation Influences the Heterologous Expression of an Unspecific Peroxygenase From Marasmius rotula in Saccharomyces cerevisiae

Microbial Biotechnology, Volume 19, Issue 7, July 2026.
N‐Linked glycosylation is evidently an important factor for the successful heterologous expression of unspecific peroxygenases (UPOs) in Saccharomyces cerevisiae, as demonstrated using a short UPO from Marasmius rotula. By increasing the probability of glycosylation within a sequon, the yield of extracellular UPO can be substantially increased ...
Marina Schramm, Kai‐Uwe Schmidtke, Yvonne Kolaczek, Nico Jehmlich, Martin Hofrichter, Katrin Scheibner   +5 more
wiley   +1 more source

Integrated high‐resolution copy number and histomolecular analysis of diffuse hemispheric glioma, H3 G34‐mutant reveals universal TP53 abnormalities

Brain Pathology, Volume 36, Issue 4, July 2026.
This integrated high‐resolution copy number and histomolecular analysis of diffuse hemispheric glioma, H3 G34‐mutant expands the spectrum of associated genetic changes and underscores the presence of universal TP53 abnormalities at copy number, sequence, and protein expression level, with frequent yet largely unrecognized TP53 copy‐neutral loss of ...
Jorge A. Trejo‐Lopez, Cinthya Zepeda Mendoza, Thomas M. Kollmeyer, Kristen L. Drucker, Vanessa M. Pazdernik, Paul A. Decker, Corinne E. Praska, Jayson Hardcastle, Stephanie Smoley, Matthew Isaacson, Mallika Gandham, Surendra Dasari, Aditya Raghunathan, Caterina Giannini, Gang Zheng, Aaron Wagner, M. Beatriz Lopes, Kar‐Ming A. Fung, JoElle G. Peterson, Andreana L. Rivera, Christopher Rossi, Meggen A. Walsh, Zied Abdullaev, Kenneth Aldape, Martha Quezado, Drew Pratt, Patrick Joseph Cimino, Robert B. Jenkins, Cristiane M. Ida   +28 more
wiley   +1 more source

Bioactive peptides targeting dyslipidemia and atherosclerosis: from computational discovery and data bottlenecks to precision medicine translation. [PDF]

Front Mol Biosci
Yin W, Wang Q, Zeng Z, Xie X.
europepmc   +1 more source

Extracellular matrix and proteolysis: mechanisms driving irreversible changes and shaping cell behavior

The FEBS Journal, Volume 293, Issue 13, Page 3788-3813, July 2026.
Irreversible ECM proteolysis by remodeling enzymes shapes development, homeostasis, and disease. ECM‐degrading proteases display cell specificity and are governed by shared mechanisms, exhibiting functional redundancy in generating matrikines, growth factors, and cytokines.
Inna Solomonov, Orit Kollet, Irit Sagi
wiley   +1 more source

Microbial fermentation as a strategy for the abatement of peanut allergens. [PDF]

Appl Environ Microbiol
Yammoul Guzman N, Mattison CP, Gibbons JG.   +2 more
europepmc   +1 more source

Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape

The FEBS Journal, Volume 293, Issue 13, Page 3991-4013, July 2026.
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto, Naike Casagrande, Emanuele Di Siena, Greta Carobolante, Lucrezia Camicia, Giorgia Schinello, Samanta Muzzin, Enrica Timis, Paola Spessotto, Maurizio Mongiat   +9 more
wiley   +1 more source

A machine learning-based pharmacokinetics predictor (EGFR-PROPK) for EGFR-targeting PROTACs. [PDF]

Commun Chem
Zhang R, Li F, Liu Y, Geng Y, Zhou Y, Zeng L, Bai F.   +6 more
europepmc   +1 more source