Results 121 to 130 of about 117,925,879 (224)

Dataset 7 - Consensus Non-Haemolytic And Non-Toxic Antimicrobial Peptides Identified By Three Prediction Models (CAPTP, ToxinPred3 and ToxTeller) From Peptidomes Derived From Cnidaria Omics Data

Consensus approach using three prediction models (CAPTP, ToxinPred3 and ToxTeller) to identify putative non-haemolytic and non-toxic antimicrobial peptides from peptidomes generated by in silico proteolysis of Cnidaria omics ...
Barroso, Alexandre
core   +1 more source

Peptides Displayed as High Density Brush Polymers Resist Proteolysis and Retain Bioactivity

, 2015
We describe a strategy for rendering peptides resistant to proteolysis by formulating them as high-density brush polymers. The utility of this approach is demonstrated by polymerizing well-established cell-penetrating peptides (CPPs) and showing that the
Michael K. Gilson (1341396), Jacquelin K. Kammeyer (1341393), Dustin T. Crystal (1341390), Jian Yin (64657), Angela P. Blum (1341399), Anthony M. Rush (1334793), Nathan C. Gianneschi (1320738)   +6 more
core   +1 more source

Detection and Excretion Profile of Retatrutide in Human Plasma and Urine by LC‐HRMS: Implications for Antidoping Analysis

Rapid Communications in Mass Spectrometry, Volume 40, Issue 23, 15 December 2026.
ABSTRACT Rationale Retatrutide (LY3437943) is a novel long‐acting triple incretin receptor agonist that targets the glucagon‐like peptide‐1 receptor (GLP‐1R), glucose‐dependent insulinotropic polypeptide receptor (GIPR), and glucagon receptor (GCGR). Its pronounced effects on body composition and metabolic health, combined with increasing off‐label use
Gabriel Reis Alves Carneiro, Isabelle Karine da Costa Nunes, Gustavo Ramalho dos Santos Cardoso, Paola Façanha dos Santos, Monica Costa Padilha, Fábio César Sousa Nogueira, Henrique Marcelo Gualberto Pereira   +6 more
wiley   +1 more source

Sex‐Modulated TACSTD2 Methylation and Hormone‐Receptor Axis Interactions in Glioblastoma: Insights Toward Mechanistic Understanding

Computational and Systems Oncology, Volume 6, Issue 1, December 2026.
Sex‐stratified analyses of the TCGA and CGGA cohorts have identified promoter‐proximal TACSTD2 CpG sites where methylation shows opposite survival associations in males and females, is independent of copy number, and correlates with TACSTD2 expression.
Tahreem Fatima
wiley   +1 more source

Genotoxic mechanisms of Erythrophleum suaveolens stem bark extracts and fractions in MCF-7 breast cancer cells via mitochondrial and non-mitochondrial pathways

Discover Applied Sciences
Erythrophleum suaveolens stem bark (ESSB) exhibits anti-cancer activity against MCF-7 breast cancer cells, but its genotoxic mechanisms remain unclear.
Rahmat A. Adisa, Lateef A. Sulaimon, Kolawole Ekoh, Kolawole Oluwole-Banjo, Olumide Adebesin, Adeleke T. Ogunnaike, Victor C. Obioma, Oluwaseun O. Taofeek, Lukman O. Afolabi, Sani A. Hamza   +9 more
doaj   +1 more source

Genome-Wide Identification and Expression Profiling of Glycosidases, Lipases, and Proteases from Invasive Asian Palm Weevil, Rhynchophorus ferrugineus

Insects
The red palm weevil, Rhynchophorus ferrugineus, is a destructive, invasive pest to a diverse range of palm plantations globally. Commonly used broad-range chemical insecticides for insect control pose high risks to non-target organisms, humans, and the ...
Nazmi Harith-Fadzilah, Mohammad Nihad, Mohammed Ali AlSaleh, Abdulqader Yaslam Bazeyad, Subash-Babu Pandurangan, Kashif Munawar, Arya Vidyawan, Hattan A. Alharbi, Jernej Jakše, Arnab Pain, Binu Antony   +10 more
doaj   +1 more source

ubiquitin mediated proteolysis-html

, 2014
unigenes involved in ubiquitin mediated ...
Karen Fugate (480954)
core   +1 more source

Genome‐Wide Association Studies of Micro‐and Macro‐Mineral Concentrations in Cultivated, Wild and Native Pea

Legume Science, Volume 8, Issue 4, December 2026.
ABSTRACT Pea (Pisum sativum) is a nutrient‐rich crop that can provide essential nutrients needed for human and animal health. Improving its mineral concentration through genetic selection can enhance its nutritional value and help combat micronutrient deficiencies. This study aimed to investigate the genetic basis of the accumulation of eight minerals (
Maryam Bagheri, Carla S. Santos, Diego Rubiales, Osman Zakaria Wohor, Marta W. Vasconcelos   +4 more
wiley   +1 more source

Mechanism and regulation of Arabidopsis polyamine acetylation by NATA1 and NATA2

Protein Science, Volume 35, Issue 12, December 2026.
Abstract Polyamines are crucial for sustaining plant growth and stress resilience. Spermine/spermidine N1‐acetyl transferases (SSATs) regulate polyamine abundance by catalyzing their N‐acetylation, thereby reducing the pool of polyamines and producing other bioactive components.
Umar F. Shahul Hameed, Yann‐Ru Lou, Aleczander Young, Jian Yan, Francisco J Guzmán‐Vega, Ekaterina Aleksenko, Huaiyuan Ma, Pierre Briozzo, Solange Moréra, Georg Jander, Stefan T. Arold   +10 more
wiley   +1 more source

Influence of the Nature of the Cationic Residues on the Activity of the Antimicrobial Peptides of the Lynronne Family

Journal of Peptide Science, Volume 32, Issue 12, December 2026.
Derivatives of Lynronnes with cationic residues substitution were designed and tested in terms of antimicrobial activity, anti‐biofilm activity, mechanism of action, and in vitro toxicity. Lys‐substitution emerges as a promising strategy for improved activity and selectivity, particularly against E. coli. ABSTRACT Most antimicrobial peptides (AMPs) are
Alexis Reinbold, Maxime Gâchon, Jean‐François Cavalier, Laure Genet, Sophie Guillier, Mathilde Lescat, Muriel Serradeil‐Albalat, Linda B. Oyama, Cendrine Nicoletti, Sharon A. Huws, Nicolas Vidal, Fabiano Cavalcanti Fernandes, Andreia Gomes Martins, Stéphane Canaan, Octávio Luiz Franco, Sophie Tronnet, Olga Iranzo, Marc Maresca   +17 more
wiley   +1 more source