Results 121 to 130 of about 16,756 (205)

Development of Functional Soybean‐Enriched Cheese: Identification of Novel Angiotensin‐Converting Enzyme‐Inhibitory and Predicted Dipeptidyl Peptidase IV‐Related Peptides

open access: yesFood Science &Nutrition, Volume 14, Issue 7, July 2026.
This graphical abstract summarizes the development of soybean‐enriched hybrid cheese, its fermentation with proteolytic starter cultures, peptidomic profiling by LC–MS/MS, and the identification of milk‐ and soybean‐derived peptides with angiotensin‐converting enzyme‐inhibitory activity and predicted dipeptidyl peptidase IV‐related bioactivity ...
Mehtap Er Kemal   +2 more
wiley   +1 more source

Heterozygous OGDH Variants Are Involved in Peripheral Neuropathy With Ataxia and Optical Atrophy

open access: yesJIMD Reports, Volume 67, Issue 4, July 2026.
ABSTRACT 2‐oxyglutarate dehydrogenase (OGDH) encodes an E1 component of α‐ketoglutarate dehydrogenase complex that plays a pivotal role in the Krebs cycle. Biallelic variants in OGDH have been reported to cause an early‐onset neurodevelopmental and mitochondrial disorder.
Liedewei Van de Vondel   +13 more
wiley   +1 more source

ACE2‐ and HR2‐Mimetic Peptides Inhibit Replication of Two SARS‐CoV‐2 Variants

open access: yesJournal of Medical Virology, Volume 98, Issue 7, July 2026.
ABSTRACT Several therapeutic approaches to inhibiting severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) focus on blocking the virus's entry mechanism. This can be blocked in two ways: by interacting with the receptor‐binding domain (RBD) of the spike protein and human angiotensin‐converting enzyme 2 (ACE2), and by blocking viral‐cellular ...
Melvin E. Zúñiga‐Hernández   +5 more
wiley   +1 more source

In silico prediction and structural characterization of multifunctional bioactive peptides released from olive proteins

open access: yesJournal of the Science of Food and Agriculture, Volume 106, Issue 9, Page 5463-5482, July 2026.
Abstract BACKGROUND Olive (Olea europaea L.) byproducts, such as seeds and leaves, are abundant agro‐industrial residues and represent underexplored protein sources with potential health relevance. However, the repertoire of bioactive peptides that may be released from olive proteins during gastrointestinal digestion remains poorly characterized.
Teresa Gonzalez‐de la Rosa   +6 more
wiley   +1 more source

Delivery Systems for Therapeutic Genome Editing: Challenges, Innovations, and Future Perspectives

open access: yesMedComm, Volume 7, Issue 7, July 2026.
Schematic illustration of four emerging CRISPR–Cas delivery platforms defined by distinct design principles and structural features: virus‐mimicking nanosystems (e.g., VLPs), cell‐derived extracellular vesicles, cell‐penetrating peptides, and stimuli‐responsive scaffolds. These platforms enable spatiotemporally controlled delivery of RNPs, mRNA, or DNA
Meijia Yang   +9 more
wiley   +1 more source

De Novo Synthesis in Cancer Immunotherapy: Applications and Prospects

open access: yesMedComm, Volume 7, Issue 7, July 2026.
De novo protein design creates novel structures for cancer immunotherapy, integrating rational design principles like modularity and specificity. Leveraging computational tools, it optimizes cytokine engineering, adoptive cellular therapy, and checkpoint regulation to enhance antitumor immunity.
Yang Jin, Yanfeng Wu, Jianhua Luo
wiley   +1 more source

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