Results 41 to 50 of about 596,956 (378)

Suboptimal concordance in testing and retesting results of triple-negative breast carcinoma cases among laboratories: one institution experience

Cancer Cell International, 2019
Background Triple-negative breast carcinoma (TNBC) patients do not benefit from hormone- or human epidermal growth factor receptor 2- (HER2-) targeted therapies. Accurate testing is pivotal for these patients. Methods TNBC cases that were retested at our
Jose De Jesus, Marilin Rosa
doaj   +1 more source

Detection of fluorescence in situ hybridization on human metaphase chromosomes by near-field scanning optical microscopy [PDF]

, 1995
Fluorescence in situ hybridization signals o­n human metaphase chromosomes are detected by a near-field scanning optical microscope. This makes it possible to localize and identify several fluorescently labeled genomic DNA fragments o­n a single ...
Jalocha, A., Jalocha, A., Moers, M.H.P., Moers, M.H.P., Ruiter, A.G.T., van Hulst, N.F.   +5 more
core   +3 more sources

Rapid metaphase and interphase detection of radiation-induced chromosome aberrations in human lymphocytes by chromosomal suppression in situ hybridization [PDF]

, 1990
Chromosomal in situ suppression (CISS)-hybridization of biotinylated phage DNA-library inserts from sorted human chromosomes was used to decorate chromosomes 1 and 7 specifically from pter to qter and to detect structural aberrations of these chromosomes
Cremer, Christoph, Cremer, Thomas, Emmerich, Patricia, Lichter, Peter, Popp, Susanne   +4 more
core   +1 more source

In Situ Gene Expression in Native Cryofixed Bone Tissue

Biomedicines, 2022
Bone is a very complex tissue that is constantly changing throughout the lifespan. The precise mechanism of bone regeneration remains poorly understood.
Krisztina Nikovics, Cédric Castellarin, Xavier Holy, Marjorie Durand, Halima Morin, Abdelhafid Bendahmane, Anne-Laure Favier   +6 more
doaj   +1 more source

Delineation of individual human chromosomes in metaphase and interphase cells by in situ suppression hybridization using recombinant DNA libraries [PDF]

, 1988
A method of in situ hybridization for visualizing individual human chromosomes from pter to qter, both in metaphase spreads and interphase nuclei, is reported.
B Trask, C Cremer, D Pinkel, D Pinkel, D. C. Ward, DA Agard, DJ Brigati, DJ Finney, GA Rappold, GD Johnson, GJ Brakenhoff, H Hamada, HE McDermid, HJ Cooke, J. Borden, JE Landegent, JG White, JR Gosden, JS Waye, L Hens, L Manuelidis, L Manuelidis, L Manuelidis, L Manuelidis, L Manuelidis, L. Manuelidis, LG Davis, M Schardin, MA Dilla Van, ML Mendelsohn, P. Lichter, PG Sealey, PR Langer, RJ Britten, T Cremer, T Cremer, T Cremer, T Cremer, T Maniatis, T. Cremer   +39 more
core   +1 more source

In Situ Hybridization Status of 568 Cases of HER2 Equivocal Breast Cancer

Zhongliu Fangzhi Yanjiu, 2019
Objective To compare the differences between 2013 and 2018 ASCO/CAP HER2 testing guidelines in 568 immunohistochemical HER2 equivocal breast cancer patients and to analyze the accuracy and deficiency of dual-color silver enhanced in-situ hybridization ...
JIANG Yi'na, WANG Bo, ZHOU Can, WANG Hongyan   +3 more
doaj   +1 more source

Imaging of RNA in situ hybridization by atomic force microscopy [PDF]

, 1996
In this study we investigated the possibility of imaging internal cellular molecules after cytochemical detection with atomic force microscopy (AFM). To this end, rat 9G and HeLa cells were hybridized with haptenized probes for 28S ribosomal RNA, human ...
Corput, M.P.C. van de, Grooth, B.G. de, Kalle, W.H.J., Macville, M.V.E., Raap, A.K., Tanke, H.J.   +5 more
core   +3 more sources

A high-resolution anatomical framework of the neonatal mouse brain for managing gene expression data

Frontiers in Neuroinformatics, 2007
This study aims to provide a high-resolution atlas and use it as an anatomical framework to localize the gene expression data for mouse brain on postnatal day 0 (P0).
Jyl Boline, Arthur W Toga
doaj   +1 more source

Fluorescence quenching by high-power LEDs for highly sensitive fluorescence in situ hybridization

Frontiers in Molecular Neuroscience, 2022
Recent technical advances have made fluorescent in situ hybridization (ISH) a pivotal method to analyze neural tissue. In a highly sensitive ISH, it is important to reduce tissue autofluorescence.
Yousuke Tsuneoka, Yusuke Atsumi, Yusuke Atsumi, Aki Makanae, Aki Makanae, Mitsuru Yashiro, Mitsuru Yashiro, Hiromasa Funato, Hiromasa Funato   +8 more
doaj   +1 more source

A Multicolor Fluorescence in situ Hybridization Approach Using an Extended Set of Fluorophores to Visualize Microorganisms

Frontiers in Microbiology, 2019
Fluorescence in situ hybridization (FISH) with rRNA-targeted oligonucleotide probes is a key method for the detection of (uncultured) microorganisms in environmental and medical samples.
Michael Lukumbuzya, M. Schmid, Petra Pjevac, H. Daims   +3 more
semanticscholar   +1 more source