In situ single-pass intestinal perfusion

Results 121 to 130 of about 118,468,089 (143)

Driving Drugs Deeper: Force‐Driven Microneedle Systems for Active Therapy and Their Road Towards Clinical Implementation

Small, Volume 22, Issue 55, 1 October 2026.
Force‐driven microneedles are presented as active therapeutic microdevices that overcome the diffusion limits of conventional patches. By integrating gas generation, magnetic actuation, cavitation, or iontophoresis, these systems drive payloads deeper into tissue, enabling faster, more controlled delivery and highlighting key design principles and ...
Majed Amini +3 more
wiley +1 more source

Expanding the Donor Pool in Pediatric Transplantations: Successful Domino Liver Transplantation From the Youngest Reported Pediatric DCD Donor Using Normothermic Regional Perfusion in the United States

Pediatric Transplantation, Volume 30, Issue 10, October 2026.
ABSTRACT Introduction Normothermic regional perfusion (NRP) during donation after circulatory death (DCD) improves abdominal organ utilization by limiting warm ischemia time. Its application in young pediatric donors remains exceptionally rare; the youngest previously reported DCD‐NRP donor in the United States was 5 years of age.
Anastasia M. Kahan +8 more
wiley +1 more source

Deletion of the sodium leak channel NALCN in dopamine neurons alters D2R‐mediated signalling and psychostimulant responsiveness

The Journal of Physiology, Volume 604, Issue 20, Page 8542-8568, 15 October 2026.
Abstract figure legend The sodium leak channel NALCN is an important contributor to the spontaneous pacemaker activity of midbrain dopamine neurons and is required for proper presynaptic D2 autoreceptor signalling at dopaminergic terminals. Conditional deletion of NALCN in dopamine neurons enhances psychomotor sensitization to amphetamine and cocaine ...
Angelina Rogliardo +16 more
wiley +1 more source

Exchange rate pass-through and volatility: Impacts on domestic prices in four Asian countries [PDF]

The paper undertakes a comparative empirical analysis on the effects of shocks on domestic prices in four Asian countries before and after the financial crisis of 1997. We apply two different estimation methodologies, namely a structural VAR and a single
Sek, Siok Kun, Kapsalyamova, Zhanna
core

Assessment of Ferrous Glycinate Liposome Absorption Using in Situ Single-Pass Perfusion Model

International Journal of Food Engineering, 2017
Liposomes could be employed to improve the absorption of iron. The purpose of this study was to estimate the intestinal permeability of ferrous glycinate liposomes and to assess the effects of phytic acid, zinc and particle size on iron absorption ...
Baomiao Ding, Xiangzhou Yi
exaly +2 more sources

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pharmacokinetics
intestinal permeability
bioavailability

therapeutics
pharmacology
nanoparticles

rats
caco-2 cell
intestinal absorption

Comparision of the phenol red, gravimetric, and synthesized mPEG-PR methods for correcting water flux using the single-pass intestinal perfusion method

European Journal of Pharmaceutical Sciences, 2022
Zhixiang Liu, Tong An
exaly

Bioaccessibility and Absorption of Flavonoid C-glycosides from Abrus mollis Using Simulated Digestion, Caco-2 Cell, and In Situ Single-pass Perfusion Models

Planta Medica, 2021
Baolin Wang, Hao Wang, Xiaolong Hu
exaly

Study on the intestinal permeability of lamivudine using Caco-2 cells monolayer and Single-pass intestinal perfusion

Saudi Journal of Biological Sciences, 2022
Hongqun Qiao
exaly

Exploring the compatibility mechanism of ShengDiHuang Decoction based on the in situ single-pass intestinal perfusion model

Biopharmaceutics and Drug Disposition, 2020
Xiaofei ZHANG, Junbo Zou, Hui Yang
exaly