Results 11 to 20 of about 8,658,473 (396)

Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro

Cell Research, 2020
Dear Editor, In December 2019, a novel pneumonia caused by a previously unknown pathogen emerged in Wuhan, a city of 11 million people in central China. The initial cases were linked to exposures in a seafood market in Wuhan.
Manli Wang, Ruiyuan Cao, Lei-ke Zhang, Xinglou Yang, Jia Liu, Mingyue Xu, Zhènglì Shí, Zhìhóng Hú, Wu Zhong, Gengfu Xiao   +9 more
semanticscholar   +1 more source

In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)

Clinical Infectious Diseases, 2020
Background The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) first broke out in Wuhan (China) and subsequently spread worldwide. Chloroquine has been sporadically used in treating SARS-CoV-2 infection.
Xueting Yao, F. Ye, Miao Zhang, Cheng Cui, Baoying Huang, P. Niu, X. Liu, Li Zhao, Erdan Dong, Chunli Song, S. Zhan, R. Lu, Haiyan Li, W. Tan, Dongyang Liu   +14 more
semanticscholar   +1 more source

Recent Progress in in vitro Models for Atherosclerosis Studies

Frontiers in Cardiovascular Medicine, 2022
Atherosclerosis is the primary cause of hardening and narrowing arteries, leading to cardiovascular disease accounting for the high mortality in the United States.
Jun Chen, Xixi Zhang, Reid C. Millican, Tyler O Lynd, Manas Gangasani, Shubh Malhotra, J. Sherwood, P. Hwang, Younghye Cho, B. Brott, G. Qin, H. Jo, Y. Yoon, H. Jun   +13 more
semanticscholar   +1 more source

In vitro models and ex vivo systems used in inflammatory bowel disease

In vitro models, 2022
Inflammatory bowel disease (IBD) is a chronic, relapsing gastrointestinal condition. Ulcerative colitis and Crohn’s disease are types of inflammatory bowel disease.
Abhishek Joshi, A. Soni, Sanjeev Acharya
semanticscholar   +1 more source

Establishment and Characterization of the First Chinese National Standard for Nucleic Acid Amplification Technology Assays for Hepatitis E Virus Nucleic Acid Detection

Pathogens, 2023
The detection of hepatitis E virus (HEV) RNA is the gold standard for HEV infection diagnosis. In order to address the quality control requirements for HEV RNA detection kits within China, we aimed to establish the first Chinese national standard for HEV
Manyu Li, Yan Wang, Kejian Li, Xiaotian Hao, Haiwei Zhou   +4 more
doaj   +1 more source

In vitro and in vivo inhibition of breast cancer cell growth by targeting the Hedgehog/GLI pathway with SMO (GDC-0449) or GLI (GANT-61) inhibitors. [PDF]

, 2016
Aberrant Hedgehog (Hh)/glioma-associated oncogene (GLI) signaling has been implicated in cancer progression. Here, we analyzed GLI1, Sonic Hedgehog (Shh) and NF-κB expression in 51 breast cancer (ductal carcinoma) tissues using immunohistochemistry ...
Bei, R., Benvenuto, M, Bonanno, E, Cucchi, Danilo, DE SMAELE, Enrico, DI STEFANO, Enrica, Fantini, M, Frajese, Gv, Gulino, Alberto, Masuelli, Laura, Mattera, Rosanna, Modesti, A, Orlandi, A, Screpanti, Isabella   +13 more
core   +1 more source

A standardised static in vitro digestion method suitable for food - an international consensus.

Food & Function, 2014
Simulated gastro-intestinal digestion is widely employed in many fields of food and nutritional sciences, as conducting human trials are often costly, resource intensive, and ethically disputable.
M. Minekus, M. Alminger, P. Alvito, S. Ballance, T. Bohn, C. Bourlieu, C. Bourlieu, F. Carrière, R. Boutrou, R. Boutrou, M. Corredig, D. Dupont, D. Dupont, C. Dufour, L. Egger, M. Golding, S. Karakaya, B. Kirkhus, S. Feunteun, U. Lesmes, A. Macierzanka, A. Mackie, S. Marze, D. Mcclements, O. Ménard, O. Ménard, I. Recio, C. Santos, Rajat Singh, G. Vegarud, M. Wickham, W. Weitschies, A. Brodkorb   +32 more
semanticscholar   +1 more source

Does seminal fluid bacterial isolate(s) affect in vitro fertilization — embryo transfer outcome?

Middle East Fertility Society Journal, 2023
Background The chance of achieving a successful pregnancy through in vitro fertilization and embryo transfer (IVF-ET) is limited despite recent scientific advances in this field due to several factors that are known to affect the outcome.
Rukayya Muhammad Babandi, Rais Shuaibu Ibraheem, Rayyan Muhammad Garba, Idris Muhammed Liman, Amina Ismail-Are, Yakubu Samuel   +5 more
doaj   +1 more source

Transcriptomics Reveals Discordant Lipid Metabolism Effects between In Vitro Models Exposed to Elafibranor and Liver Samples of NAFLD Patients after Bariatric Surgery

Cells, 2022
Background and aims: Non-alcoholic steatohepatitis (NASH) is a life-threatening stage of non-alcoholic fatty liver disease (NAFLD) for which no drugs have been approved.
Joost Boeckmans, Alexandra Gatzios, Anja Heymans, Matthias Rombaut, Vera Rogiers, Joery De Kock, Tamara Vanhaecke, Robim M. Rodrigues   +7 more
doaj   +1 more source

In Vitro Fermentability, Degradability and Microbial Biomass Product of Complete Ration Containing a Combination of Field Grass, Concentrate and Nutrient Rich Supplement [PDF]

, 2009
The objective of this experiment was to obtain an optimum combination between field grass,concentrate and Nutrient Rich Supplement (NRS) based on in vitro study using Hohenheim gas test. Theexperimental diets were: R1 (control diet = 70% field grass + 30%
Suharyono, S. (S), Tjakradidjaja, A. S. (A), Wahyuni, D. S. (D)   +2 more
core   +1 more source