Advanced NanoBiomed Research, EarlyView.Redox responsive mesoporous silica nanoparticles (MSNs) were engineered to deliver gemcitabine (Gem) and cisplatin (cisPt) at defined ratios to overcome chemoresistance in pancreatic ductal adenocarcinoma (PDAC). Optimized Gem MSNs and Gem cisPt MSNs enhanced cytotoxicity in murine and human Gem resistant models, with select formulations inducing ...
Tamanna Binte Huq +5 more
wiley +1 more source
Astragalus Polysaccharide Modulates the Gut Microbiota and Metabolites of Patients with Type 2 Diabetes in an In Vitro Fermentation Model. [PDF]
NutrientsZhang X +10 more
europepmc +1 more source
Tunable Regional Targeting of Self‐Assembling Peptide Nanomaterials in Acute Myocardial Infarction
Advanced NanoBiomed Research, EarlyView.In a rat model of acute myocardial infarction, intravascular delivery of peptide nanofibers with a collagen‐targeting peptide bound to the infarct vasculature while globular peptide nanoparticles penetrated into the infarct area. This study demonstrated that size, shape, and surface chemistry of nanomaterials control the delivery location within the ...
Alexander Chen +14 more
wiley +1 more source
Improvement of intestinal microbial structure in patients with cerebral infarction through in vitro fermentation of anthocyanins from Lycium ruthenicum Murray. [PDF]
Food Sci NutrQiu J, Ye B, Feng L.
europepmc +1 more source
Sustainable Manufacturing Platforms for Closed‐Cycle Bioeconomy Applications
Asia-Pacific Journal of Chemical Engineering, EarlyView.ABSTRACT The transition to a circular bioeconomy requires innovative production platforms that prioritize sustainability, resource efficiency, and waste minimization. Organic waste from agriculture, aquaculture, and food production represents an underutilized feedstock for biomanufacturing, contributing to a circular economy.
Yelizaveta Chernysh +2 more
wiley +1 more source
<i>In vitro</i> fermentation characteristics of dietary fibers using fecal inocula from dogs fed a canned diet and treated with metronidazole. [PDF]
Front Vet SciMartini SE +5 more
europepmc +1 more source
Animal Research and One Health, EarlyView.This study firstly isolated a tuna‐derived gut probiotic Acinetobacter seifertii YFT067. Dietary administration of YFT067 played significant roles in promoting growth performance, SCFAs production, lipid absorption, and metabolism of the host, indicating YFT067 as a promising probiotic candidate for enhancing tuna aquaculture productivity through ...
Ying Zou +4 more
wiley +1 more source
Animal Research and One Health, EarlyView.Activo Liquid and Halquinol inhibit Salmonella and Escherichia coli in culture media. Activo Liquid exhibits bactericidal action, whereas HA is bacteriostatic, and their combination results in positive or indifferent interactions. This combination effectively inhibits E. coli throughout digestion simulation, thus reducing the required concentrations of
Alberto Gonçalves Evangelista +6 more
wiley +1 more source
Colonic in vitro fermentation of mycoprotein promotes shifts in gut microbiota, with enrichment of Bacteroides species. [PDF]
Commun BiolColosimo R +6 more
europepmc +1 more source
Combination of Inulin and Resistant Dextrin Has Superior Prebiotic Effects and Reduces Gas Production During In Vitro Fermentation of Fecal Samples from Older People. [PDF]
NutrientsYoshida K +4 more
europepmc +1 more source