Results 41 to 50 of about 7,607,147 (352)

Learnings and challenges to deploy an interprofessional and independent medical education programme to a new audience

open access: yesJournal of European CME, 2017
The importance of interprofessional education (IPE) in continuing medical education and professional development has long been recognised by health organisations and academic societies, benefiting not only patient outcomes and interprofessional ...
Mieke L. Van Driel   +5 more
doaj   +1 more source

The Design and Preclinical Evaluation of a Single-Label Bimodal Nanobody Tracer for Image-Guided Surgery

open access: yesBiomolecules, 2021
Intraoperative guidance using targeted fluorescent tracers can potentially provide surgeons with real-time feedback on the presence of tumor tissue in resection margins.
Pieterjan Debie   +10 more
doaj   +1 more source

SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo

open access: yesScience, 2020
Changing with the times Pandemic spread of a virus in naïe populations can select for mutations that alter pathogenesis, virulence, and/or transmissibility.
Yixuan J. Hou   +25 more
semanticscholar   +1 more source

Benzotriazole is antiestrogenic in vitro but not in vivo [PDF]

open access: yes, 2007
Copyright © 2007 SETAC. This is the accepted version of the following article: Harris et al (2007), "Benzotriazole is antiestrogenic in vitro but not in vivo", Environmental Toxicology and Chemistry, 26(11), 2367–2372, which has been published in final ...
Brian, JV   +5 more
core   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Beyond the Barrier: Targeted Radionuclide Therapy in Brain Tumors and Metastases

open access: yesPharmaceutics, 2019
Brain tumors are notoriously difficult to treat. The blood-brain barrier provides a sanctuary site where residual and metastatic cancer cells can evade most therapeutic modalities.
Janik Puttemans   +3 more
doaj   +1 more source

Mate genetic similarity affects mating behaviour but not maternal investment in mice

open access: yesScientific Reports, 2023
Maternal investment can affect the survival and development of offspring. Here we experimentally investigated in mice, whether females alter implantation rates and pup survival after embryo transfer depending on the genetic similarity with their ...
Kerstin E. Auer   +4 more
doaj   +1 more source

Neuroprotective effects of carnitinoid compounds in rodent cellular and in vivo models of mitochondrial complex I dysfunction [PDF]

open access: yes, 2019
Rotenone-mediated mitochondrial complex I inhibition was used to model Parkinson’s disease-like syndrome in Lewis rats. Tyrosine hydroxylase immunolabeling demonstrated a decrease in the number of dopaminergic neurons as well as aberrant morphology in ...
Steliou, Kosta
core  

Multimodal wide-field two-photon excitation imaging: characterization of the technique for in vivo applications [PDF]

open access: yes, 2011
We report fast, non-scanning, wide-field two-photon fluorescence excitation with spectral and lifetime detection for in vivo biomedical applications. We determined the optical characteristics of the technique, developed a Gaussian flat-field correction ...
Agadjanian   +28 more
core   +3 more sources

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

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