Results 11 to 20 of about 1,674,283 (217)
Advancements in the Alcohol-Associated Liver Disease Model
Biomolecules, 2022 Alcohol-associated liver disease (ALD) is an intricate disease that results in a broad spectrum of liver damage. The presentation of ALD can include simple steatosis, steatohepatitis, liver fibrosis, cirrhosis, and even hepatocellular carcinoma (HCC ...
Lin Zhu +7 more
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Frontiers in Cellular and Infection Microbiology, 2021 The larvae of the insect Galleria mellonella, have recently been established as a non-mammalian infection model for the Mycobacterium tuberculosis complex (MTBC).
Masanori Asai +7 more
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In Vivo and In Vitro Models to Study Liver Fibrosis: Mechanisms and LimitationsSummary
Cellular and Molecular Gastroenterology and Hepatology, 2023 Liver fibrosis is a common result of liver injury owing to various kinds of chronic liver diseases. A deeper understanding of the pathophysiology of liver fibrosis and identifying potential therapeutic targets of liver fibrosis is important because liver
Young-Sun Lee, Ekihiro Seki
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SERINC5 Potently Restricts Retrovirus Infection
mBio, 2020 The serine incorporator (SERINC) proteins are multipass transmembrane proteins that affect sphingolipid and phosphatidylserine synthesis. Human SERINC5 and SERINC3 were recently shown to possess antiretroviral activity for a number of retroviruses ...
Uddhav Timilsina +4 more
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Bioengineering, 2023 Alveolar cleft is a common congenital deformity that requires surgical intervention, notably using autologous bone grafts in young children. Bone substitutes, in combination with mesenchymal stem cells (MSCs), have shown promise in the repair of these ...
Alban Destrez +5 more
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Animal Models in Human Adenovirus Research
Biology, 2021 Human adenovirus (HAdV) infections cause a wide variety of clinical symptoms, ranging from mild upper respiratory tract disease to lethal outcomes, particularly in immunocompromised individuals.
Luca D. Bertzbach +2 more
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Safety and biodegradability of a synthetic dural sealant patch (Liqoseal) in a porcine cranial model
Animal Models and Experimental Medicine, 2021 Background Liqoseal consists of a watertight layer of poly(ester)ether urethane and an adhesive layer containing polyethylene glycol‐N‐hydroxysuccinimide (PEG‐NHS).
Ahmet Kinaci +5 more
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Orthotopic Transplantation of Human Paediatric High-Grade Glioma in Zebrafish Larvae
Brain Sciences, 2022 Brain tumours are the most common cause of death among children with solid tumours, and high-grade gliomas (HGG) are among the most devastating forms with very poor outcomes. In the search for more effective treatments for paediatric HGG, there is a need
Susanna Larsson +2 more
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In Vitro and In Vivo Models to Study the Zoonotic Mosquito-Borne Usutu Virus
Viruses, 2020 Usutu virus (USUV), a mosquito-borne zoonotic flavivirus discovered in South Africa in 1959, has spread to many European countries over the last 20 years.
Emna Benzarti, Mutien Garigliany
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Medicina, 2022 The incidence and societal burden of cancer is increasing globally. Surgery is indicated in the majority of solid tumours, and recent research in the emerging field of onco-anaesthesiology suggests that anaesthetic-analgesic interventions in the ...
Ryan Howle +2 more
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