Results 21 to 30 of about 1,364,664 (267)
Diabetic retinopathy: a comprehensive update on in vivo, in vitro and ex vivo experimental models
BMC Ophthalmology, 2023 Diabetic retinopathy (DR), one of the leading causes of visual impairment and blindness worldwide, is one of the major microvascular complications in diabetes mellitus (DM). Globally, DR prevalence among DM patients is 25%, and 6% have vision-threatening
Muhammad Zulfiqah Sadikan +9 more
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In vivo Pooled Screening: A Scalable Tool to Study the Complexity of Aging and Age-Related Disease
Frontiers in Aging, 2021 Biological aging, and the diseases of aging, occur in a complex in vivo environment, driven by multiple interacting processes. A convergence of recently developed technologies has enabled in vivo pooled screening: direct administration of a library of ...
Martin Borch Jensen +2 more
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Molecular Therapy: Methods & Clinical Development, 2020 Most antibodies display very low brain exposure due to the blood-brain barrier (BBB) preventing their entry into brain parenchyma. Transferrin receptor (TfR) has been used previously to ferry antibodies to the brain by using different formats of ...
Tuan-Minh Do +25 more
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Vitamin C Deficiency May Delay Diet-Induced NASH Regression in the Guinea Pig
Antioxidants, 2021 Oxidative stress is directly linked to non-alcoholic fatty liver disease (NAFLD) and the progression to steaotohepatitis (NASH). Thus, a beneficial role of antioxidants in delaying disease progression and/or accelerating recovery may be expected, as ...
Josephine Skat-Rørdam +8 more
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Experimental In Vivo Models of Candidiasis [PDF]
Journal of Fungi, 2018 Candidiasis is a multifaceted fungal disease including mucosal-cutaneous, visceral, and disseminated infections caused by yeast species of the genus Candida. Candida infections are among the most common human mycoses. Candida species are the third to fourth most common isolates from bloodstream infections in neutropenic or immunocompromised ...
Esther Segal, Michael Frenkel
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Animals, 2022 Ambient temperature is an important non-biotic environmental factor influencing immunological and oncological parameters in laboratory mice. It is under discussion which temperature is more appropriate and whether the commonly used room temperature in ...
Thomas Kolbe +5 more
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Tissue Models for Neisseria gonorrhoeae Research—From 2D to 3D
Frontiers in Cellular and Infection Microbiology, 2022 Neisseria gonorrhoeae is a human-specific pathogen that causes gonorrhea, the second most common sexually transmitted infection worldwide. Disease progression, drug discovery, and basic host-pathogen interactions are studied using different approaches ...
Motaharehsadat Heydarian +3 more
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Numerical Modeling for In Vivo Electroporation [PDF]
, 2003 Electropermeabilization of cell plasma membrane is a threshold phenomenon. When a cell is exposed to electric field a spatially dependent transmembrane potential is induced (1). Above a certain threshold value of transmembrane potential permeability of plasma membrane drastically increases.
D, Semrov, D, Miklavčič
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Frontiers in Veterinary Science, 2021 Neospora caninum and Toxoplasma gondii are one of the main concerns of the livestock sector as they cause important economic losses in ruminants due to the reproductive failure.
Iván Pastor-Fernández +4 more
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Nanomaterials, 2022 The growing development and applications of nanomaterials lead to an increasing release of these materials in the environment. The adverse effects they may elicit on ecosystems or human health are not always fully characterized.
Valérie Forest
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