Results 111 to 120 of about 117,900,808 (282)

vivo-project/VIVO: Release vivo-1.14.2

<p><strong>Release vivo 1.14.2</strong><br/>It is recommended that you review the 1.14 Documentation and the VIVO/Vitro READMEs on github before you start.<br/>If you are new to VIVO/Vitro it is suggested that you take ...
Jim Blake, Stefan-Wolff, Brian Caruso, Andrew Woods, Nate Prewitt, William Welling, Don Elsborg, hudajkhan, Ralph O'Flinn, Christian Hauschke, Georgy Litvinov, Alex Viggio, tworrall, Ben, Ted Lawless, Miloš Popović, Arfon Smith, vivo-uab, Jon Corson-Rikert, Steve McKay, Mike Conlon, Dragan Ivanovic, Brian Lowe, Stephen V. Williams, Holly Mistlebauer, Michel Héon, Laura Wrubel, Graham Triggs   +27 more
core   +1 more source

Mutagenicity of N-oxide containing heterocycles and related compounds: Experimental and theoretical studies

, 2014
In the development of new drugs, it is very important to know the effects these may bring to those who consume them. Drugs which act upon certain diseases must not cause toxic side effects on healthy organs.
Cerecetto, Hugo, Lavaggi, M. L., Di Maio, R., Gabay, Martín, Cabrera, M., Campillo, Nuria E., Páez, Juan A.   +6 more
core   +1 more source

Targeting homologous recombination repair to potentiate fluoroquinolone efficacy in Mycobacterium abscessus

mLife, EarlyView.
Shuai Wang, Md Shah Alam, Buhari Yusuf, Jingran Zhang, Ziwen Lu, Xiaofan Zhang, H. M. Adnan Hameed, Mst. Sumaia Khatun, Chunyu Li, Lijie Li, Aleksey A. Vatlin, Aweke M. Belachew, Xirong Tian, Yamin Gao, Cuiting Fang, Rogers P. Zhang, Jun Li, Xinyue Wang, Liqiang Feng, Li Wan, Tianyu Zhang   +20 more
wiley   +1 more source

Brief encounters and lasting impressions—How target protein half‐life affects reactive metabolite signaling

The FEBS Journal, EarlyView.
Lipid‐derived reactive electrophile molecules (REMs) are generated from fatty acids through lipoxygenase or cyclooxygenase‐assisted catalysis, or free radical‐induced lipid peroxidation events. REMs so‐produced covalently modify nearby protein‐cysteines, and in the case of ‘first responder’ proteins, can trigger gain‐of‐function signaling with context ...
Marcus J. C. Long, Lorna Birkby, Yimon Aye   +2 more
wiley   +1 more source

Immunomodulatory Peptide LW‐9 Enhances Doxorubicin Efficacy by Downregulating PD‐L1 and Promoting Intratumoral T‐Cell Responses in Murine Breast Cancer

Immunology, EarlyView.
LW‐9, a peptide derived from Phoneutria nigriventer venom, enhances antitumor immunity in a murine breast cancer model by remodelling the tumour microenvironment. Treatment reduces PD‐L1 expression while increasing CD3+ and GITR+ T‐cell infiltration, resulting in delayed tumour progression, particularly when combined with doxorubicin.
Ingrid Mayara Cavalcante Trevisan, Cibele Pereira Mariano, Sabrina Carvalho Brunelli, Gabriel da Silva Cordeiro, Jessika Takaki, Valquiria Aparecida Matheus, Liana Verinaud, Catarina Rapôso   +7 more
wiley   +1 more source

Scientific Opinion on Flavouring Group Evaluation 201 Revision 1 (FGE.201Rev1): 2‐Alkylated, aliphatic, acyclic alpha, beta‐unsaturated aldehydes and precursors, with or without additional double‐bonds, from chemical subgroup 1.1.2 of FGE.19

EFSA Journal, 2012
The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to consider in this revision 1 of Flavouring Group Evaluation 201, the additional data on genotoxicity submitted by the ...
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)
doaj   +1 more source

Implications of European Union Sodium Perborate Restrictions for Intracoronal Bleaching Procedures: A Narrative Review

Journal of Esthetic and Restorative Dentistry, EarlyView.
ABSTRACT Objectives To critically evaluate current and emerging intracoronal bleaching agents and to provide an evidence‐informed framework for clinical decision‐making in the postsodium perborate era. Overview The declining availability of sodium perborate, particularly within the European Union, has substantially altered contemporary intracoronal ...
Marco M. Herz, Christian Meller, Christian Klein, Johannes Österreicher   +3 more
wiley   +1 more source

PbSnRK1‐Mediated Phosphorylation of PbTCP13 Regulates Glucose‐Responsive Lignin Biosynthesis via PbMYB11 During Pear Stone Cell Formation

Plant Biotechnology Journal, EarlyView.
ABSTRACT Stone cell lignification is a key determinant of pear fruit texture and commercial quality, and this process has been reported to be tightly coupled to cellular glucose availability. However, how glucose dose‐dependently targets transcription factor phosphorylation during lignin biosynthesis remains largely unknown.
Jianan He, Xuxu Wang, Abdul Basit, Wen Li, Jiahui Chao, Wenyu Zhao, Mingxu Niu, Xin Yan, Yuanhui Yu, Kaijie Qi, Zhihua Xie, Shaoling Zhang, Katsuhiro Shiratake, Khanizadeh Shahrokh, Shutian Tao   +14 more
wiley   +1 more source

Bacterial Cellulose Dressings from Mango Pulp Agro-Waste Functionalized with Grapefruit Seed Oil for Diabetic Wound Healing

Polysaccharides
Bacterial cellulose (BC) is an emerging biopolymer for skin tissue regeneration; however, its functionalization with natural antimicrobial agents remains limited.
Mayra E. García-Sánchez, Alfonso Barajas-Cervantes, Inés Jiménez-Palomar, José M. Acosta-Cuevas, Erick O. Cisneros-López   +4 more
doaj   +1 more source

Antimicrobial photodynamic therapy in Candida spp. biofilms: In vitro and in vivo protocols

Photochemistry and Photobiology, EarlyView.
This review addresses the critical challenges in translating in vitro antimicrobial photodynamic therapy protocols to in vivo models, with a particular focus on the hurdles of standardization. The vast diversity in photosensitizers and light parameters across different target cells and models requires a rigorous optimization process.
Lívia Mara Alves Figueiredo‐Godoi, Ana Júlia Barbosa Tomé, Cristina Kurachi   +2 more
wiley   +1 more source