Results 11 to 20 of about 2,682,884 (340)

Inborn errors of immunity in adulthood. [PDF]

Allergy Asthma Clin Immunol
Inborn errors of immunity (IEIs) are a group of conditions whereby parts of the immune system are missing or dysfunctional. Once thought to primarily be a pediatric disorder, it is now estimated that more than 50% of worldwide incident IEI cases are ...
Wang JJF, Dhir A, Hildebrand KJ, Turvey SE, Schellenberg R, Chen LYC, Pourshahnazari P, Biggs CM.   +7 more
europepmc   +4 more sources

Editorial: Immune dysregulation in inborn errors of immunity. [PDF]

Front Pediatr, 2023
Wu EY, Shahlaee AH, Kwan M.
europepmc   +4 more sources

Endocrinopathies in Inborn Errors of Immunity [PDF]

Frontiers in Immunology, 2021
Inborn errors of immunity (IEI), caused by hereditary or genetic defects, are a group of more than 400 disorders, in which the immune system, including lymphocytes, neutrophils, macrophages, and complements, does not function properly.
Kei Takasawa, Hirokazu Kanegane, Kenichi Kashimada, Tomohiro Morio   +3 more
doaj   +3 more sources

Epigenetic Alterations in Inborn Errors of Immunity [PDF]

Journal of Clinical Medicine, 2022
The epigenome bridges environmental factors and the genome, fine-tuning the process of gene transcription. Physiological programs, including the development, maturation and maintenance of cellular identity and function, are modulated by intricate ...
Andrea Riccio, Antonio De Rosa, Chiara Nannola, Claudio Pignata, Cristina Moracas, Elisabetta Toriello, Emilia Cirillo, Emma Coppola, Francesca Cillo, Giuliana Giardino, Laura Pignata, Nicola Brunetti-Pierri, Roberta Romano   +12 more
core   +7 more sources

Inborn errors of immunity and related microbiome

Frontiers in Immunology, 2022
Inborn errors of immunity (IEI) are characterized by diverse clinical manifestations that are dominated by atypical, recurrent, chronic, or severe infectious or non-infectious features, including autoimmunity, lymphoproliferative disease, granulomas, and/
Raja Hazime, Raja Hazime, Fatima-Ezzohra Eddehbi, Saad El Mojadili, Nadia Lakhouaja, Ikram Souli, Abdelmouïne Salami, Bouchra M’Raouni, Imane Brahim, Mohamed Oujidi, Morad Guennouni, Ahmed Aziz Bousfiha, Ahmed Aziz Bousfiha, Brahim Admou, Brahim Admou   +14 more
doaj   +3 more sources

Inborn errors of immunity with eosinophilia

Allergology International, 2021
Monogenic diseases of the immune system, also known as inborn errors of immunity (IEIs), are caused by single-gene mutations and result in immune deficiency and dysregulation.
Keisuke Okamoto, Tomohiro Morio
doaj   +4 more sources

HPV-Related Skin Phenotypes in Patients with Inborn Errors of Immunity [PDF]

Pathogens, 2022
Patients with inborn errors of immunity (IEI) are prone to develop infections, either due to a broad spectrum of pathogens or to only one microbe. Since skin is a major barrier tissue, cutaneous infections are among the most prevalent in patients with ...
Assiya El Kettani, Fatima Ailal, Jalila El Bakkouri, Khalid Zerouali, Vivien Béziat, Emmanuelle Jouanguy, Jean-Laurent Casanova, Ahmed Aziz Bousfiha   +7 more
doaj   +2 more sources

Monogenic Adult-Onset Inborn Errors of Immunity [PDF]

Frontiers in Immunology, 2021
Inborn errors of immunity (IEI) are a heterogenous group of disorders driven by genetic defects that functionally impact the development and/or function of the innate and/or adaptive immune system.
Frederik Staels, Frederik Staels, Tom Collignon, Albrecht Betrains, Albrecht Betrains, Margaux Gerbaux, Margaux Gerbaux, Mathijs Willemsen, Mathijs Willemsen, Stephanie Humblet-Baron, Adrian Liston, Adrian Liston, Steven Vanderschueren, Steven Vanderschueren, Rik Schrijvers, Rik Schrijvers   +15 more
doaj   +4 more sources

Treosulfan-based conditioning for inborn errors of immunity [PDF]

Therapeutic Advances in Hematology, 2021
Inborn errors of immunity (IEI) are inherited disorders that lead to defects in the development and/or function of the immune system. The number of disorders that can be treated by haematopoietic stem-cell transplantation (HSCT) has increased rapidly ...
Mary A. Slatter, Andrew R. Gennery
doaj   +4 more sources

Inborn Errors of Immunity Presenting with Early-Onset Severe Atopy. [PDF]

Medicina (Kaunas)
Inborn errors of immunity (IEIs), also known as primary immunodeficiencies, are a group of genetic disorders affecting the development and function of the immune system.
Chuleerarux N, Makkoukdji N, Satnarine T, Kuhn JE, Nopsopon T, Valyasevi P, Schmidt FB, Kleiner G, Gans M.   +8 more
europepmc   +2 more sources