Results 11 to 20 of about 8,524 (262)
Dendritic cells in inborn errors of immunity [PDF]
Frontiers in Immunology, 2023 Dendritic cells (DCs) are crucial cells for initiating and maintaining immune response. They play critical role in homeostasis, inflammation, and autoimmunity.
Sudhir Gupta, Anshu Agrawal
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Repercussions of inborn errors of immunity on growth
Jornal de Pediatria (Versão em Português), 2019 Objectives: This study aimed to review the literature on the repercussions of the different inborn errors of immunity on growth, drawing attention to the diagnosis of this group of diseases in patients with growth disorders, as well as to enable the ...
Ekaterini Simões Goudouris +2 more
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Inborn errors of immunity (primary immunodeficiencies)
Allergy, Asthma & Clinical ImmunologyPrimary immunodeficiencies (PID), now often referred to as inborn errors of immunity (IEI), are a large heterogeneous group of disorders that result from deficiencies in immune system development and/or function.
Vy H. D. Kim +4 more
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Inborn errors of immunity with eosinophilia
Allergology International, 2021 Monogenic diseases of the immune system, also known as inborn errors of immunity (IEIs), are caused by single-gene mutations and result in immune deficiency and dysregulation.
Keisuke Okamoto, Tomohiro Morio
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Visceral Leishmaniasis Revealing Undiagnosed Inborn Errors of Immunity
Revista da Sociedade Brasileira de Medicina Tropical, 2023 Visceral Leishmaniasis (VL) is a potentially fatal disease and may be associated with primary or acquired immunodeficiencies. There are few reports, in the literature, of inborn errors of immunity.
Daniel Gleison Carvalho +3 more
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Nature and nurture: understanding phenotypic variation in inborn errors of immunity [PDF]
Frontiers in Cellular and Infection Microbiology, 2023 The overall disease burden of pediatric infection is high, with widely varying clinical outcomes including death. Among the most vulnerable children, those with inborn errors of immunity, reduced penetrance and variable expressivity are common but poorly
Morgan Similuk, Taco Kuijpers
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Inborn Errors of Immunity and Autoimmune Disease
The Journal of Allergy and Clinical Immunology: In Practice, 2023 Autoimmunity may be a manifestation of inborn errors of immunity, specifically as part of the subgroup of primary immunodeficiency known as primary immune regulatory disorders. However, although making a single gene diagnosis can have important implications for prognosis and management, picking patients to screen can be difficult, against a background ...
Paul Edgar Gray, Clementine David
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Inborn Errors of Immunity in Apoptosis
Frontiers in Bioscience-LandmarkInborn errors of immunity (IEIs) are a group of more than 485 disorders that impair immune development and function with variable reported incidence, severity, and clinical phenotypes.
Nadia Makkoukdji +6 more
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Epigenetic Alterations in Inborn Errors of Immunity [PDF]
Journal of Clinical Medicine, 2022 The epigenome bridges environmental factors and the genome, fine-tuning the process of gene transcription. Physiological programs, including the development, maturation and maintenance of cellular identity and function, are modulated by intricate epigenetic changes that encompass DNA methylation, chromatin remodeling, histone modifications and RNA ...
Romano R. +12 more
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Atopic manifestations of inborn errors of immunity [PDF]
Current Opinion in Allergy & Clinical Immunology, 2023 Purpose of review Allergy and atopic features are now well recognized manifestations of many inborn errors of immunity (IEI), and indeed may be the hallmark in some, such as DOCK8 deficiency. In this review, we describe the current IEI associated with atopy, using a comprehensive literature search and updates from the IUIS ...
Sams, Laura +4 more
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