Results 21 to 30 of about 15,568 (286)

Repercussions of inborn errors of immunity on growth

Jornal de Pediatria (Versão em Português), 2019
Objectives: This study aimed to review the literature on the repercussions of the different inborn errors of immunity on growth, drawing attention to the diagnosis of this group of diseases in patients with growth disorders, as well as to enable the ...
Ekaterini Simões Goudouris, Gesmar Rodrigues Silva Segundo, Cecilia Poli   +2 more
doaj   +7 more sources

Epigenetic Alterations in Inborn Errors of Immunity [PDF]

Journal of Clinical Medicine, 2022
The epigenome bridges environmental factors and the genome, fine-tuning the process of gene transcription. Physiological programs, including the development, maturation and maintenance of cellular identity and function, are modulated by intricate ...
Andrea Riccio, Antonio De Rosa, Chiara Nannola, Claudio Pignata, Cristina Moracas, Elisabetta Toriello, Emilia Cirillo, Emma Coppola, Francesca Cillo, Giuliana Giardino, Laura Pignata, Nicola Brunetti-Pierri, Roberta Romano   +12 more
core   +7 more sources

Editorial: Immune dysregulation in inborn errors of immunity

Frontiers in Pediatrics, 2023
Eveline Y. Wu, Eveline Y. Wu, Amir H. Shahlaee, Mildred Kwan   +3 more
doaj   +3 more sources

Immune dysfunction in inborn errors of immunity causing malignancies [PDF]

Expert Review of Clinical Immunology, 2021
In recent years, numerous new genetic reasons for human inborn errors of immunity (IEI) have been identified [1,2].
Baris, Safa, Kolukisa, Burcu
openaire   +3 more sources

The Ever-Increasing Array of Novel Inborn Errors of Immunity : an Interim Update by the IUIS Committee [PDF]

, 2021
The most recent updated classification of inborn errors of immunity/primary immunodeficiencies, compiled by the International Union of Immunological Societies Expert Committee, was published in January 2020.
Al-Herz, Waleed, Bousfiha, Aziz, Cunningham-Rundles, Charlotte, Franco, Jose Luis, Holland, Steven M., Klein, Christoph, Meyts, Isabelle, Morio, Tomohiro, Oksenhendler, Eric, Picard, Capucine, Puck, Jennifer, Puel, Anne, Seppänen, Mikko R. J., Somech, Raz, Su, Helen C., Sullivan, Kathleen E., Tangye, Stuart G., Torgerson, Troy R.   +17 more
core   +2 more sources

Disseminated mycobacterial infections after tumor necrosis factor inhibitor use, revealing inborn errors of immunity

International Journal of Infectious Diseases, 2023
Tumor necrosis factor-a inhibitors can be associated with increased risk of infections, particularly reactivation of latent tuberculosis or nontuberculous mycobacterium (NTM). However, because disseminated NTM is rare, inborn errors of immunity should be
Jacqueline D. Squire, Claudia R. Libertin, Harry Powers, Jared Nelson, Lisa Brumble, Federico R. Laham, Anahita Agharahimi, Alexandra F. Freeman, Jennifer W. Leiding   +8 more
doaj   +1 more source

DNA replication–associated inborn errors of immunity

Journal of Allergy and Clinical Immunology, 2023
Inborn errors of immunity are a heterogeneous group of monogenic immunologic disorders caused by mutations in genes with critical roles in the development, maintenance, or function of the immune system. The genetic basis is frequently a mutation in a gene with restricted expression and/or function in immune cells, leading to an immune disorder. Several
Willemsen, Mathijs, Staels, Frederik, Gerbaux, Margaux, Neumann, Julika, Schrijvers, Rik, Meyts, Isabelle, Humblet-Baron, Stephanie, Liston, Adrian   +7 more
openaire   +3 more sources

Liver immunity, autoimmunity, and inborn errors of immunity

World Journal of Hepatology, 2023
The liver is the front line organ of the immune system. The liver contains the largest collection of phagocytic cells in the body that detect both pathogens that enter through the gut and endogenously produced antigens. This is possible by the highly developed differentiation capacity of the liver immune system between self-antigens or non-self ...
Parlar, Yavuz Emre, Ayar, Sefika Nur, Cagdas, Deniz, Balaban, Yasemin H   +3 more
openaire   +2 more sources

Visceral Leishmaniasis Revealing Undiagnosed Inborn Errors of Immunity

Revista da Sociedade Brasileira de Medicina Tropical, 2023
Visceral Leishmaniasis (VL) is a potentially fatal disease and may be associated with primary or acquired immunodeficiencies. There are few reports, in the literature, of inborn errors of immunity.
Daniel Gleison Carvalho, Dewton de Moraes Vasconcelos, Andreia Cristiane Rangel Santos, Jose Angelo Lauletta Lindoso   +3 more
doaj   +1 more source

Atopic manifestations of inborn errors of immunity

Current Opinion in Allergy & Clinical Immunology, 2023
Purpose of review Allergy and atopic features are now well recognized manifestations of many inborn errors of immunity (IEI), and indeed may be the hallmark in some, such as DOCK8 deficiency. In this review, we describe the current IEI associated with atopy, using a comprehensive literature search and updates from the IUIS ...
Sams, Laura, Wijetilleka, Sonali, Ponsford, Mark, Gennery, Andrew, Jolles, Stephen   +4 more
openaire   +2 more sources