Results 21 to 30 of about 7,022,792 (370)
Current Opinion in Rheumatology, 2002 Inclusion body myositis (IBM) is an inflammatory myopathy with distinctive clinicopathologic features. The etiology of IBM remains elusive. The immune-mediated basis for this disease has been challenged by evidence implicating a number of divergent etiologic factors.
Rabi, Tawil, Robert C, Griggs
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Inclusion Bodies in Ionic Liquids
Liquids, 2023 The pivotal role of proteins in pharmaceuticals is challenged by stability issues, making the study of inclusion bodies—a source of insoluble protein aggregates—increasingly relevant.
András Szabadi +3 more
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Neurologic Clinics, 2012 The idiopathic inflammatory myopathies (IIMs) are a heterogeneous group of rare disorders that share many similarities. In addition to sporadic inclusion body myositis (IBM), these include dermatomyositis, polymyositis, and autoimmune necrotizing myopathy. IBM is the most common IIM after age 50 years.
Mazen M, Dimachkie, Richard J, Barohn
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mBio, 2020 Respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract illness in infants, elderly, and immunocompromised people. No vaccine or efficient antiviral treatment is available against this virus.
M. Galloux +5 more
semanticscholar +1 more source
Autopsy Case Reports, 2023 Inclusion body fibromatosis is a benign, often locally recurring myofibroblastic tumor with distinctive intracytoplasmic eosinophilic inclusions. In 1965, Reye1 was the first to document this entity through a series of 6 cases of digital fibrous tumors of childhood, where he observed intracytoplasmic inclusion bodies.
Elgiva Iangngap +4 more
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Bacterial inclusion bodies contain amyloid-like structure. [PDF]
PLoS Biology, 2008 Protein aggregation is a process in which identical proteins self-associate into imperfectly ordered macroscopic entities. Such aggregates are generally classified as amorphous, lacking any long-range order, or highly ordered fibrils. Protein fibrils can
Lei Wang +4 more
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Journal of Virology, 2020 Many viruses replicate almost entirely in the cytoplasm of infected cells; however, how these pathogens are able to compartmentalize their life cycle to provide favorable conditions for replication and to avoid the litany of antiviral detection ...
Fatoumatta Jobe +4 more
semanticscholar +1 more source
Coiled-coil inspired functional inclusion bodies
Microbial Cell Factories, 2020 Background Recombinant protein expression in bacteria often leads to the formation of intracellular insoluble protein deposits, a major bottleneck for the production of soluble and active products.
Marcos Gil-Garcia +2 more
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Applied Microbiology and Biotechnology, 2020 Bacterial inclusion bodies (IBs) have long been considered as inactive, unfolded waste material produced by heterologous overexpression of recombinant genes.
Vera D. Jäger +7 more
semanticscholar +1 more source
Kinetics of inclusion body formation and its correlation with the characteristics of protein aggregates in Escherichia coli. [PDF]
PLoS ONE, 2012 The objective of the research was to understand the structural determinants governing protein aggregation into inclusion bodies during expression of recombinant proteins in Escherichia coli.
Arun K Upadhyay +3 more
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