Results 61 to 70 of about 1,673,307 (292)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Unfriendly incubators [PDF]

Archives of Disease in Childhood - Fetal and Neonatal Edition, 1994
DELLAGRAMMATICAS, HD, PAPAGEORGIOU, A
openaire   +3 more sources

Synergistic blend: Curcumin-loaded silver nanoparticles synthesized from Talaromyces atroroseus pigment for bio evaluation

Plant Nano Biology
Metallic silver, particularly in the form of silver nanoparticles (AgNPs), has gained renewed attention as a powerful antimicrobial solution. In the present investigation, AgNP was synthesized using pigments produced by Talaromyces atroroseus, and ...
R. Aakash, Kavyarathna, Nagananda G S, Kavya T R, Roopa Reddy, K.U. Minchitha, S. Swetha, Sandeep Suryan   +7 more
doaj   +1 more source

Microbial Degradation of Lignocellulose in Empty Fruit Bunch at Various Incubation Time

, 2022
Noverando Rafiel Angelo, Rudiyansyah Rudiyansyah, Gusrizal Gusrizal   +2 more
openalex   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Estimation and prediction method of lithium battery state of health based on ridge regression and gated recurrent unit

IET Energy Systems Integration
The health state of lithium‐ion batteries is influenced by the operating conditions of energy storage stations and battery characteristics. It is challenging to obtain real‐time characterisation parameters like maximum discharge capacity and internal ...
Ziwei Dai, Aikui Li, Wei Sun, Shenwu Zhang, Hao Zhou, Ren Rao, Quan Luo   +6 more
doaj   +1 more source

Discriminant canonical analysis as a tool to determine traces of endangered native hen breed introgression through egg hatchability phenomics [PDF]

Animal Bioscience
Objective The main objective of this study was to develop a pipeline to detect phenogenomic introgression across different multivariety breeds and to validate such classification focusing on external egg and hatchability-related traits using a ...
Antonio González Ariza, Francisco Javier Navas González, Ander Arando Arbulu, José Manuel León Jurado, Juan Vicente Delgado Bermejo, María Esperanza Camacho Vallejo   +5 more
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

New horizons of microphysiological systems: India forging its path in human-relevant research

Biology Open, 2023
Surat Parvatam, Kasturi Mahadik, Anushka Banerjee, Kadambari Patil, V. Radha, Madhusudhana Rao   +5 more
doaj   +1 more source