Results 61 to 70 of about 2,629,038 (335)

Electrochemical studies on Ni, Co & Ni/Co-MOFs for high-performance hybrid supercapacitors

Materials Research Express, 2020
Metal-organic framework (MOF) of Ni-MOF, Co-MOF, and Ni/Co-MOF were synthesized by a facile hydrothermal method using Trimesic acid as structure directing linker. The physico-chemical properties of the synthesized MOFs were characterized by P-XRD (powder
M G Radhika, B Gopalakrishna, K Chaitra, Lakshminarayana Kudinalli Gopalakrishna Bhatta, Krishna Venkatesh, M K Sudha Kamath, N Kathyayini   +6 more
doaj   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

FEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican, Yara Nabawi, William Hongyu Zhang, Dunja Petrovic, Markus Wehrmann, Sara Muñoz‐García, Seda Koyuncu, David Vilchez   +7 more
wiley   +1 more source

Amentoflavone Affects Epileptogenesis and Exerts Neuroprotective Effects by Inhibiting NLRP3 Inflammasome

Frontiers in Pharmacology, 2019
Brain inflammation is one of the main causes of epileptogenesis, a chronic process triggered by various insults, including genetic or acquired factors that enhance susceptibility to seizures. Amentoflavone, a naturally occurring biflavonoid compound that
Shikuo Rong, Ding Wan, Ding Wan, Yayun Fan, Shenhai Liu, Kuisheng Sun, Junming Huo, Peng Zhang, Xinxiao Li, Xiaoliang Xie, Feng Wang, Feng Wang, Tao Sun, Tao Sun   +13 more
doaj   +1 more source

Evolutionary dynamics of incubation periods [PDF]

, 2017
The incubation period of a disease is the time between an initiating pathologic event and the onset of symptoms. For typhoid fever, polio, measles, leukemia and many other diseases, the incubation period is highly variable. Some affected people take much
Ottino-Loffler, Bertrand, Scott, Jacob G., Strogatz, Steven H.   +2 more
core   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

FEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura, Lixiang Wang, Nao Hasuzawa, Ayako Nagayama, Sawako Moriyama, Kenji Ashida, Yoshinori Moriyama, Masatoshi Nomura, Ken Yamamoto   +8 more
wiley   +1 more source

Flexible parental care: Uniparental incubation in biparentally incubating shorebirds [PDF]

Scientific Reports, 2017
Recent findings suggest that relative investment of females and males into parental care depends on the population’s adult sex-ratio. For example, all else being equal, males should be the more caring sex if the sex ratio is male biased. Whether such outcomes are evolutionary fixed (i.e.
Bulla, Martin, Prüter, Hanna, Vitnerová, Hana, Tijsen, Wim, Sládeček, Martin, Alves, José A., Gilg, Olivier, Kempenaers, Bart   +7 more
openaire   +5 more sources

The role of incubator classification on performance of incubators in Kenya.

International Journal of Research in Business and Social Science (2147- 4478), 2021
The study sought to assess the importance of classifying incubators based on the programs offered for optimum performance. Client selection criteria were assessed through three constructs namely: models that fit program goals, uniqueness of ideas, and standard selection tool.
Miriti Jane Kinya, Kenneth Lawrance Wanjau, Nyagweth Ebenezer Odeyo   +2 more
openaire   +3 more sources

H2S paper strip method - A bacteriological test for faecal coliforms in drinking water at various temperatures [PDF]

, 1998
Epidemics arising from waterborne diseases are a global health problem. Faecal contamination of drinking water is the main cause of these outbreaks. According to WHO (1996) for drinking water to be safe, a 100 ml sample should not contain any coliform ...
Gibbs, R., Ho, G., Mathew, K., Pillai, J.   +3 more
core   +1 more source

The effect of experimental hyperoxia on erythrocytes’ oxygen-transport function [PDF]

, 2018
The aim of this study was to investigate the effect of hyperoxia, calcium ions and pH value on the composition of major phospholipids in human erythrocyte membranes and erythrocytes’ oxygen-transport function. To create a model of hyperoxia, we saturated
Alexander Alexandrovich Moskovkin, Alexander Yurievich Tychkov, Anastasia Nikolaevna Kukina, Anastasia Yurievna Samonova, Bligh EA, Borza C, Dobrotyna NA, Drgová A, Elvira Sergeevna Revina, Gavrilov VB, Gavrilov VB, Igor Pavlovich Grunyushkin, Jean-Christophe Bourdon, Litvitskiy PF, Marangoni AG, Marinetti GV, Morrison WR, Natalia Vasilevna Gromova, Nikolai Zhelev, Novitskiy VV, Sikorski AF, Takakuwa Y, Vasil'yeva YEM, Vercaеmst L, Victor Vasilevich Revin, Vlasov AP   +25 more
core   +4 more sources

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

FEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri, Andrea Lapucci, Giuseppe Orsomando, Nadia Raffaelli, Alberto Chiarugi, Daniela Buonvicino   +5 more
wiley   +1 more source