Results 1 to 10 of about 1,672 (143)

Global Variation in Escherichia coli mcr-1 Genes and Plasmids from Animal and Human Genomes Following Colistin Usage Restrictions in Livestock [PDF]

Antibiotics
Antimicrobial resistance (AMR) is a significant global health threat, with multidrug-resistant (MDR) bacterial clones becoming a major concern. Polymyxins, especially colistin, have reemerged as last-resort treatments for MDR Gram-negative infections ...
Biel Garcias, Mayra Alejandra Flores, Mercedes Fernández, William Monteith, Ben Pascoe, Samuel K. Sheppard, Marga Martín, Martí Cortey, Laila Darwich   +8 more
doaj   +6 more sources

First detection and genomic analysis of mcr-1-positive Salmonella Infantis isolated from a broiler production system in the United Arab Emirates [PDF]

Frontiers in Veterinary Science
This study reports the first detection of mcr-1.1-mediated colistin resistance in Salmonella enterica serovar Infantis from a commercial broiler farm in the United Arab Emirates (UAE). Two S.
Ihab Habib, Mohamed-Yousif Ibrahim Mohamed, Glindya Bhagya Lakshmi, Hassan Mohamed Al Marzooqi, Hanan Sobhy Afifi, Mohamed Gamal Shehata, Mohamed Gamal Shehata, Mohammed Elbediwi, Mohammed Elbediwi   +8 more
doaj   +5 more sources

Worldwide Disseminated IncX4 Plasmid Carrying mcr-1 Arrives to Wild Mammal in Portugal [PDF]

Microbiology Spectrum, 2022
The mcr-1 gene spread is worldwide recognized as a public health threat at multidrug-resistant infections therapy level. Here, we report for the first time, to the best of our knowledge, the detection of the globally distributed IncX4 plasmid carrying ...
Josman Dantas Palmeira, Mónica V. Cunha, Helena Ferreira, Carlos Fonseca, Rita Tinoco Torres   +4 more
doaj   +3 more sources

Case Report: Transferable IncX4 plasmid carrying mcr-1 in colistin-resistant Escherichia coli from a healthy pet dog in South Korea [PDF]

Frontiers in Veterinary Science
Colistin resistance mediated by the plasmid-borne mcr-1 gene presents a significant challenge in both human and veterinary medicine. While colistin-resistant bacteria have been reported in food-producing animals and humans, mcr-1-harboring strains remain
Jae Young Oh, Jae Young Oh, Su Min Kwak, Joo Yeol Kim, Joo Yeol Kim, Woong-Bin Ro, Kwang Jun Lee, Jong-Chan Chae, Jong-Chan Chae   +8 more
doaj   +2 more sources

Tracking Global Transmission Dynamics of the Plasmid-Mediated mcr Gene: A Genomic Epidemiological Analysis [PDF]

Microorganisms
The emergence and spread of mobile colistin resistance (mcr) genes pose a significant challenge in controlling multidrug-resistant Gram-negative pathogens.
Jinzhao Long, Xin Wang, Mengyue Liu, Jie Wu, Haiyan Yang, Shuaiyin Chen, Guangcai Duan   +6 more
doaj   +2 more sources

Inhibitory effects of benzyl isothiocyanate on widespread mcr-1-harbouring IncX4 plasmid transfer [PDF]

Scientific Reports
The global dissemination of mobile colistin resistance (mcr) genes represents a significant public health threat due to colistin’s critical role in treating multidrug-resistant (MDR) bacterial infections. We identified high rates of carbapenem resistance
Sirirat Luk-In, Kamonrat Phopin, Sasina Bangmuangngam, Tanittha Chatsuwan, Dhammika Leshan Wannigama, Aye Mya Sithu Shein, Rongpong Plongla, Ratana Lawung, Sakda Yainoy, Warawan Eiamphungporn, Chawalit Chatupheeraphat, Tanawut Tantimongcolwat   +11 more
doaj   +2 more sources

One Health at Risk: Plasmid-Mediated Spread of mcr-1 Across Clinical, Agricultural, and Environmental Ecosystems [PDF]

Antibiotics
The global dissemination of plasmid-mediated mcr genes, which confer resistance to the last-resort antibiotic colistin, represents a critical public health challenge driven by the interplay of clinical, agricultural, and environmental factors.
Abdelaziz Touati, Nasir Adam Ibrahim, Assia Mairi, Hassina Kirat, Nosiba S. Basher, Takfarinas Idres   +5 more
doaj   +2 more sources

The Co-Existence of mcr-1.1 and mcr-3.5 in Escherichia coli Isolated from Clinical Samples in Thailand [PDF]

Antibiotics
The emergence of colistin resistance poses a significant threat to its efficacy as a last-line treatment against multidrug-resistant Gram-negative bacterial infections.
Panida Nobthai, Sirigade Ruekit, Dutsadee Peerapongpaisarn, Prawet Sukhchat, Brett E. Swierczewski, Nattaya Ruamsap, Paphavee Lertsethtakarn   +6 more
doaj   +2 more sources

Increased kanamycin-resistant Salmonella Schwarzengrund, serovar changing and antimicrobial susceptibility of Salmonella enterica from broiler chickens in Kagoshima, Japan between 2019 and 2023 [PDF]

BMC Veterinary Research
Background This study investigated the prevalence of Salmonella, determined the minimum inhibitory concentrations (MICs) of antimicrobials, and examined antimicrobial resistance genes and plasmids in Salmonella strains from broiler chickens in Kagoshima ...
George J. Sanga, Saki Hiramoto, Rika Miyajima, Vu Minh Duc, Takeshi Obi, Hiroaki Shigemura, Takehisa Chuma   +6 more
doaj   +2 more sources

First three Escherichia coli isolates harbouring mcr-1 in Uruguay [PDF]

Journal of Global Antimicrobial Resistance, 2020
Objective: This report described the first Escherichia coli (E. coli) isolates harbouring mcr-1 in Uruguay. Methods: Three E. coli isolates were obtained from blood, urine and rectal swabs from different patients in two hospitals.
Romina Papa-Ezdra, Fabio Grill Diaz, Mariela Vieytes, Virginia García-Fulgueiras, Leticia Caiata, Pablo Ávila, María Brasesco, Inés Christophersen, Nicolás F. Cordeiro, Gabriela Algorta, Antonio Galiana, Rafael Vignoli   +11 more
doaj   +3 more sources