Journal of Global Antimicrobial Resistance: IncX4 plasmids are one of the most epidemiologically successful vehicles for mcr-1 spread. Here we found that the IncX4 plasmids carried two different replication proteins encoded by genes pir-1 and pir-2, respectively, but mcr-1 was only carried by ...
Lingxian Yi +7 more
doaj +5 more sources
Withdrawal of Colistin Reduces Incidence of mcr-1-Harboring IncX4-Type Plasmids but Has Limited Effects on Unrelated Antibiotic Resistance [PDF]
Pathogens, 2021 The global dissemination of plasmid-mediated colistin resistance gene mcr and its variants have posed a great threat to public health. Therefore, the Chinese government banned the use of colistin as a feed additive in livestock in April 2017.
Zunfang Tu +5 more
doaj +3 more sources
Expansion of KPC-producing klebsiella pneumoniae with various mgrB-mutations giving rise to colistin-resistance:the role of ISL3 on plasmids [PDF]
, 2018 BACKGROUND: mcr-1 has been reported as first plasmid gene to confer colistin-resistance. In KPC-producing Klebsiella pneumoniae (KPC-KP) isolates, however, colistin resistance is rapidly emerging through other mechanisms. This is frequently the result of
Barnini, Simona +8 more
core +1 more source
Draft Genome Sequence of NDM-5-Producing Escherichia coli Sequence Type 648 and Genetic Context of blaNDM-5 in Australia [PDF]
, 2015 We report here the draft genome sequence of uropathogenic Escherichia\ua0coli sequence type 648 (ST648) possessing blaNDM-5 from a 55-year-old female in Australia with a history of travel to India.
Caffery, Michael +4 more
core +1 more source
Serum bactericidal activity of colistin and azidothymidine combinations against mcr-1 positive colistin-resistant Escherichia coli. [PDF]
, 2018 To examine the serum bactericidal activity of colistin-sulphate (CS) and azidothymidine (AZT) combinations, time-kill curves were performed in native and heat-inactivated human serum with five colistin-resistant and four colistin-susceptible Gram ...
Coates, A +4 more
core +1 more source
First detection of mcr-1-producing Escherichia coli in Greece
Journal of Global Antimicrobial Resistance, 2022 : Objectives: In this communication, we describe the emergence of the mcr-1 colistin resistance gene in a blaCTX-M-32 extended-spectrum–β-lactamase-producing Escherichia coli isolate recovered from a pediatric patient in Greece.
Efthymia Protonotariou +10 more
doaj +1 more source
Prevalence and characterization of hybrid blaCTX-M among Escherichia coli isolates from livestock and other animals [PDF]
, 2015 This study investigated 248 extended-spectrum β-lactamase-producing Escherichia coli isolates from 2012 to 2013 for hybrid blaCTX-M genes. blaCTX-M genes were detected in 228 isolates of which 14 isolates were hybrid blaCTX-M positive (6 blaCTX-M-123, 6 ...
Chow, KH +6 more
core +1 more source
Emerging Infectious Diseases, 2017 Escherichia coli Ec36 was recovered from a patient in Portugal after treatment with meropenem and colistin. Besides an IncF plasmid with Tn1441d-blaKPC-3, already reported in clinical strains in this country, E. coli Ec36 co-harbored an IncX4::mcr-1 gene.
Marta Tacão +6 more
doaj +1 more source
Identification and characterization of a novel incompatibility group X3 plasmid carrying blaNDM-1 in Enterobacteriaceae isolates with epidemiological links to multiple geographical areas in China [PDF]
, 2012 postprin
Cheng, VCC +9 more
core +1 more source
Is the Evolution of Salmonella enterica subsp. enterica Linked to Restriction-Modification Systems? [PDF]
, 2016 Salmonella enterica subsp. enterica bacteria are highly diverse foodborne pathogens that are subdivided into more than 1,500 serovars. The diversity is believed to result from mutational evolution, as well as intra- and interspecies recombination that ...
Frank M. Aarestrup +7 more
core +3 more sources