Results 31 to 40 of about 1,638 (164)

Rapid Increase in the IS26-Mediated cfr Gene in E. coli Isolates with IncP and IncX4 Plasmids and Co-Existing cfr and mcr-1 Genes in a Swine Farm [PDF]

Pathogens, 2021
This paper aimed to investigate the molecular epidemiological features of the cfr gene in E. coli isolates in a typical swine farm during 2014–2017. A total of 617 E. coli isolates were screened for the cfr gene using PCR amplification.
Zhenbao Ma, Jiao Liu, Lin Chen, Xiaoqin Liu, Wenguang Xiong, Jian-Hua Liu, Zhenling Zeng   +6 more
doaj   +3 more sources

Coupling antitoxins and blue/white screening with parAB/resolvase mutation as a strategy for Salmonella spp. plasmid curing [PDF]

Microbiology Spectrum
Despite the dissemination of multidrug resistance plasmids, including those carrying virulence genes in Salmonella spp., efficient plasmid curing tools are lacking.
Dereje D. Gudeta, Shaohua Zhao, Nesreen Aljahdali, Steven L. Foley   +3 more
doaj   +2 more sources

First Report of Colistin-Resistant Escherichia coli Carrying mcr-1 IncI2(delta) and IncX4 Plasmids from Camels (Camelus dromedarius) in the Gulf Region. [PDF]

Antibiotics
Addressing the emergence of antimicrobial resistance (AMR) poses a significant challenge in veterinary and public health. In this study, we focused on determining the presence, phenotypic background, and genetic epidemiology of plasmid-mediated colistin ...
Ahmed, Amal, AlHosani, Aysha, AlShehhi, Mirah, Anes, Febin, Ghazawi, Akela, Habib, Ihab, Hays, John, Khan, Mushtaq, Manzoor, Ashrat, Strepis, Nikolaos, Wani, Nisar A., Yaaqeib, Dana   +11 more
core   +7 more sources

IncX4 plasmid carrying the new mcr-1.9 gene variant in a CTX-M-8-producing Escherichia coli isolate recovered from swine [PDF]

Frontiers in Microbiology, 2019
We studied a commensal colistin-resistant Escherichia coli isolated from a swine cecum sample collected at a slaughter, in Portugal. Antimicrobial susceptibility phenotype of E.
Caniça, Manuela, Clemente, Lurdes, Ferreira, Eugénia, Manageiro, Vera, Romão, Raquel, Silva, Catarina, Vieira, Luís   +6 more
core   +3 more sources

Global Variation in <i>Escherichia coli mcr-1</i> Genes and Plasmids from Animal and Human Genomes Following Colistin Usage Restrictions in Livestock. [PDF]

Antibiotics (Basel)
Antimicrobial resistance (AMR) is a significant global health threat, with multidrug-resistant (MDR) bacterial clones becoming a major concern. Polymyxins, especially colistin, have reemerged as last-resort treatments for MDR Gram-negative infections ...
Garcias B, Flores MA, Fernández M, Monteith W, Pascoe B, Sheppard SK, Martín M, Cortey M, Darwich L.   +8 more
europepmc   +4 more sources

Complete nucleotide sequence of cfr-carrying IncX4 plasmid pSD11 from Escherichia coli. [PDF]

Antimicrob Agents Chemother, 2015
ABSTRACT We report the complete nucleotide sequence of a plasmid carrying the multiresistance gene cfr . This plasmid was isolated from an Escherichia coli strain of swine origin in 2011.
Sun J, Deng H, Li L, Chen MY, Fang LX, Yang QE, Liu YH, Liao XP.   +7 more
europepmc   +4 more sources

IncX4 Plasmid Carrying the New mcr-1.9 Gene Variant in a CTX-M-8-Producing Escherichia coli Isolate Recovered From Swine. [PDF]

Front Microbiol, 2019
We studied a commensal colistin-resistant Escherichia coli isolated from a swine cecum sample collected at a slaughter, in Portugal. Antimicrobial susceptibility phenotype of E. coli LV23529 showed resistance to colistin at a minimum inhibitory concentration of 4 mg/L. Whole genome of E. coli LV23529 was sequenced using a MiSeq system and the assembled
Manageiro V, Clemente L, Romão R, Silva C, Vieira L, Ferreira E, Caniça M.   +6 more
europepmc   +5 more sources

A mcr-1-Carrying Conjugative IncX4 Plasmid in Colistin-Resistant Escherichia coli ST278 Strain Isolated From Dairy Cow Feces in Shanghai, China. [PDF]

Front Microbiol, 2018
Enterobacteriaceae, including Escherichia coli, has been shown to acquire the colistin resistance gene mcr-1. A strain of E. coli, EC11, which is resistant to colistin, polymyxin B and trimethoprim-sulfamethoxazole, was isolated in 2016 from the feces of a dairy cow in Shanghai, China.
Bai F, Li X, Niu B, Niu B, Zhang Z, Malakar PK, Liu H, Pan Y, Zhao Y.   +8 more
europepmc   +5 more sources

Colistin resistance plasmids dually enhance bacterial virulence and antibiotic resistance via surface polysaccharide biosynthesis [PDF]

Nature Communications
Plasmids carrying the mobilized colistin-resistance gene mcr-1 are prevalent among multidrug-resistant Gram-negative pathogens, yet their broad impact on bacterial physiology and virulence remains unclear.
Eunbyeol Ahn, Jinshil Kim, Junyao Jiang, Joonbeom Kim, Artur Muszyński, Katarzyna Kasperkiewicz, Hojun Shin, Yingqi Cao, Yejin Soh, Youngjae Park, Christian Heiss, Liyanage Devthilini Pasasum Fernando, Parastoo Azadi, Yang Wang, Byeonghwa Jeon, Sangryeol Ryu   +15 more
doaj   +2 more sources

Plasmid Mediated mcr-1.1 Colistin-Resistance in Clinical Extraintestinal Escherichia coli Strains Isolated in Poland

Frontiers in Microbiology, 2021
Objectives: The growing incidence of multidrug-resistant (MDR) bacteria is an inexorable and fatal challenge in modern medicine. Colistin is a cationic polypeptide considered a “last-resort” antimicrobial for treating infections caused by MDR Gram ...
Piotr Majewski, Anna Gutowska, David G. E. Smith, Tomasz Hauschild, Paulina Majewska, Tomasz Hryszko, Dominika Gizycka, Boguslaw Kedra, Jan Kochanowicz, Jerzy Glowiński, Justyna Drewnowska, Izabela Swiecicka, Pawel T. Sacha, Piotr Wieczorek, Dominika Iwaniuk, Anetta Sulewska, Radoslaw Charkiewicz, Katarzyna Makarewicz, Agnieszka Zebrowska, Slawomir Czaban, Piotr Radziwon, Piotr Radziwon, Jacek Niklinski, Elzbieta A. Tryniszewska   +23 more
doaj   +1 more source