Results 51 to 60 of about 1,638 (164)

Phylogenomics, epigenomics, virulome and mobilome of Gram‐negative bacteria co‐resistant to carbapenems and polymyxins: a One Health systematic review and meta‐analyses

Environmental Microbiology, Volume 24, Issue 3, Page 1518-1542, March 2022., 2022
Summary Gram‐negative bacteria (GNB) continue to develop resistance against important antibiotics including last‐resort ones such as carbapenems and polymyxins. An analysis of GNB with co‐resistance to carbapenems and polymyxins from a One Health perspective is presented.
Winnie Thabisa Ramaloko, John Osei Sekyere   +1 more
wiley   +1 more source

Role played by the environment in the emergence and spread of antimicrobial resistance (AMR) through the food chain

EFSA Journal, Volume 19, Issue 6, June 2021., 2021
Abstract The role of food‐producing environments in the emergence and spread of antimicrobial resistance (AMR) in EU plant‐based food production, terrestrial animals (poultry, cattle and pigs) and aquaculture was assessed. Among the various sources and transmission routes identified, fertilisers of faecal origin, irrigation and surface water for plant ...
EFSA Panel on Biological Hazards (BIOHAZ), Konstantinos Koutsoumanis, Ana Allende, Avelino Álvarez‐Ordóñez, Declan Bolton, Sara Bover‐Cid, Marianne Chemaly, Robert Davies, Alessandra De Cesare, Lieve Herman, Friederike Hilbert, Roland Lindqvist, Maarten Nauta, Giuseppe Ru, Marion Simmons, Panagiotis Skandamis, Elisabetta Suffredini, Héctor Argüello, Thomas Berendonk, Lina Maria Cavaco, William Gaze, Heike Schmitt, Ed Topp, Beatriz Guerra, Ernesto Liébana, Pietro Stella, Luisa Peixe   +26 more
wiley   +1 more source

Comprehensive Genomic Investigation of Coevolution of mcr genes in Escherichia coli Strains via Nanopore Sequencing

Global Challenges, Volume 5, Issue 3, March 2021., 2021
The evolutionary trajectory of mobile colistin resistance genes and the underlying genomic basis in bacteria are largely unknown after withdrawal of colistin from animal feed additives. This study comprehensively deciphers the genomic landscape after the elimination of mcr genes during bacterial growth under different conditions, highlighting the ...
Ruichao Li, Pengcheng Du, Pei Zhang, Yan Li, Xiaorong Yang, Zhiqiang Wang, Juan Wang, Li Bai   +7 more
wiley   +1 more source

Global phylogenetic analysis of Escherichia coli and plasmids carrying the mcr-1 gene indicates bacterial diversity but plasmid restriction [PDF]

, 2017
To understand the dynamics behind the worldwide spread of the mcr-1 gene, we determined the population structure of Escherichia coli and of mobile genetic elements (MGEs) carrying the mcr-1 gene. After a systematic review of the literature we included 65
Arcilla, M.S. (Maris), Bootsma, M.C.J. (Martin), Genderen, P.J.J. (Perry) van, Goorhuis, A. (Abraham), Grobusch, M.P. (Martin P.), Hattem, J.M. (Jarne) van, Jong, M.D. (Menno) de, Matamoros, S. (Sebastien), Melles, D.C. (Damian), Molhoek, N. (Nicky), Oude Lashof, A. (A.), Penders, J. (John), Schultsz, C. (Constance), Stobberingh, E.E. (Ellen), Thi Hoa, N. (Ngo), Verbrugh, H.A. (Henri), Vinh, T.N. (Trung Nguyen), Willemse, N. (Niels)   +17 more
core   +6 more sources

Prevalence and Traits of Mobile Colistin Resistance Gene Harbouring Isolates from Different Ecosystems in Africa

BioMed Research International, Volume 2021, Issue 1, 2021., 2021
The mobile colistin resistance (mcr) gene threatens the efficacy of colistin (COL), a last‐line antibiotic used in treating deadly infections. For more than six decades, COL is used in livestock around the globe, including Africa. The use of critically important antimicrobial agents, like COL, is largely unregulated in Africa, and many other factors ...
Madubuike Umunna Anyanwu, Charles Odilichukwu R. Okpala, Kennedy Foinkfu Chah, Vincent Shodeinde Shoyinka, Mohamed Salah Abbassi   +4 more
wiley   +1 more source

Genetic features of MCR-1-producing colistin-resistant Escherichia coli isolates in South Africa [PDF]

, 2016
A series of colistin-resistant Escherichia coli clinical isolates was recovered from hospitalized and community patients in South Africa. Seven clonally unrelated isolates harbored the mcr-1 gene located on different plasmid backbones.
Brink, Adrian, Coetze, Jennifer, Jayol, Aurélie, Kieffer, Nicolas, Nordmann, Patrice, Poirel, Laurent   +5 more
core   +1 more source

Detection of mcr-1 encoding plasmid-mediated colistin-resistant Escherichia coli isolates from human bloodstream infection and imported chicken meat, Denmark 2015 [PDF]

, 2015
The plasmid-mediated colistin resistance gene, mcr-1, was detected in an Escherichia coli isolate from a Danish patient with bloodstream infection and in five E. coli isolates from imported chicken meat.
Aarestrup, Frank Møller, Agersø, Yvonne, Cavaco, Lina, Hammerum, A. M., Hansen, D. S., Hansen, F., Hasman, H., Hendriksen, Rene S., Kaas, Rolf Sommer, Leekitcharoenphon, Pimlapas, Olesen, B., Skov, R. L., Stegger, M., Zankari, Ea   +13 more
core   +1 more source

NDM-5-Producing Escherichia coli Co-Harboring mcr-1 Gene in Companion Animals in China

Animals, 2022
Carbapenem and colistin are important antibiotics for the treatment of infections caused by multidrug-resistant Gram-negative pathogens. Here, we isolated the blaNDM-5-harboring Escherichia coli in companion animals in healthy or diseased companion ...
Xu Kuang, Runshi Yang, Xinqing Ye, Jian Sun, Xiaoping Liao, Yahong Liu, Yang Yu   +6 more
doaj   +1 more source

Global burden of colistin-resistant bacteria : mobilized colistin resistance genes study (1980-2018) [PDF]

, 2019
Colistin is considered to be an antimicrobial of last-resort for the treatment of multidrug-resistant Gram-negative bacterial infections. The recent global dissemination of mobilized colistin resistance (mcr) genes is an urgent public health threat.
Elbediwi, Mohammed, Fang, Weihuan, Feng, Youjun, Li, Xiaoliang, Li, Yan, Pan, Hang, Paudyal, Narayan, Rajkovic, Andreja, Rankin, Shelley C., Xie, Shaohua, Yue, Min   +10 more
core   +1 more source

Plasmidome in mcr-1 harboring carbapenem-resistant enterobacterales isolates from human in Thailand

Scientific Reports, 2022
The emergence of the mobile colistin-resistance genes mcr-1 has attracted significant attention worldwide. This study aimed to investigate the genetic features of mcr-1-carrying plasmid among carbapenem-resistant Enterobacterales (CRE) isolates and the ...
Parichart Boueroy, Thidathip Wongsurawat, Piroon Jenjaroenpun, Peechanika Chopjitt, Rujirat Hatrongjit, Sathaporn Jittapalapong, Anusak Kerdsin   +6 more
doaj   +1 more source