Results 71 to 80 of about 1,638 (164)
Antibiotic treatment leads to expansion of facultative anaerobic Escherichia spp. (proteobacteria) in calves, a signature of imbalanced microbiota, dysbiosis. This in turn enhances a risk of the growth of bacteria that carry highly mobile clinically relevant resistances that can be transmitted to humans. Summary In agriculture, antibiotics are used for
Dorota A. Dobrzanska +8 more
wiley +1 more source
We describe a hospital-based outbreak caused by multidrug-resistant, Klebsiella pneumoniae carbapenemase 3–producing, mcr-1–positive K. pneumoniae sequence type 45 in Portugal. mcr-1 was located in an IncX4 plasmid. Our data highlight the urgent need for
Ana Constança Mendes +7 more
doaj +1 more source
Identification and characterization of mcr mediated colistin resistance in extraintestinal Escherichia coli from poultry and livestock in China [PDF]
Antimicrobial resistance to colistin has emerged worldwide threatening the efficacy of one of the last-resort antimicrobials used for the treatment of multidrug-resistant Enterobacteriaceae infection in humans. In this study, we investigated the presence
Butaye, Patrick +15 more
core +2 more sources
Regulatory fine-tuning of mcr-1 increases bacterial fitness and stabilises antibiotic resistance in agricultural settings [PDF]
Antibiotic resistance tends to carry fitness costs, making it difficult to understand how resistance can be maintained in the absence of continual antibiotic exposure. Here we investigate this problem in the context of mcr-1, a globally disseminated gene
Jangir, Pramod +6 more
core +2 more sources
Until recently, the role of insects, and particularly flies, in disseminating antimicrobial resistance (AMR) has been poorly studied. In this study, we screened blowflies (Chrysomya spp.) from different areas near the city of Phitsanulok, Northern ...
Qiu E. Yang +11 more
doaj +1 more source
Genomic Features of MCR-1 and Extended-Spectrum β-Lactamase-Producing Enterobacterales from Retail Raw Chicken in Egypt. [PDF]
Colistin is considered as a last resort agent for treatment of severe infections caused by carbapenem-resistant Enterobacterales (CRE). Recently, plasmid-mediated colistin resistance genes (mcr type) have been reported, mainly corresponding to mcr-1 ...
Abdelfattah Maky, M. +5 more
core +1 more source
Whole genome insights into diarrhoeagenic Escherichia coli (DEC) strains from Southern Africa → Study focus: Comparative genomics of DEC strains isolated from food, clinical and environmental sources in Southern Africa. Key Findings: 1. High genetic diversity → Region‐specific distribution system observed from association trends between strains from ...
Josphat Gichure, Tina Hald, Elna Buys
wiley +1 more source
The global food chain may significantly promote the dissemination of bacteria resistant to antibiotics around the world. This study was aimed at determining the prevalence and genetic characteristics of Enterobacteriaceae with mcr-mediated colistin (CT ...
Tereza Gelbíčová +9 more
doaj +1 more source
Aquaculture systems are widely recognised as hotspots for horizontal gene transfer, and the need for screening for bacteria carrying antimicrobial resistance genes in aquaculture systems is becoming more important.
Alžběta Kalová +4 more
doaj +1 more source
Expanding landscapes of the diversified mcr-1-bearing plasmid reservoirs [PDF]
BACKGROUND: Polymyxin is a cationic polypeptide antibiotic that can disrupt bacterial cell membrane by interacting with its lipopolysaccharide molecules and is used as a last resort drug against lethal infections by the carbapenem-resistant superbugs ...
Ding, Youfa +7 more
core +2 more sources

