Results 91 to 100 of about 1,638 (164)

High rates of human fecal carriage of mcr-1-positive multi-drug resistant Enterobacteriaceae isolates emerge in China in association with successful plasmid families [PDF]

, 2017
Objectives mcr-1-mediated colistin resistance in Enterobacteriaceae is concerning, as colistin is used in treating multidrug-resistant Enterobacteriaceae infections. Rates of human mcr-1 gastrointestinal carriage have historically been low. We identified
Crook, DW, Doi, Y, Feng, LQ, Huang, X, Li, HY, Lin, J, Patil, S, Phan, HTT, Shen, C, Sheppard, AE, Stoesser, N, Tian, GB, Vihta, KD, Walker, Ann, Xia, Y, Zeng, KJ, Zhang, XF, Zhong, LL, Zing, Y   +18 more
core   +2 more sources

Prevalence and molecular epidemiology of carbapenemase‐producing Enterobacterales isolated from dog and cat faeces submitted to veterinary laboratories in the USA

Zoonoses and Public Health, Volume 71, Issue 5, Page 538-548, August 2024.
Abstract Aims To estimate the prevalence of carbapenemase‐producing Enterobacterales (CPE) carriage among pets using faecal specimens submitted to veterinary diagnostic laboratories throughout the US. A secondary aim was to employ whole‐genome sequencing (WGS) to characterize isolates of CPE from companion animals and compare them to publicly available
Jaclyn Dietrich, Tessa E. LeCuyer, G. Kenitra Hendrix, Claire R. Burbick, Megan E. Jacob, Barbara A. Byrne, Karen Olsen, Maria Mitchell, Olgica Ceric, Rachel Lin, Jessica Joneson, Megan Lintner, Alexandra Fox, Diamond McClendon, Trevor Alexander, Kayla Joyce, Melissa Byrd, Jason Clinton, Keith Snipes, Laura Peak, Stephen D. Cole   +20 more
wiley   +1 more source

Microbial evolution through horizontal gene transfer by mobile genetic elements

Microbial Biotechnology, Volume 17, Issue 1, January 2024.
This mini‐review explores the behaviour of conjugative plasmids in various environments, discusses recent methodologies for tracking mobile genetic elements (MGE) dynamics, and underscores the importance of understanding horizontal gene transfer (HGT) mechanisms to develop effective strategies against antimicrobial resistance genes (ARGs) dissemination.
Maho Tokuda, Masaki Shintani
wiley   +1 more source

First Report and Characterization of the mcr-1 Positive Multidrug-Resistant Escherichia coli Strain Isolated from Pigs in Croatia

Microorganisms, 2023
The emergence and rapid spread of the plasmid-mediated colistin-resistant mcr-1 gene introduced a serious threat to public health. In 2021, a multi-drug resistant, mcr-1 positive Escherichia coli EC1945 strain, was isolated from pig caecal content in ...
Gordan Kompes, Sanja Duvnjak, Irena Reil, Rene S. Hendriksen, Lauge Holm Sørensen, Maja Zdelar-Tuk, Boris Habrun, Luka Cvetnić, Antonela Bagarić, Silvio Špičić   +9 more
doaj   +1 more source

A Broad‐Spectrum Horizontal Transfer Inhibitor Prevents Transmission of Plasmids Carrying Multiple Antibiotic Resistance Genes

Transboundary and Emerging Diseases, Volume 2024, Issue 1, 2024.
The dissemination of antimicrobial resistance (AMR) severely degrades the performance of antibiotics and constantly paralyzes the global health system. In particular, plasmid‐mediated transfer of antibiotic resistance genes (ARGs) across bacteria is recognized as the primary driver.
Yuqian Jia, Zhiwan Zheng, Bingqing Yang, Haijie Zhang, Zhiqiang Wang, Yuan Liu, Mohsin Khurshid   +6 more
wiley   +1 more source

Klebsiella pneumoniae arms itself: poultry food chain drives spread and evolution of mcr-1.26- IncX4 plasmids

Microbiology Spectrum
No abstract available!
Binsker, Ulrike, Hammerl, Jens André, Käsbohrer, Annemarie, García-Meniño, Isidro, Salzinger, Carina, Borowiak, Maria, Jäckel, Claudia, Rau, Jörg   +7 more
openaire   +4 more sources

Key features of mcr-1-bearing plasmids from Escherichia coli isolated from humans and food

Antimicrobial Resistance and Infection Control, 2017
Background Mcr-1-harboring Enterobacteriaceae are reported worldwide since their first discovery in 2015. However, a limited number of studies are available that compared full-length plasmid sequences of human and animal origins.
Katrin Zurfluh, Magdalena Nüesch-Inderbinen, Jochen Klumpp, Laurent Poirel, Patrice Nordmann, Roger Stephan   +5 more
doaj   +1 more source

Plasmid‐Mediated Co‐Occurrence of mcr-1.1 in Extended‐Spectrum β‐Lactamase (ESBL)‐Producing Escherichia coli Isolated From the Indigenous Seminomadic Community in Malaysia

Transboundary and Emerging Diseases, Volume 2024, Issue 1, 2024.
The growing prevalence of commensal antibiotic resistant Escherichia coli poses a significant concern for the global spread of antibiotic resistance. Stool samples (n = 35) from a seminomadic indigenous community in Malaysia, the Jehai, were screened for multidrug‐resistant bacteria, specifically the extended‐spectrum β‐lactamase (ESBL) producers ...
Polly Soo Xi Yap, Li-Fang Yeo, Cindy Shuan Ju Teh, Amreeta Dhanoa, Maude Elvira Phipps, Mashkoor Mohsin   +5 more
wiley   +1 more source

Identification and Genomic Analyses of a Multidrug Resistant Avian Pathogenic Escherichia coli Coharboring mcr-1, blaTEM-176 and blaCTX-M-14 Genes

Transboundary and Emerging Diseases, Volume 2024, Issue 1, 2024.
The emergence and transmission of the colistin‐resistance gene mcr and extended‐spectrum β‐lactamase (ESBL) encoding genes pose a significant threat to global public health. In recent years, it has been reported that mcr-1 and ESBL genes can coexist in single bacteria strain.
Zhiyang Wang, Xinyu Wang, Weiqi Guo, Di Wang, Jiangang Hu, Beibei Zhang, Jingjing Qi, Mingxing Tian, Yanqing Bao, Haihua Li, Shaohui Wang, Abdelfattah Selim   +11 more
wiley   +1 more source

Remarkable Diversity of Escherichia coli Carrying mcr-1 from Hospital Sewage with the Identification of Two New mcr-1 Variants

Frontiers in Microbiology, 2017
The plasmid-borne colistin-resistant gene mcr-1 has rapidly become a worldwide public health concern. This study aims to determine the host bacterial strains, plasmids, and genetic contexts of mcr-1 in hospital sewage.
Feifei Zhao, Feifei Zhao, Yu Feng, Yu Feng, Xiaoju Lü, Xiaoju Lü, Alan McNally, Zhiyong Zong, Zhiyong Zong, Zhiyong Zong   +9 more
doaj   +1 more source