Results 101 to 110 of about 1,638 (164)

Comparative genomic analyses of Polymyxin-resistant Enterobacteriaceae strains from China

BMC Genomics, 2022
Background Mobile colistin resistance like gene (mcr-like gene) is a new type of polymyxin resistance gene that can be horizontally transferred in the Enterobacteriaceae.
Zhien He, Yongqiang Yang, Wei Li, Xiaoling Ma, Changfeng Zhang, Jingxiang Zhang, Baolin Sun, Tao Ding, Guo-bao Tian   +8 more
doaj   +1 more source

The roles of HicBA and a novel toxin–antitoxin-like system, TsxAB, in the stability of IncX4 resistance plasmids in Escherichia coli

Journal of Antimicrobial Chemotherapy, 2018
To identify toxin-antitoxin (TA)-like plasmid stability loci on IncX4 plasmids.TA-like loci were identified bioinformatically and their contribution to stability of the IncX4 plasmid pJIE143 was tested in optimal growth conditions in vitro. The conservation of the TA-like loci identified was analysed within an updated IncX plasmid database.A novel TA ...
Bustamante, Paula, Iredell, Jonathan R.
openaire   +3 more sources

Repeated Occurrence of Mobile Colistin Resistance Gene-Carrying Plasmids in Pathogenic Escherichia coli from German Pig Farms

Microorganisms
The global spread of plasmid-mediated mobile colistin resistance (mcr) genes threatens the vital role of colistin as a drug of last resort. We investigated whether the recurrent occurrence of specific E.
Lisa Göpel, Ellen Prenger-Berninghoff, Silver A. Wolf, Torsten Semmler, Rolf Bauerfeind, Christa Ewers   +5 more
doaj   +1 more source

Heterogeneous and flexible transmission of mcr-1 in hospital-associated escherichia coli [PDF]

, 2018
The recent emergence of a transferable colistin resistance mechanism, MCR-1, has gained global attention because of its threat to clinical treatment of infections caused by multidrug-resistant Gram-negative bacteria.
Cai, Jiachang, Johnson, Eric A., Lei, Lei, Li, Mei, Shen, Jianzhong, Shen, Yingbo, Shen, Zhangqi, Tian, Guo-Bao, Tyrrell, Jonathan, Walsh, Timothy R., Wang, Shaolin, Wang, Yang, Wu, Congming, Wu, Zuowei, Zhang, Qijing, Zhang, Rong, Zhou, Hong-Wei   +16 more
core   +4 more sources

Colistin Resistance Mediated by mcr-1 in ESBL-Producing, Multidrug Resistant Salmonella Infantis in Broiler Chicken Industry, Italy (2016–2017)

Frontiers in Microbiology, 2018
Colistin-resistance mediated by mobilisable and plasmid-borne mcr genes has emerged worldwide, threatening the efficacy of colistin, a last resort antibiotic increasingly used for treating human invasive infections by multidrug-resistant or extensively ...
Virginia Carfora, Patricia Alba, Pimlapas Leekitcharoenphon, Daniele Ballarò, Gessica Cordaro, Paola Di Matteo, Valentina Donati, Angela Ianzano, Manuela Iurescia, Fiorentino Stravino, Tania Tagliaferri, Antonio Battisti, Alessia Franco   +12 more
doaj   +1 more source

New insights on mcr-1-harboring plasmids from human clinical Escherichia coli isolates.

PLoS ONE
Mobile colistin resistance (mcr) genes were described recently in Gram-negative bacteria including carbapenem-resistant Enterobacterales. There are ten mcr genes described in different Gram-negative bacteria, however, Escherichia coli harboring mcr-1 ...
Florencia Martino, Alejandro Petroni, María Alejandra Menocal, Alejandra Corso, Roberto Melano, Diego Faccone   +5 more
doaj   +1 more source

First three Escherichia coli isolates harbouring mcr-1 in Uruguay [PDF]

, 2020
Objective: This report described the first Escherichia coli (E. coli) isolates harbouring mcr-1 in Uruguay. Methods: Three E. coli isolates were obtained from blood, urine and rectal swabs from different patients in two hospitals.
Algorta, Gabriela, Brasesco, María, Caiata, Leticia, Christophersen, Inés, Cordeiro, Nicolás F., Galiana, Antonio, García-Fulgueiras, Virginia, Grill Diaz, Fabio, Papa-Ezdra, Romina, Vieytes, Mariela, Vignoli, Rafael, Ávila, Pablo   +11 more
core   +1 more source

The global distribution and spread of the mobilized colistin resistance gene mcr-1. [PDF]

, 2018
Colistin represents one of the few available drugs for treating infections caused by carbapenem-resistant Enterobacteriaceae. As such, the recent plasmid-mediated spread of the colistin resistance gene mcr-1 poses a significant public health threat ...
Balloux, Francois, Bradley, Phelim, Didelot, Xavier, Dorai-Schneiders, Thamarai, Iqbal, Zamin, Jin, Longyang, Liu, Yuqing, Rieux, Adrien, Shaw, Liam P, van Dorp, Lucy, Wang, Hui, Wang, Qi, Wang, Ruobing, Wang, Xiaojuan, Weinert, Lucy Anne, Zhang, Qing   +15 more
core   +6 more sources

Retracted: In vivo mecillinam resistance in Escherichia coli after pivmecillinam treatment of a urinary tract infection

MicrobiologyOpen, Volume 8, Issue 7, July 2019., 2019
Abstract Retraction: Nielsen, KL, Hansen, KH, Knudsen, JD, Frimodt‐Møller, N, Hertz, FB, Jansåker, F., In vivo mecillinam resistance in Escherichia coli after pivmecillinam treatment of a urinary tract infection, MicrobiologyOpen, 2019; e770 (https://doi.org/10.1002/mbo3.770).
wiley   +1 more source

Genetic Characterization of Colistin-Resistant Salmonella enterica ST34 Co-Harbouring Plasmid-Borne mcr-1, blaCTX-M-15 and blaKPC-2 Recovered from a Paediatric Patient in Shenzhen, China

Infection and Drug Resistance, 2022
Sandip Patil,1,2 Xiaorong Liu,2 Hongyu Chen,3 Ngiambudulu M Francisco,4 Feiqiu Wen,1,2 Yixin Chen5,6 1Department of Haematology and Oncology, Shenzhen Children’s Hospital, Shenzhen, Guangdong, 518038, People’s Republic of China; 2Paediatric Research ...
Patil S, Liu X, Chen H, Francisco NM, Wen F, Chen Y   +5 more
doaj