Results 11 to 20 of about 5,024 (202)

N-Difluoromethylindazoles

Журнал органічної та фармацевтичної хімії, 2022
Aim. To study the possibility of the N-difluoromethylation and separation of 1-difluoromethyl and 2-difluoromethyl isomers of C-substituted indazoles, as well as some possibilities of functionalization of such molecules. Results and discussion.
Kirill I. Petko, Andrey A. Filatov
doaj   +1 more source

Recent Strategies in Transition-Metal-Catalyzed Sequential C–H Activation/Annulation for One-Step Construction of Functionalized Indazole Derivatives

Molecules, 2022
Designing new synthetic strategies for indazoles is a prominent topic in contemporary research. The transition-metal-catalyzed C–H activation/annulation sequence has arisen as a favorable tool to construct functionalized indazole derivatives with ...
Pezhman Shiri, Atefeh Roosta, Wim Dehaen, Ali Mohammad Amani   +3 more
doaj   +1 more source

Regioselective zincation of indazoles using TMP2Zn and Negishi cross-coupling with aryl and heteroaryl iodides. [PDF]

, 2012
The metalation of various SEM-protected functionalized indazoles with TMP2Zn provides 3-zincated indazoles which undergo palladium-catalyzed Negishi cross-couplings in good ...
Andreas Unsinn, Batt, Bunnell, Bunnell, Chevallier, Clutterbuck, Collot, Crestey, Despotopoulou, Dong, Dunst, Farina, Fraile, Haag, Haag, Kienle, Knochel, Luo, Malamas, Mulvey, Negishi, Negishi, Negishi, Negishi, Negishi, Ohnmacht, Pabba, Paul Knochel, Perez, Peruncheralathan, Piazza, Pyne, Schmidt, Stadlbauer, Sun, Villieras, Welch, Whisler, Wunderlich, Wunderlich, Yang   +40 more
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“On Water” Palladium Catalyzed Direct Arylation of 1H-Indazole and 1H-7-Azaindazole

Molecules, 2020
The C3 direct arylation of 1H-indazole and 1H-7-azaindazole has been a significant challenge due to the lack of the reactivity at this position. In this paper, we describe a mild and an efficient synthesis of new series of C3-aryled 1H-indazoles and C3 ...
Khadija Gambouz, Abdelmoula El Abbouchi, Sarah Nassiri, Franck Suzenet, Mostapha Bousmina, Mohamed Akssira, Gérald Guillaumet, Saïd El Kazzouli   +7 more
doaj   +1 more source

Davis-Beirut reaction: route to thiazolo-, thiazino-, and thiazepino-2H-indazoles. [PDF]

, 2014
Methods for the construction of thiazolo-, thiazino-, and thiazepino-2H-indazoles from o-nitrobenzaldehydes or o-nitrobenzyl bromides and S-trityl-protected 1°-aminothioalkanes are reported.
Farber, Kelli M, Haddadin, Makhluf J, Kurth, Mark J   +2 more
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Хлорфенолы в органическом синтезе [PDF]

, 2016
Received: 17.08.2016; accepted: 11.10.2016; published: 01.12.2016.Поступило: 17.08.2016; приянято: 11.10.2016; опубликовано: 01.12.2016.This article reviews the alternatives for modifications of p-chlorophenols, p-chloroanisoles with the formation of C-C,
Ivanova, E. A., Mitin, V. V., Morzherin, Yu. Yu., Prokhorova, P. E., Иванова, Е. А., Митин, В. В., Моржерин, Ю. Ю., Прохорова, П. Е.   +7 more
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Chalcones as versatile synthons for the synthesis of 5- and 6-membered nitrogen heterocylces [PDF]

, 2014
Chalcones belong to the flavonoid family which constitutes one of the major classes of naturally occurring oxygen heterocyclic compounds. The alpha,beta-unsaturated carbonyl system of chalcones possesses two electrophilic reactive centers allowing them ...
Albuquerque, Hélio, Cavaleiro, José, Santos, Clementina M.M., Silva, Artur   +3 more
core   +1 more source

Visible light-promoted transition metal-free direct C3-carbamoylation of 2H-Indazoles

Frontiers in Chemistry, 2022
We reported a general transition metal-free transformation to access C3-carbamoylated 2H-indazoles via visible light-induced oxidative decarboxylation coupling, in the presence of oxamic acids as the coupling sources, 4CzIPN as the photocatalyst, and ...
Chunhua Ma, Linchun Shang, Hanying Zhao, Xing He, Qiyan Lv, Qiyan Lv, Dandan Zhang, Yuqin Jiang   +7 more
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Rhodium(I) indazole and indazolate complexes

Journal of Organometallic Chemistry, 1982
The preparation of cationic indazole (HIdz) rhodium(I) complexes of the types [(diolefin)Rh(HIdz)2]ClO4 and [(CO)2Rh(HIdz)2]ClO4 is described. Neutral binuclear rhodium(I) complexes of the type [Y2Rh(μ-Idz)]2 (Y2 = COD, TFB, NBD, (CO)2 or (CO)(PPh3)) are obtained by treating the corresponding complexes [Y2RhCl]2 with indazole and organic or inorganic ...
Usón, Rafael, Oro, Luis A., Ciriano, Miguel A., Bello, M. C.   +3 more
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Revisiting the structure and chemistry of 3(5)-Substituted Pyrazoles [PDF]

, 2019
Pyrazoles are known as versatile scaffolds in organic synthesis and medicinal chemistry, often used as starting materials for the preparation of more complex heterocyclic systems with relevance in the pharmaceutical field.
Alam, Alina Secrieru, Alkorta, Andes, Anwar, Behr, Brown, Castillo, Catalan, Chauhan, Clark, Elguero, Elnagdi, Favre, Fichez, Hall, Horta, Katritzky, Katritzky, Kost, Kumar, Larina, Maria Lurdes Santos Cristiano, Mert, Minkin, Minkin, Mohamed, Nagy, Nimbalkar, Paul Michael O’Neill, Schofield, Simons, Szajda, Taylor, Zerbi   +34 more
core   +2 more sources