Results 131 to 140 of about 49,383 (204)

Additional file 1 of Indole-3-propionic acid promotes hepatic stellate cells inactivation

Additional file 1.
Ilha, Mariana, Sehgal, Ratika, Matilainen, Johanna, Rilla, Kirsi, Kaminska, Dorota, Gandhi, Shrey, Männistö, Ville, Ling, Charlotte, Romeo, Stefano, Pajukanta, Päivi, Pirinen, Eija, Virtanen, Kirsi A., Pietiläinen, Kirsi H., Vaittinen, Maija, Pihlajamäki, Jussi   +14 more
openaire   +1 more source

A fehérje triptofán enantiomereinek meghatározása = Determination of the tryptophan enantiomers of the protein [PDF]

, 2009
A kutatás során megvalósítottuk a Trp-enantiomerek elválasztását a fehérjékben előforduló egyéb aminosavaktól 1-tio-béta-D-glükóz-tetraacetáttal és o-ftálaldehiddel képzett diasztereoizomerek formájában.
Csapó, János, Csapóné dr. Kiss, Zsuzsanna, Lóki, Katalin, Pohn, Gabriella, Vargáné Visi, Éva   +4 more
core  

Intermittent fasting promotes axonal regeneration through the gut microbiome derived metabolite: Indole-3-Propionic acid

, 2020
Spontaneous functional mammalian axonal regeneration following injury fails. High density and fast axon regeneration across distances are needed for efficient repair in humans. These are likely influenced by complex neuronal intrinsic and extrinsic metabolic and signalling mechanisms.
openaire   +3 more sources

Intestinal Homeostasis: The role of Indole-3-propionic acid (IPA) in mucosal homeostasis and repair

, 2020
Failure to resolve inflammation is often associated with the complications of Crohn’s Disease (CD). The pregnane X receptor (PXR), a xenobiotic receptor, is recognized for its role in suppressing inflammation and has recently been shown to influence fibrogenesis in the liver. In the intestine, PXR-signaling can be influenced by the microbial tryptophan
openaire   +2 more sources

Roux‐en‐Y gastric bypass surgery decreases intestinal aryl hydrocarbon receptor signaling in male mice

Physiological Reports
The impact of Roux‐en‐Y gastric bypass (RYGB) on indole metabolism and AhR signaling is poorly understood. Therefore, we tested the hypothesis that RYGB changes the indole metabolite profile in the gut, leading to changes in AhR signaling.
Annie Wang, Madelynn E. Agabao‐Tucker, Michael L. Goodson, Allison K. Ehrlich, Bethany P. Cummings   +4 more
doaj   +1 more source

Microbiota-derived IPA mitigates post-stroke neuroinflammation by inhibiting TREM2-dependent pyroptosis

Journal of Neuroinflammation
Ischemic stroke remains the leading cause of long-term disability globally, underscoring the urgent need for novel therapeutic strategies. Here, we explore a microbiota-gut-brain axis that provides valuable insights for achieving this objective ...
Jun-Min Chen, Cong Zhang, Lu-Lu Yu, Jian-Xu Sun, Jiang-Hao Zhang, Lu Chen, Fei Zhu, Guang Shi, Lan Yang, An-Chen Guo, Jian-Ping Wu, Tie-Shan Tang, Qun Wang   +12 more
doaj   +1 more source

Synthesis of 2-aminopropyl-3-indole–acetic(propionic) acid derivatives

ARKIVOC, 2003
Sophie-Isabelle Bascop, Jean-Yves Laronze, Janos Sapi   +2 more
doaj   +1 more source

Microbiota-derived indoles alleviate intestinal inflammation and modulate microbiome by microbial cross-feeding

Microbiome
Background The host–microbiota interaction plays a crucial role in maintaining homeostasis and disease susceptibility, and microbial tryptophan metabolites are potent modulators of host physiology.
Gang Wang, Yuxin Fan, Guolong Zhang, Shuang Cai, Yonghang Ma, Lijie Yang, Yuming Wang, Haitao Yu, Shiyan Qiao, Xiangfang Zeng   +9 more
doaj   +1 more source

Hydrogen-deuterium exchange of indole-3-propionic acid with deuterated trifluoromethanesulfonic acid

Hydrogen-deuterium exchange of indole-3-propionic acid with deuterated trifluoromethanesulfonic acid
Indole-3-propionic acid (IPA), a member of the plant auxin family, plays an important role in biological activity. There are few reports on the preparation of deuterated IPA. Deuterated trifluoromethanesulfonic acid (TfOD) is a hydrogen-deuterium exchange reagent used for aromatic compounds.
openaire  

Improved synthesis and comparative analysis of the tool properties of new and existing D-ring modified (S)-blebbistatin analogs [PDF]

, 2017
Bracke, Marc, Roman, Bart, Stevens, Christian, Verhasselt, Sigrid   +3 more
core   +2 more sources