From sequence-defined macromolecules to macromolecular pin codes [PDF]
, 2020 Dynamic sequence-defined oligomers carrying a chemically written pin code are obtained through a strategy combining multicomponent reactions with the thermoreversible addition of 1,2,4-triazoline-3,5-diones (TADs) to indole substrates.
Badi, Nezha +4 more
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Molecules, 2022 A new synthetic alternative to the synthesis of 3-methyl indoles and 3-methyl indoline-2-ols with an excellent atomic economy is presented in this study.
Frank Hochberger-Roa +6 more
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Indole diterpenoid natural products as the inspiration for new synthetic methods and strategies. [PDF]
, 2017 Indole terpenoids comprise a large class of natural products with diverse structural topologies and a broad range of biological activities. Accordingly, indole terpenoids have and continue to serve as attractive targets for chemical synthesis.
Corsello, Michael A +2 more
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Molecules, 2022 The current study was conducted to obtain hybrid analogues of indole-based thiadiazole derivatives (1–16) in which a number of reaction steps were involved. To examine their biological activity in the presence of the reference drug Donepezil (0.21 ± 0.12
Shoaib Khan +12 more
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Synthesis of Potential Antiviral Agents for SARS-CoV-2 Using Molecular Hybridization Approach
Molecules, 2022 We synthesized a set of small molecules using a molecular hybridization approach with good yields. The antiviral properties of the synthesized conjugates against the SAR-CoV-2 virus were investigated and their cytotoxicity was also determined.
Kailey A. Wyman +12 more
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Influence of blood meal on the responsiveness of olfactory receptor neurons in antennal sensilla trichodea of the yellow fever mosquito, Aedes aegypti [PDF]
, 2010 In female Aedes aegypti L. mosquitoes, a blood meal induces physiological and behavioral changes. Previous studies have shown that olfactory receptor neurons (ORNs) housed in grooved peg sensilla on the antennae of Ae.
Hansson, Bill +3 more
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Relationship between Aldose reductase and superoxide dismutase inhibition capacities of indole-based analogs of melatonin derivatives [PDF]
Archives of Biological Sciences, 2009 Aldose reductase (AR) has been implicated in the etiology of diabetic complications. Under diabetic conditions, the elevated vascular glucose level causes an increased flux through the polyol pathway, which induces functional and morphological changes ...
Daş-Evcimen N., Yildirim Ö., Suzen S.
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Biologically active compounds from selected aphyllophorales mycelial cultures [PDF]
, 2014 The obtained results confirm the hypothesis that mycelial cultures of domestic species of aphyllophorales are able to accumulate biologically active metabolites.Uzyskane wyniki wskazują, że przebadane kultury mycelialne krajowych gatunków grzybów ...
Firlej, Anna +2 more
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Feeding with chicory roots reduces the amount of odorous compounds in colon and rectal contents of pigs [PDF]
, 2006 Sixteen pigs (eight entire males and eight females) were given individually two diets, control and control added 25% chopped chicory roots for 2 months before slaughter.
Hansen, L.L., Jensen, M.T.
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Proton transfer in histidine-tryptophan heterodimers embedded in helium droplets
, 2015 We used cold helium droplets as nano-scale reactors to form and ionize, by electron bombardment and charge transfer, aromatic amino acid heterodimers of histidine with tryptophan, methyl-tryptophan, and indole. The molecular interaction occurring through
Bellina, Bruno +2 more
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