Results 111 to 120 of about 30,006 (268)
Evaluation of Biosynthetic Pathway and Engineered Biosynthesis of Alkaloids
Molecules, 2016 Varieties of alkaloids are known to be produced by various organisms, including bacteria, fungi and plants, as secondary metabolites that exhibit useful bioactivities.
Shinji Kishimoto +3 more
doaj +1 more source
Chemical Studies of Indole Alkaloids
YAKUGAKU ZASSHI, 1995 Up to now, more than two thousands indole alkaloids having structural variety have been found from the three families of Gentianales: Loganiaceae, Apocynaceae, and Rubiaceae plants. These compounds generally possess characteristic biological activities and many of them are utilized for the medicinal purpose and for the lead-compounds to develop new ...
openaire +3 more sources
Oxygen Attachment Dissociation of Protonated Reserpine and Its Analogs
Rapid Communications in Mass Spectrometry, Volume 40, Issue 14, 30 July 2026.ABSTRACT Rationale Carbon–carbon double bonds are ubiquitous structural motifs in natural products and pose a key challenge in locating their presence in analytes via MS‐based methods. Here, we use the alkaloid reserpine as a model system to examine whether OAD reactions can locate quaternary double bonds embedded in fused multicyclic structures ...
Jack G. Li +5 more
wiley +1 more source
Advanced Synthesis &Catalysis, Volume 368, Issue 9, 5 May 2026.Heterogeneous‐catalyzed selective and versatile hydrogenative functionalizations of phthalimides have been developed for the first time. By using a solid nanocomposite formed by [Ag/Al2O3] material in combination with [H‐BETA] zeolite as cocatalyst, a broad range of 3‐functionalized isoindolinones have been accesed in one‐pot from phthalimides, H2 and ...
Carles Lluna‐Galán +2 more
wiley +1 more source
Advanced Synthesis &Catalysis, Volume 368, Issue 9, 5 May 2026.The enantioselective synthesis of naphthocoumarin adducts via a tandem organocatalytic 1,4‐addition/decarboxylation delivers excellent control over a newly forged stereocenter and yields configurationally stable synclinal atropisomers. The process features broad substrate scope and scalability, and its structural and mechanistic foundations are ...
M. Chiara Cabua +10 more
wiley +1 more source
Angewandte Chemie, Volume 138, Issue 17, 20 April 2026.The thiocarbenium ion rearrangement of 3‐dihydrodisorhabdin B greatly increases the recovery of aleutianamine from Latrunculia spp., a pyrroloiminoquinone natural product with potent activity against drug‐resistant cancers, collected from the deep‐ocean along the Aleutian Islands.
Cody F. Dickinson +13 more
wiley +2 more sources
Food Frontiers, Volume 7, Issue 3, May 2026.Natural compounds regulate gut microbiota by improving microbial balance and increasing probiotics, which boost short‐chain fatty acid production to alleviate insulin resistance and inflammation. Additionally, they stimulate appetite‐suppressing hormones through bile acid signaling, while inhibiting pathogenic bacteria to repair intestinal barrier ...
Hongchao Yuan +7 more
wiley +1 more source
Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.ABSTRACT Ergot alkaloids (EAs), toxic secondary metabolites produced by Claviceps purpurea, pose food and feed safety concerns for cereal grains, particularly rye and wheat. While EAs are most frequently associated with rye, their occurrence in other cereals has been increasingly reported across diverse regions.
Chamali Kodikara +2 more
wiley +1 more source
Plant Biotechnology Journal, Volume 24, Issue 5, Page 2876-2890, May 2026.ABSTRACT The synthesis and accumulation of active ingredients in medicinal plants are distributed in specific organs, tissues, and cell types, which are important for the exploitation of medicinal plants. However, the fine distribution of active ingredients is difficult to know. Here, the system of mass spectrometry imaging (MSI) integrated with single‐
HaiSheng Zeng +14 more
wiley +1 more source
Angewandte Chemie, Volume 138, Issue 15, 6 April 2026.A gram‐scale supply of bulbiferamide A, which features a rare N‐acylindole linkage and possesses potent inhibitory activity against Trypanosoma cruzi epimastigotes (IC50 = 4.1 µM)—the causative parasite of Chagas disease—was successfully achieved. Moreover, the cyclization strategy developed in this study facilitated the synthesis of noncanonical ...
Jie Zhang, Hugh Nakamura
wiley +2 more sources