Omics analyses of Rehmannia glutinosa dedifferentiated and cambial meristematic cells reveal mechanisms of catalpol and indole alkaloid biosynthesis. [PDF]
Zhou P +11 more
europepmc +1 more source
The biosynthesis of monoterpenoid indole alkaloids from strictosidine [PDF]
Nagakura, Naotaka +2 more
core +1 more source
This review summarizes microwave‐assisted transition‐metal catalysis for constructing N‐ and O‐heterocycles, highlighting rapid C–H and pre‐activated C–X activation, improved selectivity, and green synthetic efficiency. Abstract Microwave‐assisted organic synthesis provides a rapid and sustainable platform for synthesizing various heterocycles ...
Woo‐Jin Park, Ye Ri Han, Hyejeong Lee
wiley +1 more source
Unveiling an indole alkaloid diketopiperazine biosynthetic pathway that features a unique stereoisomerase and multifunctional methyltransferase. [PDF]
Deletti G +10 more
europepmc +1 more source
ABSTRACT This study aimed to evaluate the antitumor activity of fractions rich in indole alkaloids extracted from the leaves of the species Tabernaemontana catharinensis. The chemical composition was analyzed using high‐resolution mass spectrometry (HRMS), which identified nine known indole alkaloids, including voacangine, voacangine hydroxyindolenine,
Ana Júlia Gomes Donada +5 more
wiley +1 more source
A New Hypoglycemic Prenylated Indole Alkaloid N-Oxide from Endophytic Fungus Pallidocercospora crystalline. [PDF]
Gao S +6 more
europepmc +1 more source
We report a biosynthesis‐inspired ring distortion approach that involves oxidative ring cleavage, ring rearrangement, and ring expansion reactions from a diverse collection of indole alkaloids and derivatives. This chemical synthesis approach led to the synthesis of >25 distinct chemotypes from 14 indole alkaloids.
Derek A. Leas +7 more
wiley +1 more source
The Vinca minor genome highlights conserved evolutionary traits in monoterpene indole alkaloid synthesis. [PDF]
Stander EA +15 more
europepmc +1 more source
Wherefore the Magic? The Evolutionary Role of Psilocybin in Nature
This study explores the evolutionary role of psilocybin, the psychedelic compound found in Psilocybe mushrooms. We provide the first experimental tests of defence and community‐level evidence for invertebrate responses to psilocybin‐producing fungi, revealing significant negative effects on invertebrate locomotion, development, and survival.
K. J. Matthews Nicholass +16 more
wiley +1 more source
Deciphering and reprogramming the cyclization regioselectivity in bifurcation of indole alkaloid biosynthesis. [PDF]
Wang Z +5 more
europepmc +1 more source

