Results 11 to 20 of about 19,941 (251)
Modular assembly of indole alkaloids enabled by multicomponent reaction
Nature Communications, 2023 Indole alkaloids are one of the largest alkaloid classes, proving valuable structural moiety in pharmaceuticals. Although methods for the synthesis of indole alkaloids are constantly explored, the direct single-step synthesis of these chemical entities ...
Jiaming Li +4 more
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Natural Product-Oriented Photo-Induced Denitrogenative Annulations of 1-Alkenylbenzotriazoles
Molecules, 2023 The photo-induced denitrogenative annulations of a variety of 1-alkenylbenzotriazoles were investigated. By judiciously manipulating the structural variations of 1-alkenylbenzotriazoles, two characteristic polycyclic skeletons associated with monoterpene
Zhiguo Wang +3 more
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Plants, 2021 Cell and tissue cultures of Catharanthus roseus have been studied extensively as an alternative strategy to improve the production of valuable secondary metabolites. The purpose of this study was to produce C. roseus callus and suspension cell biomass of
Tran My Linh +6 more
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Indole-Based Tubulin Inhibitors: Binding Modes and SARs Investigations
Molecules, 2022 Tubulin inhibitors can interfere with normal cell mitosis and inhibit cell proliferation through interfering with the normal structure and function of microtubules, forming spindle filaments.
Sheng Tang +4 more
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Fungal indole alkaloid biogenesis through evolution of a bifunctional reductase/Diels–Alderase [PDF]
Nature Chemistry, 2019 Qingyun Dan +2 more
exaly +2 more sources
Binary Stress Induces an Increase in Indole Alkaloid Biosynthesis in Catharanthus roseus
Frontiers in Plant Science, 2015 Catharanthus roseus is an important medicinal plant, which produces a variety of indole alkaloids of significant pharmaceutical relevance. In the present study, we aimed to investigate the potential stress-induced increase of indole alkaloid biosynthesis
Wei eZhu +5 more
doaj +1 more source
A New Erythrinan Alkaloid Glycoside from the Seeds of Erythrina crista-galli
Molecules, 2017 A new Erythrina alkaloid glycoside, named erythraline-11β-O-glucopyranoside, was isolated from the seeds of Erythrina crista-galli L., together with five known Erythrina alkaloids and an indole alkaloid.
Qing-Wei Tan +3 more
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Chemical and Biological Technologies in Agriculture, 2023 Background Tobacco mosaic virus (TMV) is a harmful plant pathogen that causes a decline in the quality and yield of many economic crops. Natural products are important potential sources of biopesticides for the prevention and treatment of TMV. This study
Hua-Yin Liu +8 more
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AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Toxins, 2015 The grass parasitic fungus Claviceps purpurea sensu lato produces sclerotia with toxic indole alkaloids. It constitutes several genetic groups with divergent habitat preferences that recently were delimited into separate proposed species.
Mariell Negård +5 more
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