Results 201 to 210 of about 31,469 (239)
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Cytotoxicity of Modified Indole Alkaloids
Journal of Pharmaceutical Sciences, 1979Indole alkaloids of the iboga series were structurally modified by incorporation of a 3,4-dimethoxybenzyl or -benzoyl unit so that they contained the N-O-O triangle required for antileukemic activity according to the triangulation hypothesis. The cytotoxicities of the modified alkaloids in the in vitro P-388 system were not significantly increased over
D G, Kingston, S M, Sami
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Indole alkaloids from Gelsemium elegans
Phytochemistry, 2019Five previously undescribed monoterpenoid indole alkaloids were isolated from the roots of Gelsemium elegans. Their structures with absolute configurations were elucidated by HRESIMS, X-ray diffraction, ECD spectra, and molecular modeling. 19,20-Epoxyhumantenine is a humantenine-type alkaloid with an epoxypropyl group at the C-20 position, (4R)-19-oxo ...
Ming-Xue, Sun +7 more
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Indole alkaloids from Ervatamia chinensis
Phytochemistry, 2012Four vobasinyl-ibogan type bisindole alkaloids, ervachinines A-D (1-4), along with 12 known terpenoid indole alkaloids, were isolated from the whole plant of Ervatamia chinensis. Their structures were elucidated by analysis of spectroscopic data, including 1D and 2D NMR, and the absolute configurations of 1-4 were determined by CD exciton chirality ...
Ling-Li, Guo +9 more
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Indole Prenylation in Alkaloid Synthesis
2011Important biologically active indole alkaloids are decorated with prenyl (3,3-dimethylallyl) and tert-prenyl (1,1-dimethylallyl) groups. Covering the literature until the end of 2010, this review article comprehensively summarises and discusses the currently available technologies of prenylation and tert-prenylation of indoles, which have been applied ...
Thomas, Lindel +2 more
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1991
Publisher Summary This chapter focuses on new indole-containing natural products and their biological activity. A tremendous increase in the number of indole natural products has occurred in the areas of plant alkaloids, fungal metabolites, and marine natural products.
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Publisher Summary This chapter focuses on new indole-containing natural products and their biological activity. A tremendous increase in the number of indole natural products has occurred in the areas of plant alkaloids, fungal metabolites, and marine natural products.
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Indole Alkaloids In Plant Hallucinogens
Journal of Psychedelic Drugs, 1976(1976). Indole Alkaloids In Plant Hallucinogens. Journal of Psychedelic Drugs: Vol. 8, No. 1, pp. 7-25.
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