Results 11 to 20 of about 1,668,623 (259)
Indole derivatives with therapeutic properties [PDF]
Farmacja Polska, 2021 The bicyclic ring system of indole (benzo[b]pyrrole) is a structural element of many therapeutic agents used in medical practice with diverse biological activities, including anticancer, antibacterial, antiviral, anti-inflammatory, analgesic, antipyretic
Anita Kornicka +3 more
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Indole-Based Tubulin Inhibitors: Binding Modes and SARs Investigations
Molecules, 2022 Tubulin inhibitors can interfere with normal cell mitosis and inhibit cell proliferation through interfering with the normal structure and function of microtubules, forming spindle filaments.
Sheng Tang +4 more
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Acta Pharmaceutica Sinica B, 2022 Cancer, which is the uncontrolled growth of cells, is the second leading cause of death after heart disease. Targeting drugs, especially to specific genes and proteins involved in growth and survival of cancer cells, is the prime need of research world ...
Ashima Dhiman, Rupam Sharma, R. Singh
semanticscholar +1 more source
Antibiofilm and Antivirulence Properties of Indoles Against Serratia marcescens
Frontiers in Microbiology, 2020 Indole and its derivatives have been shown to interfere with the quorum sensing (QS) systems of a wide range of bacterial pathogens. While indole has been previously shown to inhibit QS in Serratia marcescens, the effects of various indole derivatives on
Sivasamy Sethupathy +4 more
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Synthesis of indole derivatives as prevalent moieties present in selected alkaloids
RSC Advances, 2021 Indoles are a significant heterocyclic system in natural products and drugs. They are important types of molecules and natural products and play a main role in cell biology.
M. Heravi +3 more
semanticscholar +1 more source
Journal of Basic and Applied Research in Biomedicine, 2022 Indole, the bicyclic ring system consists of pyrrole ring fused with benzene ring. Although indole moiety is very small but is fascinated by scientists because of the diverse biological activities by not only indole but its various substituted ...
Kondeti Naveen +4 more
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Fe3O4 magnetic nanoparticles (MNPs) as an effective catalyst for synthesis of indole derivatives [PDF]
Nanochemistry Research, 2018 The principal aim of this research is the application of Fe3O4 (MNPs) in the synthesis of some indole derivatives. Fe3O4 MNPs were prepared by Co-Precipitation method from the reaction of FeCl2.4H2O and FeCl3.6H2O in ammonia solution.
Zohreh Rostami +3 more
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Molbank, 2021 Based on recent discoveries concerning the numerous biological properties of thiazolidinones and thiosemicarbazones, new N-substituted heterocyclic derivatives have been designed by combining the indole ring with thioxothiazolidinone, thiazolidinone or ...
Nawel Rekiba +4 more
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Synthesis of biologically active sulfonamide-based indole analogs: a review
Future Journal of Pharmaceutical Sciences, 2023 The class of heterocyclic compounds exhibits a variety of pharmacological actions, long employed as an active ingredient in drug design and production. Indole and its derivatives are crucial in medicinal chemistry. Due to its physiological action, it has
Irfan Mushtaq, Adnan Ahmed
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Frontiers in Molecular Biosciences, 2021 This work investigated the interaction of indole with SARS-CoV-2. Indole is widely used as a medical material owing to its astounding biological activities.
Perumal Gobinath +7 more
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