Results 11 to 20 of about 2,631 (199)

Clostridium difficile Modulates the Gut Microbiota by Inducing the Production of Indole, an Interkingdom Signaling and Antimicrobial Molecule

open access: yesmSystems, 2019
Clostridium (Clostridioides) difficile infection (CDI) is associated with dysbiosis. C. difficile has a characteristic propensity to persist and recur 1 to 4 weeks after treatment, but the mechanism is unknown. We hypothesized that C.
Charles Darkoh   +3 more
doaj   +1 more source

Indole production capacity in three different Escherichia coli strains [PDF]

open access: yesJournal of Advanced Pharmacy Research
Background: In Escherichia coli, the enzyme tryptophanase (TnaA) is responsible for the production of indole from tryptophan. However, the factors governing the production and excretion levels of indole by Escherichia coliremain uncertain, complicating ...
Galila Salama   +3 more
doaj   +1 more source

Indol production by bacteria [PDF]

open access: yesInternational Journal of Systematic Bacteriology, 1966
ABSTRACT Production of indol by bacteria appears to be limited to those which produce acid from glucose fermentatively and reduce nitrate. From more limited experience, Gram - positive and pigmented bacteria did not produce indol.
openaire   +1 more source

Regulation of Indole Signalling during the Transition of E. coli from Exponential to Stationary Phase.

open access: yesPLoS ONE, 2015
During the transition from exponential to stationary phase E. coli produces a substantial quantity of the small, aromatic signalling molecule indole. In LB medium the supernatant indole concentration reaches a maximum of 0.5-1 mM.
Hannah Gaimster, David Summers
doaj   +1 more source

Characterization of indole-3-pyruvic acid pathway-mediated biosynthesis of auxin in Neurospora crassa. [PDF]

open access: yesPLoS ONE, 2018
Plants, bacteria and some fungi are known to produce indole-3-acetic acid (IAA) by employing various pathways. Among these pathways, the indole-3-pyruvic acid (IPA) pathway is the best studied in green plants and plant-associated beneficial microbes ...
Puspendu Sardar, Frank Kempken
doaj   +1 more source

Production of indole pigments byCandida glabrata [PDF]

open access: yesMedical Mycology, 2007
When provided as the sole nitrogen source tryptophan induces the production of several indole alkaloids, e.g., pityriacitrin, malasseziaindole, pityriaanhydride and pityriarubin with proven biological activity in the lipophilic yeast Malassezia furfur. So far these pigments seem to have been unique and only produced by highly specialized basidiomycetal
Mayser, Peter   +5 more
openaire   +3 more sources

Bacterial Indole as a Multifunctional Regulator of Klebsiella oxytoca Complex Enterotoxicity

open access: yesmBio, 2022
Gastrointestinal microbes respond to biochemical metabolites that coordinate their behaviors. Here, we demonstrate that bacterial indole functions as a multifactorial mitigator of Klebsiella grimontii and Klebsiella oxytoca pathogenicity.
Nagender Ledala   +20 more
doaj   +1 more source

Effect of Bromination on the Quorum Sensing-Inhibiting Properties of Indole-3-Carboxaldehydes in Chromobacterium violaceum AHL System

open access: yesMicrobiology Research, 2021
Quorum sensing (QS) is a form of bacterial communication involved in the production of virulence factors in many species. As a result, inhibition of quorum sensing may be of use in mitigating pathogenesis. The signaling molecule indole is currently being
Chesley A. Kemp   +3 more
doaj   +1 more source

Targeting the gut microbial metabolic pathway with small molecules decreases uremic toxin production

open access: yesGut Microbes, 2020
Uremic toxins are a class of toxins that accumulate in patients with chronic kidney disease (CKD). Indoxyl sulfate (IS), a typical uremic toxin, is not efficiently removed by hemodialysis.
Yingyi Wang   +10 more
doaj   +1 more source

Indole ring oxidation by activated leukocytes prevents the production of hypochlorous acid

open access: yesBrazilian Journal of Medical and Biological Research, 2005
Hypochlorous acid (HOCl) released by activated leukocytes has been implicated in the tissue damage that characterizes chronic inflammatory diseases. In this investigation, 14 indole derivatives, including metabolites such as melatonin, tryptophan and ...
V.F. Ximenes   +4 more
doaj   +1 more source

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