Results 11 to 20 of about 82,415 (199)
Indole Inhibits IncP-1 Conjugation System Mainly Through Promoting korA and korB Expression
Frontiers in Microbiology, 2021 Indole works as an interspecies signal molecule to regulate multiple physiological activities, like antibiotic resistance, acid resistance, and virulence. However, the effect of indole on conjugation is unknown.
Rui Xiong +8 more
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Antibiofilm and Antivirulence Properties of Indoles Against Serratia marcescens
Frontiers in Microbiology, 2020 Indole and its derivatives have been shown to interfere with the quorum sensing (QS) systems of a wide range of bacterial pathogens. While indole has been previously shown to inhibit QS in Serratia marcescens, the effects of various indole derivatives on
Sivasamy Sethupathy +4 more
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RpoS and indole signaling control the virulence of Vibrio anguillarum towards gnotobiotic sea bass (Dicentrarchus labrax) larvae. [PDF]
PLoS ONE, 2014 Quorum sensing, bacterial cell-to-cell communication with small signal molecules, controls the virulence of many pathogens. In contrast to other vibrios, neither the VanI/VanR acylhomoserine lactone quorum sensing system, nor the three-channel quorum ...
Xuan Li +4 more
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mSystems, 2019 Clostridium (Clostridioides) difficile infection (CDI) is associated with dysbiosis. C. difficile has a characteristic propensity to persist and recur 1 to 4 weeks after treatment, but the mechanism is unknown. We hypothesized that C.
Charles Darkoh +3 more
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Indole production capacity in three different Escherichia coli strains [PDF]
Journal of Advanced Pharmacy ResearchBackground: In Escherichia coli, the enzyme tryptophanase (TnaA) is responsible for the production of indole from tryptophan. However, the factors governing the production and excretion levels of indole by Escherichia coliremain uncertain, complicating ...
Galila Salama +3 more
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PLoS ONE, 2015 During the transition from exponential to stationary phase E. coli produces a substantial quantity of the small, aromatic signalling molecule indole. In LB medium the supernatant indole concentration reaches a maximum of 0.5-1 mM.
Hannah Gaimster, David Summers
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Characterization of indole-3-pyruvic acid pathway-mediated biosynthesis of auxin in Neurospora crassa. [PDF]
PLoS ONE, 2018 Plants, bacteria and some fungi are known to produce indole-3-acetic acid (IAA) by employing various pathways. Among these pathways, the indole-3-pyruvic acid (IPA) pathway is the best studied in green plants and plant-associated beneficial microbes ...
Puspendu Sardar, Frank Kempken
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Bacterial Indole as a Multifunctional Regulator of Klebsiella oxytoca Complex Enterotoxicity
mBio, 2022 Gastrointestinal microbes respond to biochemical metabolites that coordinate their behaviors. Here, we demonstrate that bacterial indole functions as a multifactorial mitigator of Klebsiella grimontii and Klebsiella oxytoca pathogenicity.
Nagender Ledala +20 more
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Microbiology Research, 2021 Quorum sensing (QS) is a form of bacterial communication involved in the production of virulence factors in many species. As a result, inhibition of quorum sensing may be of use in mitigating pathogenesis. The signaling molecule indole is currently being
Chesley A. Kemp +3 more
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Targeting the gut microbial metabolic pathway with small molecules decreases uremic toxin production
Gut Microbes, 2020 Uremic toxins are a class of toxins that accumulate in patients with chronic kidney disease (CKD). Indoxyl sulfate (IS), a typical uremic toxin, is not efficiently removed by hemodialysis.
Yingyi Wang +10 more
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