Results 21 to 30 of about 82,415 (199)

Indole ring oxidation by activated leukocytes prevents the production of hypochlorous acid

open access: yesBrazilian Journal of Medical and Biological Research, 2005
Hypochlorous acid (HOCl) released by activated leukocytes has been implicated in the tissue damage that characterizes chronic inflammatory diseases. In this investigation, 14 indole derivatives, including metabolites such as melatonin, tryptophan and ...
V.F. Ximenes   +4 more
doaj   +1 more source

Bacterial Production of Indole Related Compounds Reveals Their Role in Association Between Duckweeds and Endophytes

open access: yesFrontiers in Chemistry, 2018
Duckweed farming can be a sustainable practice for biofuel production, animal feed supplement, and wastewater treatment, although large scale production remains a challenge.
Sarah Gilbert   +5 more
doaj   +1 more source

Selección y caracterización de rizobacterias promotoras de crecimiento vegetal (RPCV) asociadas al cultivo de algodón (Gossypium hirsutum)

open access: yesRevista Colombiana de Biotecnología, 2012
Título en ingles: Selection and characterization of plant growth promoting rhizobacteria (PGPR’s) associated with cotton crop (Gossypium hirsutum) Resumen: Como parte de las estrategias de una agricultura sostenible, se hace necesario disminuir el uso ...
Andrés Guzmán   +3 more
doaj   +2 more sources

In vitro activity of AST-120 that suppresses indole signaling in Escherichia coli, which attenuates drug tolerance and virulence.

open access: yesPLoS ONE, 2020
AST-120 (Kremezin) is used to treat progressive chronic kidney disease (CKD) by adsorbing uremic toxin precursors produced by gut microbiota, such as indole and phenols. In this study, we propose that AST-120 reduces indole level, consequently suppresses
Hidetada Hirakawa   +5 more
doaj   +1 more source

Indole at low concentration helps exponentially growing Escherichia coli survive at high temperature. [PDF]

open access: yesPLoS ONE, 2017
A culture of stationary phase Escherichia coli cells has been reported to produce copious indole when exposed to high temperature (50°C), and this response has been proposed to aid survival.
Junyan Liu, David Summers
doaj   +1 more source

Aniline is an inducer, and not a precursor, for indole derivatives in Rubrivivax benzoatilyticus JA2. [PDF]

open access: yesPLoS ONE, 2014
Rubrivivax benzoatilyticus JA2 and other anoxygenic photosynthetic bacteria produce indole derivatives when exposed to aniline, a xenobiotic compound. Though this phenomenon has been reported previously, the role of aniline in the production of indoles ...
Mohammed Mujahid   +2 more
doaj   +1 more source

Pulmonary immune cell trafficking promotes host defense against alcohol-associated Klebsiella pneumonia

open access: yesCommunications Biology, 2021
Samuelson et al show that alcohol impairs the production/processing of microbial metabolites, specifically tryptophan catabolites, resulting in immune dysregulation and impaired cellular trafficking for optimal host defense.
Derrick R. Samuelson   +6 more
doaj   +1 more source

Optimization of the growth conditions through response surface methodology and metabolomics for maximizing the auxin production by Pantoea agglomerans C1

open access: yesFrontiers in Microbiology, 2023
IntroductionThe fermentative production of auxin/indole 3-acetate (IAA) using selected Pantoea agglomerans strains can be a promising approach to developing novel plant biostimulants for agriculture use.MethodsBy integrating metabolomics and fermentation
Francesca Melini   +6 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

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