Results 51 to 60 of about 6,485 (180)

Revealing the Hypoglycemic Effects and Mechanism of GABA-Rich Germinated Adzuki Beans on T2DM Mice by Untargeted Serum Metabolomics

Frontiers in Nutrition, 2021
Type 2 diabetes mellitus (T2DM) is one of the most common metabolic diseases, and exploring strategies to prevent and treat diabetes has become extremely important.
Xiujie Jiang, Xiujie Jiang, Qingpeng Xu, Aiwu Zhang, Yong Liu, Zhijiang Li, Huacheng Tang, Huacheng Tang, Dongmei Cao, Dongjie Zhang, Dongjie Zhang   +10 more
doaj   +1 more source

Polygonatum cyrtonema Polysaccharides‐Derived Metabolic Meta Alleviates ALD via a Gut–Liver Axis–Mediated, Bifidobacterium pseudolongum–Driven Suppression of the AA Metabolism–MAPK Signaling Network

Food Frontiers, Volume 7, Issue 4, July 2026.
This study demonstrates that the hepatoprotective effect of Polygonatum cyrtonema polysaccharide (PCP) is mediated by its gut microbiota‐derived metabolome, which enriches Bifidobacterium pseudolongum, suppresses the gut–liver axis of AA metabolism, and inhibits hepatic MAPK signaling. ABSTRACT Polygonatum cyrtonema, a traditional Chinese medicinal and
Xingcai Gao, Qing Zhou, Baoting Liu, Jun Li, Jianhua Xie, Yi Chen, Chenxu Gong, Xiaobo Hu, Qiang Yu   +8 more
wiley   +1 more source

PEPC of sugarcane regulated glutathione S-transferase and altered carbon–nitrogen metabolism under different N source concentrations in Oryza sativa

BMC Plant Biology, 2021
Background Phosphoenolpyruvate carboxylase (PEPC) plays an important role in the primary metabolism of higher plants. Several studies have revealed the critical importance of PEPC in the interaction of carbon and nitrogen metabolism.
Ling Lian, Yuelong Lin, Yidong Wei, Wei He, Qiuhua Cai, Wei Huang, Yanmei Zheng, Huibin Xu, Fuxiang Wang, Yongsheng Zhu, Xi Luo, Huaan Xie, Jianfu Zhang   +12 more
doaj   +1 more source

Role of Gram‐Negative Bacterial Infections in Acute‐On‐Chronic Liver Failure

Liver International, Volume 46, Issue 7, July 2026.
ABSTRACT Acute‐on‐chronic liver failure (ACLF) is a systemic disease characterised by an acute clinical deterioration of pre‐existing liver cirrhosis leading to multiple organ failure due to systemic inflammation. It may be triggered by the translocation of bacteria and bacterial compounds across the gut barrier.
Camilla Cadoli, Volker Müller, Christoph Welsch, Heiko Mühl, Jonel Trebicka, Volkhard A. J. Kempf   +5 more
wiley   +1 more source

Transport of Indoleacetic Acid in Intact Corn Coleoptiles [PDF]

Plant Physiology, 1990
We have characterized the transport of [(3)H]indoleacetic acid (IAA) in intact corn (Zea mays L.) coleoptiles. We have used a wide range of concentrations of added IAA (28 femtomoles to 100 picomoles taken up over 60 minutes). The shape of the transport curve varies with the concentration of added IAA, although the rate of movement of the observed ...
K E, Parker, W R, Briggs
openaire   +2 more sources

Plant‐Derived Melatonin Inhibits Bacterial Virulence via CpxA/R Two‐Component System

Advanced Science, Volume 13, Issue 32, 9 June 2026.
Plant‐derived melatonin is sensed by CpxAE48/T51, which inhibits the phosphorylation cascade transmission from CpxAH240 to CpxRD52, resulting in the inhibition of DNA‐binding capacity of CpxR and subsequent T3SS genes expression in Pst DC3000. ABSTRACT In defending against pathogens, plants deploy diverse secondary metabolites and signaling molecules ...
Jin‐Wei Wei, Wei Liu, Bili Cao, Dan Zhao, Chengqiang Wang, Xin Hou, Tangyuan Ning, Biao Gong   +7 more
wiley   +1 more source

Effect of Salinity on Secondary Metabolites and Antioxidant Activity in Callus Extracts of Hyssopus officinalis L.

Техника и технология пищевых производств
Callus cultures of medicinal plants have good prospects for biotechnology as sources of bioactive compounds. Hyssop callus cultures (Hyssopus officinalis L.) possess unique chemical composition and properties.
Popova Elena
doaj   +1 more source

Enhanced production of cordycepin in Ophiocordyceps sinensis using growth supplements under submerged conditions

Biotechnology Reports, 2020
Cordycepin is a crucial bioactive compound produced by the fungus Cordyceps spp. Its therapeutic potential has been recognized for a wide range of biological properties such as anticancer, anti-diabetic, antidepressant, antioxidant, immunomodulation, etc.
Vikas Kaushik, Amanvir Singh, Aditi Arya, Sangeeta Chahal Sindhu, Anil Sindhu, Ajay Singh   +5 more
doaj   +1 more source

Encephalopathy: Cause, Pathogenesis, and Treatment

MedComm, Volume 7, Issue 6, June 2026.
Various encephalopathies (sepsis‐associated, hepatic, hypoxic–ischemic, diabetic, uremic, toxic) have incompletely elucidated pathogenesis, which severely restricts targeted therapy development. Small molecule drugs show unique multitarget potential but face toxicity, poor blood–brain barrier penetration and unclear specificity.
Shimeng Lv, Xia Zhong, Ruirui Shang, Linghui Kong, Yufei Huang, Yuexiang Ma, Jing Teng, Sheng Wei   +7 more
wiley   +1 more source

The Structure of Carboxyl Methyltransferase Provides Insights Into the Substrate Specificity and Divergent Evolution of Iridoid

Plant Biotechnology Journal, Volume 24, Issue 6, Page 3708-3722, June 2026.
ABSTRACT Iridoids constitute a prominent class of plant‐specialised metabolites, with carbocyclic iridoids (e.g., geniposide) and secoiridoids (e.g., loganin) diverging early in their biosynthetic pathways. This divergence is marked by substrate‐specific carboxyl methyltransferases—GjGAMT and CrLAMT—that catalyse the decisive methylation step in ...
Li Li, Zhiteng Luo, Zhaoyin He, Jie Tang, Wuke Wei, Ruoting Zhan, Huihao Zhou, Dongming Ma   +7 more
wiley   +1 more source