Results 111 to 120 of about 200,870 (399)
An entry to indole quinones using in situ generated nitrobenzoquinone [PDF]
, 2018 A direct synthesis of polycyclic indoles from nitrohydroquinone and indoles is reported.
Kraus, George +2 more
core +3 more sources
Continuous Flow Synthesis of α‐Chloroketones from Esters
Advanced Synthesis &Catalysis, EarlyView.Abstract Herein, we report a novel and practical strategy to access α‐chloroketones from esters bearing diverse (hetero)aromatic, aliphatic, alkynyl and alkenyl substituents with transient chloromethyllithium under continuous flow conditions. This highly chemoselective method enables a fast (on a time scale of <5 s), efficient and straightforward ...
Léna Brassart +7 more
wiley +1 more source
(1H-Benzo[d][1,2,3]triazol-1-yl)(5-bromo-1-hydroxy-1H-indol-3-yl)methanone
Molbank, 2014 The title compound was easily prepared by a nitrosoarene-alkyne cycloaddition reaction carried out in toluene at 80 °C. The product is a highly functionalized compound that can be further derivatized through various functional group interconversion ...
Francesco Tibiletti +5 more
doaj +1 more source
Antibiofilm and Antivirulence Properties of Indoles Against Serratia marcescens
Frontiers in Microbiology, 2020 Indole and its derivatives have been shown to interfere with the quorum sensing (QS) systems of a wide range of bacterial pathogens. While indole has been previously shown to inhibit QS in Serratia marcescens, the effects of various indole derivatives on
Sivasamy Sethupathy +4 more
doaj +1 more source
Advanced Synthesis &Catalysis, EarlyView.Abstract The demonstrated light‐initiated addition of radicals formed on an active methylene group to styrene derivatives exhibits a product selectivity influenced by the presence of a protic solvent. Under protic conditions, the predominant products are branched compounds with the alkene moiety attached to the methylene group.
Małgorzata Pałyga +2 more
wiley +1 more source
Bis(4-hydroxy-N-isopropyl-N-methyltryptammonium) fumarate: a new crystalline form of miprocin
Acta Crystallographica Section E: Crystallographic Communications, 2020 The title compound, bis(4-hydroxy-N-isopropyl-N-methyltryptammonium) (4-HO-MiPT) fumarate (systematic name: bis{[2-(4-hydroxy-1H-indol-3-yl)ethyl](methyl)propan-2-ylazanium} but-2-enedioate), 2C14H21N2O+·C4H2O42−, has a singly protonated tryptammonium ...
Andrew R. Chadeayne +3 more
doaj +1 more source
Recent Advances in the Regioselective Synthesis of Indoles via C–H Activation/Functionalization
Synthesis, 2018 Indole is an important heterocyclic motif that occurs ubiquitously in bioactive natural products and pharmaceuticals. Immense efforts have been devoted to the synthesis of indoles starting from the Fisher indole synthesis to the recently developed C–H ...
I. Kumar, Rakesh Kumar, U. Sharma
semanticscholar +1 more source
Catalytic enantioselective synthesis of quaternary carbon stereocentres. [PDF]
, 2014 Quaternary carbon stereocentres-carbon atoms to which four distinct carbon substituents are attached-are common features of molecules found in nature. However, before recent advances in chemical catalysis, there were few methods of constructing single ...
Overman, Larry E, Quasdorf, Kyle W
core
Brønsted Acid Catalyzed Alkylation of Indoles with Tertiary Propargylic Alcohols: Scope and Limitations [PDF]
, 2010 Direct alkylation of indoles with a wide variety of tertiary propargylic alcohols under Brønsted acid catalysis conditions has been studied. A general and environmentally friendly method for the synthesis of 3-propargylated indoles with quaternary carbon
Fernández Rodríguez, Manuel A. +7 more
core +1 more source
Advanced Synthesis &Catalysis, EarlyView.Abstract Pd‐catalyzed reactions are among the most straightforward and efficient methods to proficiently build Csp2‐Csp2 bonds. Nevertheless, thermal activation remains mandatory in most cases, which may decrease the compatibility with sensitive functional groups.
Jenifer Sharshonov +7 more
wiley +1 more source