Results 11 to 20 of about 27,606 (220)

Marine Indole Alkaloids [PDF]

open access: yesMarine Drugs, 2015
Marine indole alkaloids comprise a large and steadily growing group of secondary metabolites. Their diverse biological activities make many compounds of this class attractive starting points for pharmaceutical development. Several marine-derived indoles were found to possess cytotoxic, antineoplastic, antibacterial and antimicrobial activities, in ...
Netz, Natalie, Opatz, Till
openaire   +4 more sources

Natural Indole Alkaloids from Marine Fungi: Chemical Diversity and Biological Activities

open access: yesPharmaceutical Fronts, 2021
The indole scaffold is one of the most important heterocyclic ring systems for pharmaceutical development, and serves as an active moiety in several clinical drugs.
Jiao Li, Chun-Lin Zhuang
doaj   +1 more source

Identification of novel flavin-dependent monooxygenase from Strobilanthes Cusia reveals molecular basis of indoles’ biosynthetic logic

open access: yesBMC Plant Biology, 2023
Background Strobilanthes cusia (Nees) Kuntze is a traditional medical plant distributed widely in south China. The indole compounds that originated from the plant are responsible for its pharmacological activities.
Chang Liu   +4 more
doaj   +1 more source

Oxidative Dearomative Cross-Dehydrogenative Coupling of Indoles with Diverse C-H Nucleophiles: Efficient Approach to 2,2-Disubstituted Indolin-3-ones

open access: yesMolecules, 2020
The oxidative, dearomative cross-dehydrogenative coupling of indoles with various C-H nucleophiles is developed. This process features a broad substrate scope with respect to both indoles and nucleophiles, affording structurally diverse 2,2-disubstituted
Xue Yan   +4 more
doaj   +1 more source

Recent Developments in Ultrasound-Promoted Aqueous-Mediated Greener Synthesis of Biologically Vital Indole Derivatives

open access: yesSynOpen, 2023
The extensive range of uses of N-heterocycles as potent bioactive motifs has attracted researchers to expand newer methods for their efficient synthesis. Particularly, indoles are widely known for their prevalent pharmacological properties.
Kanaram Choupra   +4 more
doaj   +1 more source

Data for the lipase catalyzed synthesis of cyano-containing multi-substituted indoles

open access: yesData in Brief, 2021
The data presented here are related to the research paper entitled “Efficient Synthesis of Cyano-containing Multi-substituted Indoles Catalyzed by Lipase” [1].
Fengxi Li   +5 more
doaj   +1 more source

Fluorescent Pyranoindole Congeners: Synthesis and Photophysical Properties of Pyrano[3,2-f], [2,3-g], [2,3-f], and [2,3-e]Indoles

open access: yesMolecules, 2022
This paper reports the synthesis of four types of annulated pyranoindole congeners: pyrano[3,2-f]indole, pyrano[2,3-g]indole, pyrano[2,3-f]indole, and pyrano[2,3-e]indole and photophysical studies in this series.
Ainur D. Sharapov   +11 more
doaj   +1 more source

Synthesis of indoles, indolines, and carbazoles via palladium-catalyzed C–H activation

open access: yesGreen Synthesis and Catalysis, 2021
The construction of indole, indoline and carbazole heterocycles has been of significant interest in the synthetic community over the last century due to their prevalence in natural products and other biologically active compounds.
Alexander J. Rago, Guangbin Dong
doaj   +1 more source

Regioselectivity of the SEAr-based cyclizations and SEAr-terminated annulations of 3,5-unsubstituted, 4-substituted indoles

open access: yesBeilstein Journal of Organic Chemistry, 2022
Indole-3,4- and 4,5-fused carbo- and heterocycles are ubiquitous in bioactive natural products and pharmaceuticals, and hence, a variety of synthetic approaches toward such compounds have been developed.
Jonali Das, Sajal Kumar Das
doaj   +1 more source

Bufotenidinium iodide

open access: yesIUCrData, 2021
The title compound, 5-hydroxy-N,N,N-trimethyltryptammonium (5-HTQ) iodide {systematic name: [2-(5-hydroxy-1H-indol-3-yl)ethyl]trimethylazanium iodide}, C13H19N2O+·I−, has a single tryptammonium cation and one iodide anion in the asymmetric unit. The ions
Duyen N. K. Pham   +3 more
doaj   +1 more source

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