Results 11 to 20 of about 104,731 (310)
Communications Chemistry, 2021 Dearomatisation of indoles allows efficient access to indolines, but often is incompatible with electron-withdrawing substituents. Here a photoredox Giese-type dearomatisation of indoles yields 2,3-disubstituted indolines bearing electron-withdrawing ...
Yueteng Zhang +7 more
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Recent Progress Concerning the N-Arylation of Indoles
Molecules, 2021 This review summarizes the current state-of-the-art procedures in terms of the preparation of N-arylindoles. After a short introduction, the transition-metal-free procedures available for the N-arylation of indoles are briefly discussed. Then, the nickel-
Petr Oeser +3 more
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Natural Indole Alkaloids from Marine Fungi: Chemical Diversity and Biological Activities
Pharmaceutical Fronts, 2021 The indole scaffold is one of the most important heterocyclic ring systems for pharmaceutical development, and serves as an active moiety in several clinical drugs.
Jiao Li, Chun-Lin Zhuang
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BMC Plant Biology, 2023 Background Strobilanthes cusia (Nees) Kuntze is a traditional medical plant distributed widely in south China. The indole compounds that originated from the plant are responsible for its pharmacological activities.
Chang Liu +4 more
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Molecules, 2020 The oxidative, dearomative cross-dehydrogenative coupling of indoles with various C-H nucleophiles is developed. This process features a broad substrate scope with respect to both indoles and nucleophiles, affording structurally diverse 2,2-disubstituted
Xue Yan +4 more
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Focus on chirality of HIV-1 non-nucleoside reverse transcriptase inhibitors [PDF]
, 2016 Chiral HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) are of great interest since one enantiomer is often more potent than the corresponding counterpart against the HIV-1 wild type (WT) and the HIV-1 drug resistant mutant strains.
Famiglini, Valeria, Silvestri, Romano
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SynOpen, 2023 The extensive range of uses of N-heterocycles as potent bioactive motifs has attracted researchers to expand newer methods for their efficient synthesis. Particularly, indoles are widely known for their prevalent pharmacological properties.
Kanaram Choupra +4 more
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Molecules, 2022 This paper reports the synthesis of four types of annulated pyranoindole congeners: pyrano[3,2-f]indole, pyrano[2,3-g]indole, pyrano[2,3-f]indole, and pyrano[2,3-e]indole and photophysical studies in this series.
Ainur D. Sharapov +11 more
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Synthesis of indoles via alkylidenation of acyl hydrazides [PDF]
, 2009 Indoles have been synthesised via alkylidenation of acyl phenylhydrazides using phosphoranes and the Petasis reagent, followed by in situ thermal rearrangement of the product enehydrazines.
Commeureuc, A.G.J. +5 more
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Synthesis of indoles, indolines, and carbazoles via palladium-catalyzed C–H activation
Green Synthesis and Catalysis, 2021 The construction of indole, indoline and carbazole heterocycles has been of significant interest in the synthetic community over the last century due to their prevalence in natural products and other biologically active compounds.
Alexander J. Rago, Guangbin Dong
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