Results 21 to 30 of about 172,313 (331)

Degradation of substituted indoles by an indole-degrading methanogenic consortium [PDF]

open access: yesApplied and Environmental Microbiology, 1991
Degradation of indole by an indole-degrading methanogenic consortium enriched from sewage sludge proceeded through a two-step hydroxylation pathway yielding oxindole and isatin. The ability of this consortium to hydroxylate and subsequently degrade substituted indoles was investigated.
Berry, DF, Gu, JD
openaire   +4 more sources

Synthesis of chiral N-alkylated indoles through replacement of aniline nitrogen by natural amino acids

open access: yesGreen Synthesis and Catalysis, 2022
Chiral N-alkylated indoles are privileged structural motifs found in many natural products and pharmaceuticals and a search for effective methods with which to prepare chiral N-alkylated indoles is ongoing.
Xiaohua Li   +4 more
doaj  

Regioselectivity of the SEAr-based cyclizations and SEAr-terminated annulations of 3,5-unsubstituted, 4-substituted indoles

open access: yesBeilstein Journal of Organic Chemistry, 2022
Indole-3,4- and 4,5-fused carbo- and heterocycles are ubiquitous in bioactive natural products and pharmaceuticals, and hence, a variety of synthetic approaches toward such compounds have been developed.
Jonali Das, Sajal Kumar Das
doaj   +1 more source

Recent Advances of Marine Natural Indole Products in Chemical and Biological Aspects

open access: yesMolecules, 2023
The ocean has always been one of the important sources of natural products. In recent years, many natural products with different structures and biological activities have been obtained, and their value has been clearly recognized.
Haoyi Sun, Kangping Sun, Jingyong Sun
doaj   +1 more source

Green oxidation of indoles using halide catalysis

open access: yesNature Communications, 2019
Oxidation of indoles is a fundamental organic transformation to deliver a variety of synthetically and pharmaceutically valuable nitrogen-containing compounds.
Jun Xu   +4 more
semanticscholar   +1 more source

Chemoselective N-acylation of indoles using thioesters as acyl source

open access: yesBeilstein Journal of Organic Chemistry, 2022
The selective acylation of indoles often requires sensitive and reactive acyl chloride derivatives. Here, we report a mild, efficient, functional group tolerant, and highly chemoselective N-acylation of indoles using thioesters as a stable acyl source. A
Tianri Du   +7 more
doaj   +1 more source

The methanol and ethanol solvates of 4-glutarato-N,N-diisopropyltryptamine

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2022
The solid-state structures of two solvated forms of 4-glutarato-N,N-diisopropyltryptamine were determined by single-crystal X-ray diffraction, namely, 5-[(3-{2-[bis(propan-2-yl)azaniumyl]ethyl}-1H-indol-4-yl)oxy]-5-oxopentanoate methanol monosolvate ...
Marilyn Naeem   +4 more
doaj   +1 more source

A General and Scalable Synthesis of Polysubstituted Indoles

open access: yesMolecules, 2020
A consecutive 2-step synthesis of N-unprotected polysubstituted indoles bearing an electron-withdrawing group at the C-3 position from readily available nitroarenes is reported.
David Tejedor   +2 more
doaj   +1 more source

Antibiofilm and Antimicrobial Activities of Chloroindoles Against Uropathogenic Escherichia coli

open access: yesFrontiers in Microbiology, 2022
Uropathogenic Escherichia coli (UPEC) is a nosocomial pathogen associated with urinary tract infections and expresses several virulence factors that cause recurring infections and cystitis of the bladder, which can lead to pyelonephritis.
Bharath Reddy Boya   +2 more
doaj   +1 more source

Electrochemical Dearomative 2,3-Difunctionalization of Indoles.

open access: yesJournal of the American Chemical Society, 2018
We report the use of electrochemistry to perform a direct oxidative dearomatization of indoles leading to 2,3-dialkoxy or 2,3-diazido indolines under undivided conditions at a constant current. This operationally simple electro-oxidative procedure avoids
Juinn-Yao Wu   +4 more
semanticscholar   +1 more source

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