High throughput synthesis of 2,5-substituted indoles using a titanium carbenoid bearing boronate functionality [PDF]
, 2008 A titanium benzylidene complex bearing a boronate group converted resin-bound esters into enol ethers. Suzuki cross-coupling with aryl iodides followed by cleavage with acid completed the solid-phase synthesis of 2,5-disubstituted N-Boc-indoles.
Hartley, R.C. +3 more
core +1 more source
Data for the lipase catalyzed synthesis of cyano-containing multi-substituted indoles
Data in Brief, 2021 The data presented here are related to the research paper entitled “Efficient Synthesis of Cyano-containing Multi-substituted Indoles Catalyzed by Lipase” [1].
Fengxi Li +5 more
doaj +1 more source
Synthetic Analogues of the Snail Toxin 6-Bromo-2-mercaptotryptamine Dimer (BrMT) Reveal That Lipid Bilayer Perturbation Does Not Underlie Its Modulation of Voltage-Gated Potassium Channels [PDF]
, 2018 Drugs do not act solely by canonical ligand–receptor binding interactions. Amphiphilic drugs partition into membranes, thereby perturbing bulk lipid bilayer properties and possibly altering the function of membrane proteins.
Aldrich, Richard W. +12 more
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Regioselective Formation of α-Vinylpyrroles from the Ruthenium-Catalyzed Coupling Reaction of Pyrroles and Terminal Alkynes Involving C–H Bond Activation [PDF]
, 2010 The cationic ruthenium catalyst Ru3(CO)12/NH4PF6 was found to be highly effective for the intermolecular coupling reaction of pyrroles and terminal alkynes to give gem-selective α-vinylpyrroles.
Gao, Ruili, Yi, Chae S.
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Regioselective Reaction of 2-Indolylmethanols with Enamides
Molecules, 2023 A highly regioselective reaction of 2-indolylmethanols with enamides has been developed at room temperature by using AlCl3 as a catalyst. A wide range of hybrids (40 examples) of indoles and enamides were obtained in moderate to good yields (up to 98 ...
Yuting Tian +7 more
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Polar Diels-Alder Reactions using Heterocycles as Electrophiles. Influence of Microwave Irradiation [PDF]
, 2015 In this work we studied a series of polar Diels-Alder reactions using different heterocycles derivatives acting as electrophiles joint to dienes of different nucleophilicity, analyzing the effect of the microwave irradiation in these processes. We employ
Della Rosa, Claudia Daniela +3 more
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Recent Advances of Marine Natural Indole Products in Chemical and Biological Aspects
Molecules, 2023 The ocean has always been one of the important sources of natural products. In recent years, many natural products with different structures and biological activities have been obtained, and their value has been clearly recognized.
Haoyi Sun, Kangping Sun, Jingyong Sun
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Development of indole sulfonamides as cannabinoid receptor negative allosteric modulators [PDF]
, 2016 This Letter was supported by the Biotechnology and Biological Sciences Research Council (BBSRC) and the Scottish Universities Life Sciences Alliance (SULSA) in 2011Peer ...
Abdelrahman, Mostafa Hamed +4 more
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Beilstein Journal of Organic Chemistry, 2022 Indole-3,4- and 4,5-fused carbo- and heterocycles are ubiquitous in bioactive natural products and pharmaceuticals, and hence, a variety of synthetic approaches toward such compounds have been developed.
Jonali Das, Sajal Kumar Das
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IUCrData, 2021 The title compound, 5-hydroxy-N,N,N-trimethyltryptammonium (5-HTQ) iodide {systematic name: [2-(5-hydroxy-1H-indol-3-yl)ethyl]trimethylazanium iodide}, C13H19N2O+·I−, has a single tryptammonium cation and one iodide anion in the asymmetric unit. The ions
Duyen N. K. Pham +3 more
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