Results 21 to 30 of about 200,870 (399)
SynOpen, 2023 The extensive range of uses of N-heterocycles as potent bioactive motifs has attracted researchers to expand newer methods for their efficient synthesis. Particularly, indoles are widely known for their prevalent pharmacological properties.
Kanaram Choupra +4 more
doaj +1 more source
Synthesis of indoles via alkylidenation of acyl hydrazides [PDF]
, 2009 Indoles have been synthesised via alkylidenation of acyl phenylhydrazides using phosphoranes and the Petasis reagent, followed by in situ thermal rearrangement of the product enehydrazines.
Commeureuc, A.G.J. +5 more
core +1 more source
New Approaches to Indoles and Indole Alkaloids [PDF]
Proceedings of the 14th Brazilian Meeting on Organic Synthesis Proceedings, 2013 Second only to pyridines, indoles are among the most common aromatic scaffolds present in bioactive molecules. The 5-hydroxy indole moiety alone has currently >10,500 substructure hits Among the many indole-containing alkaloid scaffolds, ergot alkaloids comprise a notable group of natural products of great biological activities. The striking biological
Filip Petronijevic, Peter Wipf
openaire +2 more sources
Resistive switching of tetraindolyl derivative in ultrathin films: A potential candidate for non-volatile memory applications [PDF]
Langmuir (2021), 2021 Bipolar resistive switching using organic molecule is very promising for memory application owing to their advantages like simple device structure, low manufacturing cost, their stability and flexibility etc. Herein we report Langmuir-Blodgett and spin-coated film based bipolar resistive switching devices using organic material indole derivative ...
arxiv +1 more source
High throughput synthesis of 2,5-substituted indoles using a titanium carbenoid bearing boronate functionality [PDF]
, 2008 A titanium benzylidene complex bearing a boronate group converted resin-bound esters into enol ethers. Suzuki cross-coupling with aryl iodides followed by cleavage with acid completed the solid-phase synthesis of 2,5-disubstituted N-Boc-indoles.
Hartley, R.C. +3 more
core +1 more source
Natural Product Reports, 2013 The natural product sesquiterpenyl indoles are structural hybrids from farnesyl pyrophosphate and tryptophan or its precursors, often with unusual and complex structural features, many of them with interesting biological activities. In this review the compounds of this class known until now are classified, a biosynthetic approach of each group is ...
Marcos, Isidro S. +4 more
openaire +3 more sources
Polar Diels-Alder Reactions using Heterocycles as Electrophiles. Influence of Microwave Irradiation [PDF]
, 2015 In this work we studied a series of polar Diels-Alder reactions using different heterocycles derivatives acting as electrophiles joint to dienes of different nucleophilicity, analyzing the effect of the microwave irradiation in these processes. We employ
Della Rosa, Claudia Daniela +3 more
core +1 more source
Synthesis of 5,7-diarylindoles via Suzuki-Miyaura coupling in water [PDF]
, 2021 The synthesis of novel 5,7-diaryl and diheteroaryl indoles has been explored via efficient double Suzuki–Miyaura coupling. The method notably employs a low catalyst loading of Pd(PPh3)4 (1.5 mol%/coupling) and water as the reaction solvent to obtain 5,7 ...
Elumalai, Vijayaragavan, Hansen, Jørn H
core +1 more source
Molecules, 2022 This paper reports the synthesis of four types of annulated pyranoindole congeners: pyrano[3,2-f]indole, pyrano[2,3-g]indole, pyrano[2,3-f]indole, and pyrano[2,3-e]indole and photophysical studies in this series.
Ainur D. Sharapov +11 more
doaj +1 more source
Heterocyclic scaffolds as promising anticancer agents against tumours of the central nervous system: Exploring the scope of indole and carbazole derivatives [PDF]
, 2014 Tumours of the central nervous system are intrinsically more dangerous than tumours at other sites, and in particular, brain tumours are responsible for 3% of cancer deaths in the UK. Despite this, research into new therapies only receives 1% of national
Akinaga +117 more
core +1 more source