Indolinyl-Thiazole Based Inhibitors of Scavenger Receptor-BI (SR-BI)-Mediated Lipid Transport [PDF]
A potent class of indolinyl-thiazole based inhibitors of cellular lipid uptake mediated by scavenger receptor, class B, type I (SR-BI) was identified via a high-throughput screen of the National Institutes of Health Molecular Libraries Small Molecule ...
Bennion, Melissa +18 more
core +3 more sources
Spiropyran modified micro-fluidic chip channels as photonically controlled self-indicating system for metal ion accumulation and release [PDF]
In this paper, we show how through integrating the beneficial characteristics of micro-fluidic devices and spiropyrans dyes, a simple and very innovative chip configured as an on-line photonically controlled self-indicating system for metal ion ...
Attia +51 more
core +1 more source
1-(Morpholinomethyl)indoline-2,3-dione [PDF]
In the title compound, C(13)H(14)N(2)O(3), the morpholine ring displays a chair conformation, with the (2,3-dioxoindolin-1-yl)methyl group in an equatorial position. The crystal structure is stabilized by inter-molecular C-H⋯O hydrogen bonds.
Tang, Y, Zhang, J, Miao, Y, Chen, G
openaire +3 more sources
5′,6-Dichloro-1′,3′,3′-trimethylspiro[2H-1-benzopyran-2,2′-indoline]
In the crystal structure of the title compound, C19H17Cl2NO, the indoline and benzopyran ring systems are approximately perpendicular to each other. The indoline ring is in an envelope conformation with the spiro C atom as the flap.
Nameer Alhashimy +3 more
doaj +1 more source
Efficient Dehydrogenation of Amines and Carbonyl Compounds Catalyzed by a Tetranuclear Ruthenium-μ-oxo-μ-hydroxo-hydride Complex [PDF]
The tetranuclear ruthenium-μ-oxo-μ-hydroxo-hydride complex {[(PCy3)(CO)RuH]4(μ4-O)(μ3-OH)(μ2-OH)} (1) was found to be a highly effective catalyst for the transfer dehydrogenation of amines and carbonyl compounds. For example, the initial turnover rate of
Lee, Do W., Yi, Chae S.
core +2 more sources
Synthesis of a Spirocyclic Indoline Lactone [PDF]
AbstractFor Abstract see ChemInform Abstract in Full Text.
John C, Hodges, Wei, Wang, Frank, Riley
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Methyl 5′-Chloro-8-formyl-5-hydroxy-1′,3′,3′-trimethyl-spiro-[chromene-2,2′-indoline]-6-carboxylate
Spiropyrans modified with reactive polyfunctional substituents are of great interest as building blocks for the creation of various smart systems with controllable properties for materials science and biomedicine.
Ilya V. Ozhogin +8 more
doaj +1 more source
Investigation of Structural Dynamics of Enzymes and Protonation States of Substrates Using Computational Tools. [PDF]
This review discusses the use of molecular modeling tools, together with existing experimental findings, to provide a complete atomic-level description of enzyme dynamics and function.
Chang, Chia-En A +3 more
core +2 more sources
In the presence of triethylamine as catalyst, the one-pot four-component reactions of arylamines, methyl propiolate, isatin and malononitrile afforded the functionalized spiro[indoline-3,4’-pyridine] derivatives in good yields.
Li-Juan Zhang +3 more
doaj +1 more source
Methyl 2-(5-chloro-1-methyl-2-oxo-2,3-dihydro-1H-indol-3-ylidene)acetate
The title compound, C12H10ClNO3, the indoline ring system is essentially planar, with a maximum deviation of 0.009 Å for the N atom. The indoline ring and acetate group are essentially coplanar, with a maximum deviation of 0.086 Å ...
Piskala Subburaman Kannan +4 more
doaj +1 more source

