Results 111 to 120 of about 1,816,039 (262)
Chaos for induced hyperspace maps
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +3 more sources
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Crosstalk and spatiotemporal regulation between stress-induced MAP kinase pathways and pheromone signaling in budding yeast. [PDF]
Van Drogen F +6 more
europepmc +1 more source
Induced and inducible mappings between hyperspaces
In this paper we consider H(X) be a hyperspace of a continuum X. Let f : X → Y be a continuous function between continua, consider the induced function H(f) : H(X) → H(Y ) given by H(f)(A) = f(A), for all A ϵ H(X). On the other hand, if we have the continuous function H : H(X) → H(Y ) and there exists g : X → Y such that H = H(f), we say that H is ...
openaire +1 more source
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Some relationships between induced mappings
For a continuum \(X\) and for a positive integer \(n\) let \(2^X\) denote the hyperspace of nonempty closed subsets; let \(C_{n}(X)\) denote the hyperspace of all nonempty closed subsets of \(X\) with at most \(n\) components, and \({\mathcal F}_{n}(X)\) the hyperspace of nonempty finite sets with at most \(n\) points. The \textit{\(n\)-fold hyperspace
openaire +1 more source
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source

