Spatiotemporal Adaptations‐Driven Dynamic Thra Activation Simulates a Skin Wound Healing Response
This study uncovers the thyroid hormone receptor Thra as a pivotal regulator that spatiotemporally orchestrates dual‐phase skin repair. Epidermal Thra accelerates barrier restoration via glutathione‐driven keratin assembly, while dermal Thra establishes angiogenic niches through SAA3‐FN1‐mediated matrix remodeling.
Zeming Li+15 more
wiley +1 more source
Efficient Generation of Induced Pluripotent Stem Cell-Derived Definitive Endoderm Cells with Growth Factors and Small Molecules. [PDF]
Asumda FZ+11 more
europepmc +1 more source
Butyrate Greatly Enhances Derivation of Human Induced Pluripotent Stem Cells by Promoting Epigenetic Remodeling and the Expression of Pluripotency-Associated Genes [PDF]
Prashant Mali+15 more
openalex +1 more source
Naturally derived biomembrane nanostructures by mimicking evolutionarily optimized biological architectures could effectively suppress tumor growth and have emerged as a compelling strategy in translational biomedicine. This review provides a systematic overview of rational design and underlying antitumor therapeutic mechanisms of mammalian cells ...
Xiaodan Wei+10 more
wiley +1 more source
Advances in human induced pluripotent stem cell (hiPSC)-based disease modelling in cardiogenetics. [PDF]
Hoffmann S, Seeger T.
europepmc +1 more source
This manuscript presents a novel framework for evaluating cell viability in the emerging field of magnetothermal stimulation, applied to 2D and 3D cell cultures. It introduces a tunable, stimuli‐responsive magnetic collagen gel designed to support controlled thermal stimulation.
Shahar Shalom+6 more
wiley +1 more source
Generation of canine induced pluripotent stem cell-derived mesenchymal stem cells: Comparison of differentiation strategies and cell origins. [PDF]
Tsukamoto M+7 more
europepmc +1 more source
Induced pluripotent stem cells: what lies beyond the paradigm shift [PDF]
Jesse L. Cox, Angie Rizzino
openalex +1 more source
The potential of human induced pluripotent stem cells for modelling diabetic wound healing in vitro [PDF]
Aasen+150 more
core +1 more source
m6A Modulates RAN Translation From CAG Repeat Expansion RNA
We described a novel role of N6‐methyladenosine in promoting non‐canonical repeat‐associated non‐AUG translation from CAG repeat expansion RNA. ABSTRACT Nucleotide repeat expansions contribute to the development of a number of neurodegenerative diseases.
Yuxiang Sun+3 more
wiley +1 more source