Human induced pluripotent stem cell-derived neural stem/progenitor cell therapy for spinal cord injury: preclinical advances and translational perspectives. [PDF]
Ogaki R, Nagoshi N, Okano H, Nakamura M.
europepmc +1 more source
Back Again to the Future: A New Era for Cerebroprotection
Cerebroprotection is a fresh framework for designing neurological therapy that targets glia and vascular cells, in addition to neurons. In the future, successful cerebroprotection will involve targeting all elements of the neurovascular unit. Preclinical trials must include functional outcomes, as well as lesion morphometry.
Patrick Lyden
wiley +1 more source
Tissue-resident macrophages co-develop with myocardial tissue in human induced pluripotent stem cell-derived organoids. [PDF]
Rockel AF +5 more
europepmc +1 more source
Bioprinted Excitable Tissues with Multistimulation Systems for Promoting Function and Maturation
This review provides an overview of stimulation strategies used to enhance the functional maturation of bioprinted excitable tissues. It addresses key limitations in physiological performance of bioprinted excitable tissues, outlines major stimulation modalities—including electrical, mechanical, optical, magnetic, ultrasound, and hybrid—and examines ...
Uijung Yong, Jinseon Park, Jinah Jang
wiley +1 more source
MicroRNA profiles of four induced pluripotent stem cell lines derived from distinct tissues. [PDF]
Trakarnsanga K +6 more
europepmc +1 more source
3D Hydrogel Cell Cultures and Their Biomedical Applications
The review highlights the advantages of hydrogel‐based 3D cell cultures over traditional 2D models. These hydrogels closely mimic natural cellular environments, improving research in tissue engineering, drug discovery, cancer studies, and neuroscience.
Tri Lan Thai +7 more
wiley +1 more source
Generation of two induced pluripotent stem cell lines from dilated cardiomyopathy patients harbouring TTN mutations. [PDF]
Tan R +6 more
europepmc +1 more source
This review explains how biomaterials and nanoparticles can be used to induce or modulate tertiary lymphoid structures (TLSs), which are ectopic immune hubs that form in nonlymphoid tissues during chronic disease and cancer. By comparing different methods, the article highlights design principles for modeling TLSs or recapitulating specific TLS ...
Shaza Karaman, Mei ElGindi, Jeremy Teo
wiley +1 more source
Mitochondrial dynamics and bioenergetics in Alzheimer's induced pluripotent stem cell-derived neurons. [PDF]
MacMullen C, Sharma N, Davis RL.
europepmc +1 more source

