Results 91 to 100 of about 398,685 (377)
FEBS Open Bio, EarlyView.Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel +3 more
wiley +1 more source
Frontiers in Bioengineering and Biotechnology, 2021 Failure of corneal endothelium cell monolayer is the main cause leading to corneal transplantation. Autologous cell-based therapies are required to reconstruct in vitro the cell monolayer.
Begoña M. Bosch +5 more
doaj +1 more source
Mesenchymal stem cells and induced pluripotent stem cells as therapies for multiple sclerosis. [PDF]
, 2015 Multiple sclerosis (MS) is a chronic, autoimmune, inflammatory demyelinating disorder of the central nervous system that leads to permanent neurological deficits.
Biswas, Sangita +5 more
core +3 more sources
PeerJ, 2018 The discovery of induced pluripotent stem cells (iPSCs) by Shinya Yamanaka in 2006 was heralded as a major breakthrough of the decade in stem cell research.
Adekunle Omole, A. Fakoya
semanticscholar +1 more source
Induced Pluripotent Stem Cells and Periodontal Regeneration [PDF]
Current Oral Health Reports, 2015 Periodontitis is a chronic inflammatory disease which leads to destruction of both the soft and hard tissues of the periodontium. Tissue engineering is a therapeutic approach in regenerative medicine that aims to induce new functional tissue regeneration via the synergistic combination of cells, biomaterials, and/or growth factors.
Xuejing Duan, Mi Du, Pishan Yang
openaire +3 more sources
Advanced Biology, EarlyView.The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran +5 more
wiley +1 more source
Advanced Functional Materials, EarlyView.In this work, melt electrowriting is used to fabricate a 3D printed scaffold design that generates engineered cardiac tissues with in‐plane contraction, mimicking natural myocardium. It is shown that these tissues display advanced maturation and functionality.
Olalla Iglesias‐García +23 more
wiley +1 more source
Induced pluripotent stem cells: advances to applications
Stem Cells and Cloning: Advances and Applications, 2009 Timothy J Nelson1, Almudena Martinez-Fernandez1, Satsuki Yamada1, Yasuhiro Ikeda2, Carmen Perez-Terzic1, Andre Terzic11Marriott Heart Disease Research Program, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, USA; 2Department of ...
Timothy J Nelson +3 more
doaj
Defining differentially methylated regions specific for the acquisition of pluripotency and maintenance in human pluripotent stem cells via microarray. [PDF]
PLoS ONE, 2014 Epigenetic regulation is critical for the maintenance of human pluripotent stem cells. It has been shown that pluripotent stem cells, such as embryonic stem cells and induced pluripotent stem cells, appear to have a hypermethylated status compared with ...
WenYin He +9 more
doaj +1 more source
Our Bodies, Our Cells: FDA Regulation of Autologous Adult Stem Cell Therapies [PDF]
, 2013 Stem cells have been an endless source of fascination and controversy since Dolly the sheep was cloned in 1996. This month’s announcement of a cloned human embryo from a single skin cell came on the heels of Sir John B. Gurdon and Dr.
Chirba, Mary Ann, Noble, Alice
core